Rhinorus, 0.1%, nasal drops, with eucalyptus oil, 10 ml, 1 pc.

Rhinorus, 0.1%, nasal drops, with eucalyptus oil, 10 ml, 1 pc.

Grippostad® S

Inside,

with a small amount of liquid, 2 caps. appointment. If necessary, repeat the same dose after 4-6 hours 3-4 times a day. The maximum daily dose should not exceed 12 caps.

Grippostad® Rhino

Intranasally.

Nasal spray:

adults and children over 6 years old - 1 spray from a spray bottle or 2-3 drops in each nasal passage, 3-4 times a day; should not be used more than 4 times a day.

Nasal drops:

adults and children over 6 years old - 2-3 drops of a 0.1% solution in each nasal passage 3-4 times a day, should not be used more than 4 times a day.

Nasal drops for children:

infants and children under 6 years of age - 1-2 drops of a 0.05% solution in each nasal passage 1 or 2 times a day; should not be used more than 3 times a day.

Grippostad® Rhino (all dosage forms) should not be used for longer than 5–7 days, except as prescribed by a doctor. Repeated use of the drug is possible after a few days. The duration of therapy is determined by the doctor.

Grippostad®

Inside.

The dose of paracetamol depends on age and body weight, in general 10–15 mg/kg body weight once, the maximum daily dose is 60 mg/kg body weight. A single dose (1 pack) is equivalent to 600 mg of paracetamol.

Taking the drug can be repeated after 6–8 hours, i.e. 3–4 packs per day. The interval between taking each dose should be at least 6 hours. Do not exceed a single dose of the drug.

If the patient is simultaneously taking other paracetamol-containing drugs, the maximum permissible daily dose of paracetamol should not be exceeded (see table).

Patients with liver or kidney disease and Gilbert's syndrome:

the dosage should be reduced or the interval between doses increased.

Patients with severe renal impairment:

in such cases (Cl creatinine <10 ml/min), the interval between doses should be at least 8 hours.

Elderly patients:

no special dose adjustment is required.

Method of preparing the solution

Contents 1 pack. You should pour it into a glass, add the required amount of hot water, stir and immediately drink the resulting warm drink.

Use after meals may delay the onset of action of the drug.

Duration of use

The drug should not be used for more than 3 days without a doctor's recommendation. You should consult a doctor if symptoms persist for more than 3 days.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The active ingredient of the drug is a stimulator of α1 and 2-adrenergic receptors of the vessels of the nasopharyngeal mucosa. As a result of its action, the vessels narrow, inflammation and swelling of the mucous membrane decreases. Nasal discharge is significantly reduced and nasal breathing becomes easier.

The additional introduction of eucalyptus oil has an anti-inflammatory and antibacterial effect. This helps reduce swelling of the mucous membrane.

The drug is indicated for rhinitis of various etiologies and diseases of the paranasal sinuses. Its effect lasts about 10 hours.

Pharmacokinetics

Rhinorus does not have a systemic effect when applied topically, since the concentration in the blood plasma is very low.

Rhinorus nasal drops 0.05% drops bottle 10ml

ATX code

R01AA07 (Xylometazoline)
Active ingredient
xylometazoline hydrochloride (xylometazoline)
Release form, composition and packaging
◊ Nasal drops 0.05%

in the form of a transparent, colorless or slightly yellowish liquid with the smell of eucalyptus.

Excipients:

benzalkonium chloride - 0.1 mg, sodium chloride - 5 mg, disodium edetate - 0.5 mg, sodium dihydrogen phosphate dihydrate - 6 mg, sodium hydrogen phosphate dodecahydrate - 3.5 mg, eucalyptus oil - 0.85 mg, liquid water - up to 1 ml.

5 ml - polymer dropper bottle (1) - cardboard packs. 10 ml

— polymer dropper bottle (1) — cardboard packs.
Clinical-pharmacological group
for local use
Pharmaco-therapeutic group
Vasoconstrictor drug for local use in ENT practice
Indications
- acute rhinitis (including against the background of acute respiratory diseases and allergic rhinitis);

- sinusitis;

- eustachitis;

- otitis media (as part of combination therapy to reduce swelling of the nasopharyngeal mucosa);

— to facilitate rhinoscopy;

— preparing patients for diagnostic manipulations in the nasal passages.
Dosage regimen
Nasal drops

Adults and children over 6 years old

instill nasal drops 0.1%, 2-3 drops into each nasal passage 3-4 times a day.

Children from 2 to 6 years old

instill nasal drops 0.05%, 1-2 drops into each nasal passage 1-2 times a day. Should not be used more than 3 times/day.

The duration of treatment is no more than 3-5 days (without a break).

Before using the drug, unscrew the cap of the bottle and instill it into the nose by lightly pressing the bottom of the bottle.

Nasal spray

Adults and children over 6 years old

– 1 injection of 0.1% nasal spray into each nasal passage 3 times a day. If necessary, you can repeat the injection (no more than two injections at a time).

Children from 2 to 6 years old

– 1 injection of nasal spray 0.05% into each nasal passage 1-2 times a day.

The drug should not be used more than 3 times a day. The duration of treatment is no more than 5-7 days (without a break).

After completion of therapy, the drug can be re-administered only after a few days.

The duration of use of the drug in children is determined by the doctor.

Rules for using the drug in the form of a nasal spray

Remove the protective cap from the bottle.
Before the first use, press the spray nozzle several times until a stream with a “cloud of fog” appears. The bottle is ready for use. When injecting, press the spray nozzle once. Inhale the drug through the nose. If possible, keep the spray bottle upright. Do not spray horizontally or downward. After use, close the spray bottle with a protective cap. Side effects
Local reactions:

with frequent and/or prolonged use - irritation and/or dryness of the nasopharyngeal mucosa, burning, paresthesia, sneezing, hypersecretion; rarely - swelling of the nasal mucosa.

Systemic reactions:

vomiting, headache, palpitations, increased blood pressure, insomnia, blurred vision, depression (with long-term use of high doses).
Contraindications for use
: arterial hypertension;

- tachycardia;

- severe atherosclerosis;

- glaucoma;

- atrophic rhinitis;

- hyperthyroidism;

— surgical interventions on the meninges (history);

— pregnancy (for nasal drops);

- children under 2 years of age;

- children under 6 years of age (for nasal drops 0.1% and nasal spray 0.1%);

- hypersensitivity to the components of the drug (including eucalyptus oil).

Do not use during therapy with MAO inhibitors and tricyclic antidepressants, as well as with other drugs that increase blood pressure.

Carefully _

The drug should be prescribed for diabetes mellitus, coronary artery disease, angina pectoris of functional class III-IV, prostatic hyperplasia, and during lactation.
Special instructions
Should not be used for more than 7 days. Do not exceed recommended doses or use for a long time.

Before use, it is necessary to clean the nasal passages.

Impact on the ability to drive vehicles and operate machinery

In doses exceeding the recommended ones, it can affect the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions, which requires caution.
Overdose
Symptoms:

decreased body temperature, bradycardia, increased blood pressure.

Treatment:

carry out symptomatic therapy.
Drug interactions
It is possible to enhance the systemic effect of xylometazoline with the simultaneous use of MAO inhibitors and tricyclic antidepressants.
Conditions for dispensing from pharmacies
The drug is approved for use as an over-the-counter product.
Conditions and periods of storage
The drug should be stored in a dry place, protected from light, out of reach of children, at a temperature not exceeding 25°C.
The shelf life of nasal drops is 3 years, nasal spray is 2 years. Diseases
Suppurative and unspecified otitis media, Inflammation and obstruction of the auditory [eustachian] tube, Acute nasopharyngitis, Acute sinusitis, Allergic rhinitis caused by pollen, Other allergic rhinitis (perennial allergic rhinitis), Chronic sinusitis, Preparatory procedures for subsequent treatment or examination, not classified elsewhere

Reviews about Rinorus

Xylometazoline, the active ingredient in Rhinorus drops, has a longer lasting effect (8-10 hours) than drugs from the phenylephrine .

Positive reviews about Rhinorus boil down to the fact that the long-lasting vasoconstrictor effect allows the drops to be used only 2 times a day. For some patients, this frequency of use is sufficient. Use at night ensures the restoration of patency of the nasal passages during the night and a restful sleep. Users note that the effect of the drug does not appear immediately, but after 10 minutes.

The risk of mucosal atrophy is reduced due to the presence of eucalyptus oil , which, in addition, additionally has a healing effect. Drops, when instilled, enter the throat, and this causes discomfort for many. In addition, the drops are difficult to dose, so side effects may occur. It is safer, and for many more convenient, to use a dosed spray.

Some users report adverse reactions: burning in the nose, increased blood pressure, anxiety, insomnia . To avoid adverse events, it is recommended to strictly adhere to the dosage regimen of the drug.

Rinorus price, where to buy

The drug can be purchased in all pharmacies in Moscow and other Russian cities. The price of Rinorus in the form of 0.1% drops is 19-22 rubles, the cost of 0.1% spray ranges from 65-79 rubles.

• Online pharmacies in RussiaRussia

ZdravCity

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• Rinorus nasal spray. 0.05% 20mlSintez OJSC

  88 rub. order

Analogs

Level 4 ATX code matches:
Xymelin Eco

Xymelin

Nazivin

Galazolin

Lazorin

Nazivin Sensitive for children

Otrivin

Naphthyzin

Sanorin

Knoxprey

For the nose

Lazolvan Rino

Afrin

Eucazoline Aqua

Rinazolin

Grippostad Reno

Farmazolin

Xylometazoline

Nazol Advance

Nazol Baby

Nosolin , Olint , Otrivin , Farmazolin , Tizin , Espazolin , Eucasalin Aqua , Rinostop , Ximelin Eco , Ximelin .

Contraindications

Rhinorus nasal drops are contraindicated for:

• hypertension;
• tachycardia;
• severe atherosclerosis ;
• thyrotoxicosis;
• atrophic pharyngitis;
• increased sensitivity;
• glaucoma;
• up to 2 years of age (for any form and concentration of the drug).

Side effects

With prolonged use, local reactions occur - dryness, burning, irritation of the mucous membrane, tingling, sneezing, and much less often - swelling of the nasal mucosa.

Possible systemic reactions: headache, tachycardia , cardiac arrhythmia , increased blood pressure, vomiting, blurred vision, insomnia , anxiety, depression (when using high doses for a long time).