Compound
1 milliliter of syrup contains:
- fenspiride hydrochloride – 2 milligrams (active ingredient);
- methyl parahydroxybenzoate (E 218) – 0.9 milligrams;
- propyl parahydroxybenzoate (E 216) – 0.35 milligrams;
- vanilla flavoring – 4 milligrams;
- glycerol (E 422) – 22.5 milligrams;
- sunset yellow dye (E 110) – 0.1 milligrams;
- sucrose – 600 milligrams;
- potassium sorbate (E 202) – 1.9 milligrams;
- honey flavoring – 2.5 milligrams;
- sodium saccharinate (E 954) – 0.45 milligrams;
- citric acid monohydrate (E 330) – 0.2 milligrams;
- purified water - up to 1 milliliter.
Bronchipret® syrup - instructions
Registration number: LS-000181 Trade name: Bronchipret® International non-proprietary or generic name: Common ivy leaf extract + Thyme herb extract Dosage form: syrup
Composition (per 100 g of syrup): Active components: Thyme1 herbal extract liquid3 15.0 g Ivy2 leaves extract liquid4 1.5 g Excipients: maltitol syrup, potassium sorbate, citric acid monohydrate, purified water.
1 - Latin name - Thymus vulgaris L., family Lamiaceae or T. Zygus Loefl ex L. family Lamiaceae or a mixture of both species 2 - Latin name - Hedera helix, family Araliaceae 3 - (1 :2-2.5), extractant - mixture: ammonia solution 10% - glycerin 85% - ethanol 90% (volume ratio) - water in the ratio 1:20:70:109 4 - (1:1), extractant - ethanol 70% (v/v)
Description Transparent liquid of light brown color with a characteristic odor. Slight opalescence may occur during storage.
Pharmacotherapeutic group Expectorant of plant origin. ATX code: R05CA10
Pharmacological properties The drug has an expectorant, anti-inflammatory, secretolytic, bronchodilator effect, helps reduce the viscosity of sputum and accelerate its evacuation.
Indications for use As an expectorant in the complex treatment of acute and chronic inflammatory diseases of the respiratory tract, accompanied by cough and sputum formation (tracheitis, tracheobronchitis, bronchitis).
Contraindications Hypersensitivity to any component of the drug, to other plants of the Araliaceae and/or Lamiaceae family, as well as to birch, wormwood, celery; sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption; pregnancy, breastfeeding period; children's age (up to 1 year). Due to the presence of ethanol, it is not recommended to prescribe the drug for alcoholism, epilepsy, liver diseases, brain diseases, and traumatic brain injury.
With caution : Diseases of the gastrointestinal tract (gastritis, gastric ulcer). Before starting to use the drug, you should consult your doctor.
Use during pregnancy and breastfeeding The use of the drug during pregnancy and breastfeeding is contraindicated.
Method of administration and dosage The drug is prescribed orally, after meals. Children from 1 year to 2 years - 2.2 ml 3 times a day; children from 2 years to 6 years - 3.2 ml 3 times a day; children from 6 years to 12 years - 4.3 ml 3 times a day; children over 12 years old and adults - 5.4 ml 3 times a day. It is recommended to take undiluted Bronchipret® syrup with water. Dosing of the drug is carried out using the supplied measuring cup. The course of treatment is 10-14 days. Increasing the duration and conducting repeated courses of treatment is possible on the recommendation of a doctor. If there is no improvement during treatment, or symptoms worsen, or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, method of administration and in the doses indicated in the instructions.
Side effects In rare cases (more than 1/10000, but less than 1/1000), allergic reactions are possible. Adverse reactions whose frequency is unknown, e.g. cannot be assessed based on available data: hypersensitivity reactions such as shortness of breath, urticaria, swelling of the face, mouth and/or pharynx. Infrequently (more than 1/1000, but less than 1/100) gastrointestinal disorders (cramping pain, nausea, vomiting) may occur. In case of the first signs of the reactions described above or other adverse reactions not listed in the instructions for use, you should stop taking the drug and consult a doctor.
Overdose In case of overdose, pain in the stomach, vomiting, and diarrhea are possible. Treatment is symptomatic.
Interactions with other drugs Bronchipret® syrup should not be used simultaneously with antitussive drugs, as well as drugs that reduce the formation of sputum, as this makes it difficult to cough up liquefied sputum. Combination with antibacterial drugs is possible.
Special instructions If, when using the drug for 10–14 days, the symptoms of the disease persist, or shortness of breath, fever or sputum with pus appears, you should consult a doctor. The drug contains 6-7% ethanol (volume). The maximum recommended single dose of the drug for adults, 5.4 ml, contains 0.297 g of absolute ethyl alcohol, the maximum daily dose (16.2 ml) contains 0.891 g of absolute ethyl alcohol. The drug should be prescribed with caution to children (due to the possible negative effects of ethanol). Information for patients with diabetes: the recommended single dose of the drug for adults, 5.4 ml, contains about 0.18 bread units (XU). During storage of the drug, slight turbidity or slight precipitation may occur, which does not affect its effectiveness. Shake before use!
Effect on the ability to drive vehicles and machinery During the period of use of the drug, care must be taken when performing potentially hazardous activities that require increased concentration and speed of psychomotor reactions (driving vehicles, working with moving mechanisms, working as a dispatcher, operator).
Release form : Syrup. 50 or 100 ml in a dark glass bottle with a dosing device, a blue screw cap with a safety ring and a measuring cup on top. Each bottle is placed in a cardboard box along with instructions for use.
Storage conditions Store in the original packaging (dark glass bottle, cardboard box), at a temperature not exceeding 25°C. Keep out of the reach of children!
Shelf life: 3 years. Do not use after expiration date. Opened bottles can be used for 6 months.
Conditions of release Dispensed without a prescription.
Manufacturer Bionorica SE, Kerschensteinerstrasse 11-15, 92318, Neumarkt, Germany
Organization accepting consumer complaints Limited Liability Company "Bionorika" 119619 Moscow, 6th st. New Gardens, 2, bldg. 1. tel./fax, email address
Indications for use
Treatment of symptoms of lower and upper respiratory tract diseases:
- chronic bronchitis with respiratory failure;
- respiratory disorders due to whooping cough , influenza , measles ;
- bronchospastic syndrome;
- bronchial asthma;
- sinusitis;
- nasopharyngitis;
- rhinotracheobronchitis;
- otitis;
- laryngitis.
Instructions for use Sirespa (Method and dosage)
Take the drug orally before meals. The recommended dose is 4 milligrams of fenspiride/kg per day. The dose must be divided into several doses.
Adults and adolescents should take 9-18 scoops of syrup per day (this is 45-90 milliliters of syrup or 90-180 milligrams of fenspiride hydrochloride, respectively).
Siresp syrup, instructions for use for children
- Children under 10 kg should be given 2-4 scoops of syrup per day (this is 10-20 milliliters of syrup or 20-40 milligrams of fenspiride hydrochloride, respectively). Siresp syrup is prescribed for children from two years of age.
- For children weighing more than 10 kg, the dose is 6-12 scoops of syrup (this is 30-60 milliliters of syrup or 60-120 milligrams of fenspiride hydrochloride, respectively).
Siresp 0.2 mg/ml 150 ml syrup
Siresp 0.2 mg/ml 150 ml syrup
Compound. 1 ml of syrup contains: active ingredient: fenspiride hydrochloride 2 mg, excipients: methyl parahydroxybenzoate (E 218), propyl parahydroxybenzoate (E 216), potassium sorbate (E 202); glycerol (E 422), sodium saccharinate (E 954), sucrose, vanilla flavor, honey flavor, orange yellow dye (E 110), citric acid monohydrate (E 330), purified water.
Pharmachologic effect. Fenspiride counteracts bronchoconstriction and has an anti-inflammatory effect. This action is the result of the interaction of various interrelated mechanisms: - antagonistic activity at the level of histamine Hi-receptors and papaverine-like (myotropic) antispasmodic effect; - anti-inflammatory effect is the result of a decrease in the production of various pro-inflammatory factors (cytokines, TNF^a, arachidonic acid derivatives and free radicals), some of which also have a bronchoconstrictor effect. However, these effects were observed only at very high doses or concentrations. After oral administration, the maximum serum concentration of fenspiride is achieved on average from 0.5 hours to 8 hours. The half-life is approximately 12 hours. Fenspiride is excreted mainly through the kidneys.
Indications for use. Symptomatic treatment of respiratory tract diseases (cough and expectoration). Taking this drug should not delay the initiation of antibiotic therapy if necessary.
Contraindications. Hypersensitivity to the active substance and/or to any excipient of the drug. Children under 2 years of age. Siresp contains sucrose, so patients with rare genetic disorders associated with fructose intolerance, poor glucose-galactose absorption syndrome, or sucrase-isomaltase deficiency should not take Siresp.
Pregnancy and lactation period. It is not recommended to take Siresp during pregnancy. There is no data indicating that fenspiride passes into mother's milk, but it is not recommended to take the drug during breastfeeding.
Directions for use and dosage: Take orally before meals. Children over 2 years of age: The usual recommended dose is 4 mg fenspiride hydrochloride/kg per day. Up to 10 kg: 2-4 scoops (or 10-20 ml) Siresp syrup (20-40 mg fenspiride hydrochloride) per day. More than 10 kg: 6-12 scoops (or 30-60 ml) of Siresp syrup (60-120 mg fenspiride hydrochloride) per day, the dose must be divided into several doses. Adults and adolescents: 9-18 scoops (or 45-90 ml) of Siresp syrup per day (90-180 mg of fenspiride hydrochloride) per day, the dose must be divided into several doses. The package includes a measuring spoon with a scale of 1.25 ml, 2.5 ml and 5 ml of syrup. The duration of treatment is determined by the attending physician. 5 ml of syrup contains 10 mg of fenspiride hydrochloride and 3 g of sucrose (equivalent to 0.25 bread units).
Side effect. Cardiac disorders. Rare: moderate tachycardia, which stops when the dosage is reduced. From the digestive system. Common: nausea, stomach pain, gastrointestinal disorders. Unknown: diarrhea, vomiting. Allergic reactions. Rarely: erythema, angioedema, fixed erythema pigmentosa, rash; Due to the presence of para-hydroxybenzoate in the syrup, urticaria may develop. Nervous system disorders. Rare: drowsiness. Unknown: dizziness. Any side (unusual) effects, including those not listed in the package insert, should be reported to your doctor.
Overdose. In case of overdose, the following may occur: drowsiness or agitation, nausea, vomiting, tachycardia. Treatment: gastric lavage, ECG monitoring. Interaction with other medicinal products The interaction of fenspiride with other medicinal products is unknown. However, taking into account the antihistamine effect of fenspiride, one can expect interaction with: - barbiturates - other antihistamines, analgesics, narcotics, sedatives, MAO inhibitors, alcohol.
Features of application. If the disease is infectious, treatment with Siresp is carried out along with standard antibiotic therapy. The drug may cause allergic reactions (delayed reactions are possible) due to the content of preservatives - methyl and propyl parahydroxybenzoate. 5 ml of syrup contains 3 g of sucrose, which must be taken into account when prescribing it to patients with diabetes. The medicinal product contains sunset yellow dye, which can cause allergic reactions (delayed reactions are possible). Influence on the ability to drive vehicles and operate machinery. No studies have been conducted on the effects of Siresp syrup on the ability to drive vehicles and operate machinery.
Release form: 150 ml of syrup in dark plastic bottles, sealed with a polyethylene screw cap with a guarantee ring. The bottle with the leaflet and measuring spoon is placed in a cardboard box.
Storage conditions. In original packaging to protect from light at temperatures not exceeding 25°C. Keep out of the reach of children. Shelf life: 3 years.
Conditions for dispensing from pharmacies. On prescription.
Analogs
Level 4 ATC code matches: Daxas
Inspiron
Erespal
Siresp and Erespal have almost the same composition, so they are considered the most famous analogues of each other. Often people are faced with a choice: buy Siresp or Erespal ? The difference between Sirespa and Erespal is that the first contains dyes and other additives that make it more palatable, while Erespal contains honey and other natural ingredients.
Cough syrup with cyanosis and licorice 250ml No. 1
Name
Cough syrup with blues and licorice.
Release forms
Syrup.
FTG
Expectorant of plant origin.
general characteristics
A thick, yellow-brown liquid with a peculiar odor and bitter taste. During storage, sediment may form.
Compound
Per 100 million 250 ml Active ingredients: Thick licorice root extract (DER: 4-4.5:1, extractant - water) 2 g 5 g Sinyuki rhizomes with roots liquid extract (DER: 1:4, extractant - ethyl alcohol 70%) 7 g 17.5 g Excipients: White crystalline sugar 60 g 150 g Purified water up to 100 ml up to 250 ml The medicine contains at least 5.0% ethyl alcohol.
Pharmacotherapeutic group
Medicines used for coughs and colds. Expectorants.
Indications for use
As an expectorant in the complex therapy of acute respiratory diseases. The scope of application of the medicinal product is based solely on the experience of traditional long-term use of the herbal components included in its composition.
Directions for use and doses
Apply orally 2-3 times a day, 5-10 ml of syrup per x/g glass of water. The course of treatment is 7-14 days. The duration of the course of treatment is determined by the doctor, taking into account the characteristics of the disease, the achieved effect and tolerability of the drug. If during treatment the symptoms of the disease continue for more than 3 days, it is recommended to consult a doctor. If the next dose of the drug was missed, then you should not increase the next dose, but continue to use the drug at the dose recommended by the doctor.
Side effect
Like all medicines, Licorice and Blue Cough Syrup can cause side effects, although not everyone gets them. The following adverse reactions have been registered: frequency unknown - based on the available data, the frequency of occurrence cannot be determined - allergic reactions due to individual intolerance to the components of the drug, pseudoaldosteronism (hypokalemia, hyponatremia, hypertension, edema) with long-term use (more than 4-6 weeks) or excessive overdose of the drug, functional disorders of the heart, myopathy and myoglobinuria, dyspeptic symptoms (diarrhea).
Reports of adverse reactions
If you experience any unwanted reactions, consult your doctor. This recommendation applies to any possible adverse reactions, including those not listed in the package insert. You can also report adverse reactions to the Adverse Drug Events Information Database, including reports of drug failure. By reporting side effects, you can help provide more information about the safety of your drug.
Contraindications
Hypersensitivity to the components of the drug. Liver and/or kidney diseases, arterial hypertension, diseases of the cardiovascular system, hypokalemia, alcoholism, brain diseases with a decrease in the seizure threshold, epilepsy, diabetes mellitus, congenital fructose intolerance, glucose-galactose malabsorption, sucrase-isomaltase deficiency, childhood ( up to 18 years), pregnancy and lactation.
Overdose
Symptoms of an overdose of licorice root are fluid retention in the body, hypokalemia, arterial hypertension, cardiac arrhythmias, hypertensive encephalopathy, hypernatremia, edema, myoglobinemia due to the mineralocorticoid (aldosterone-like) effect of licorice saponins; hypokalemic metabolic alkalosis, hypokalemic rhabdomyolysis, acute renal failure, deposition of calcium salts with damage to bones and heart muscle/calcification of the skeleton and myocardium (as a consequence of rhabdomyolysis). If symptoms of overdose develop, it is recommended to consult a doctor. Treatment is symptomatic.
Precautionary measures
The safety and effectiveness of the drug in children have not been established. Due to the lack of sufficient data, it is not recommended to take the drug for children and adolescents under 18 years of age. If while taking the drug the symptoms of the disease persist or the condition worsens (breathing problems appear, the temperature rises, a cough with purulent sputum appears), you should consult a doctor. Patients taking licorice root should not take other products containing licorice due to the risk of serious adverse reactions (fluid retention, hypokalemia, hypertension, cardiac arrhythmias). Since the syrup has a laxative effect, it should be used with caution in the presence of diarrhea. The syrup should not be taken by patients with fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency. The syrup contains sugar; the drug should not be taken by patients with diabetes. The presence of sugar can cause harm to teeth if taken for 2 weeks or more. This medicinal product contains at least 5.0% ethanol (alcohol), that is, from 197.3 mg to 394.4 mg per dose (5-10 ml), which is equal to 5 - 10 ml of beer, 2.1 - 4. 2 ml wine per dose. Harmful for persons with alcoholism. There is evidence that concomitant use of tobacco is associated with licorice toxicity. When storing the syrup, a slight sediment may appear, since the medicine contains herbal components. It is necessary to shake before use.
Impact on the ability to drive vehicles and operate machinery
The drug contains ethyl alcohol! During the treatment period, it is necessary to refrain from driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Interaction with other drugs
Concomitant use of the drug with thiazide diuretics increases the risk of developing hypokalemia. Combined use is not recommended. When used simultaneously with cardiac glycosides, antiarrhythmic drugs, and corticosteroids, hypokalemia may increase; joint use with these drugs is not recommended. The simultaneous use of other medications containing ethyl alcohol should be avoided. Interactions associated with the presence of ethyl alcohol in the composition: - drugs that cause a disulfiram-like reaction (feeling of heat, redness of the skin, vomiting, tachycardia) when taken together with alcohol: disulfiram, cefamandole, cefoperazone, latamoxef, chloramphenicol, chlorpropamide, glibenclamide, glipizide , tolbutamide and other hypoglycemic drugs, griseofulvin, metronidazole, ornidazole, tinidazole, ketoconazole, procarbazine. -medicines that inhibit the functions of the central nervous system. The simultaneous use of syrup with drugs that reduce the formation of sputum and antitussive drugs of central and peripheral action is not recommended, since, by suppressing the cough reflex, they slow down the release of secretions from the airways, worsen the aerodynamics of the respiratory tract and the processes of oxygenation of the lungs. Licorice root may reduce the effect of antihypertensive medications. It is not recommended to use concomitantly with laxatives, as this may aggravate electrolyte imbalance. If you are taking other medications at the same time, you should consult your doctor.
Storage conditions
Common list. In a place protected from light at a temperature not exceeding 25 °C. Keep out of the reach of children.
Best before date
2 years. Do not use after expiration date. After opening the bottle, the syrup is usable for three months.
Vacation conditions
Over the counter.
Package
Bottles or vials of 100 ml with insert leaflet in packaging No. 1. Bottles or vials of 250 ml with insert leaflet in packaging No. 1.
Buy Cough syrup with cyanosis and licorice d/vn.prim.in bottle or flask 250ml in pack No. 1 in the pharmacy
Price for Cough syrup with cyanosis and licorice d/vn.prim. in bottle or fl. 250 ml in pack No. 1
Instructions for use for cough syrup with cyanosis and licorice d/in. in bottle or fl. 250 ml in pack No. 1
