Buy Amoxiclav powder for the preparation of oral suspension 250mg+62.5mg/5ml 100ml in pharmacies

19:46:41 — 12.01.2022

A fairly strong and almost universal antibacterial drug Amoxiclav contains a semi-synthetic drug ( amoxicillin

), as well as clavulanate (
clavulanic acid
), which is actively involved in the formation of beta-lactamases.
Due to its wide spectrum of activity, it is used for a variety of bacterial diseases. However, despite its effectiveness, the price of Amoxiclav
is somewhat high.
Therefore, we will try to understand the composition and purpose of the drug, and also determine the existing analogues of Amoxiclav
, what is their cost and effect on the body

Composition of Amoxiclav

• Amoxiclav 250 mg/125 mg tablets contain the active ingredients amoxicillin (trihydrate form) and clavulanic acid (potassium salt form). The tablets also contain auxiliary components: MCC sodium croscarmellose.
• Amoxiclav 2X 625 mg and 1000 mg tablets contain the active ingredients amoxicillin and clavulanic acid, as well as additional components: anhydrous colloidal silicon dioxide, flavorings, aspartame , yellow iron oxide, talc, hydrogenated castor oil, silicated MCC.
• Amoxiclav Quiktab 500 mg and 875 mg tablets contain the active ingredients amoxicillin and clavulanic acid, as well as additional components: anhydrous colloidal silicon dioxide, flavorings, aspartame, yellow iron oxide, talc, hydrogenated castor oil, silicated MCC.
• The powder from which the Amoxiclav suspension is prepared also contains amoxicillin and clavulanic acid, and also contains sodium citrate, MCC, sodium benzoate, mannitol, and sodium saccharin as inactive components.
• The powder for preparing Amoxiclav IV infusion contains amoxicillin and clavulanic acid.

Sumamed or Amoxiclav

Sumamed and Amoxiclav are drugs with different active ingredients.

Sumamed contains azithromycin, a macrolide antibiotic that has similar indications for use, but a different mechanism of pharmacological action.

Both medications can provoke the development of dyspeptic disorders. Amoxiclav often causes the development of allergic reactions and can also negatively affect the central nervous system.

Among the advantages of Sumamed, one can note a shorter course of treatment (in some cases, one or three times the use of tablets is sufficient).

This is due to the ability of the active substance to accumulate in peripheral tissues and penetrate directly into the site of the inflammatory reaction. The cost of Sumemad exceeds the price of Amoxiclav.

Release form

The drug is produced in the form of tablets:

• Amoxiclav 250 mg/125 mg – film-coated tablets, package contains 15 pieces.
• Amoxiclav 2X (500 mg/125 mg; 875 mg/125 mg) - coated tablets; the package may contain 10 or 14 pieces.
• Amoxiclav Quiktab (500 mg/125 mg; 875 mg/125 mg) is available in the form of dispersed tablets, 10 such tablets per package.

The product is also produced in the form of a powder from which a suspension is made; the bottle contains powder for preparing 100 ml of the product.

A powder is also produced, from which a solution is made, which is administered intravenously. The bottle contains 600 mg of the product (amoxicillin 500 mg, clavulanic acid 100 mg), 1.2 g bottles are also available (amoxicillin 1000 mg, clavulanic acid 200 mg), the package contains 5 bottles.

pharmachologic effect

The abstract provides information that the antibiotic Amoxiclav (INN Amoksiklav) is a broad-spectrum agent. Group of antibiotics: broad-spectrum penicillins. The medicine contains amoxicillin (semi-synthetic penicillin) and clavulanic acid (β-lactamase inhibitor). The presence of clavulanic acid in the composition of the drug ensures the resistance of amoxicillin to the action of β-lactamases produced by microorganisms.

The structure of clavulanic acid is similar to beta-lactam antibiotics, this substance also has an antibacterial effect. Amoxiclav is active against strains that demonstrate sensitivity to Amoxicillin. These are a number of gram-positive bacteria, aerobic gram-negative bacteria, gram-positive and gram-negative anaerobes.

Amoxiclav or Amoxicillin – which is better?

Amoxicillin is a single-component drug, while Amoxiclav additionally contains clavulanic acid, which increases the stability of amoxicillin and expands the spectrum of action of the drug.

A suitable drug is selected taking into account the pathogen that provokes the pathological process.

Amoxicillin may be less effective against a number of pathogenic microorganisms, most of which have developed resistance to this substance.

Therefore, the drug is practically not used to treat staphylococcal infections, but is prescribed to eliminate streptococci. Amoxiclav is more expensive than Amoxicillin.

Pharmacokinetics and pharmacodynamics

As the Vidal drug reference book informs, after oral administration, both substances are actively absorbed from the gastrointestinal tract; the absorption of the components is not affected by food intake, so it does not matter how you take it - before or after meals. The highest concentration in the blood is observed one hour after the drug was taken. Both active ingredients of the drug are distributed in fluids and tissues. Amoxicillin also enters the liver, synovial fluid, prostate, tonsils, gall bladder, muscle tissue, saliva, and bronchial secretions.

If the membranes of the brain are not inflamed, both active substances do not penetrate through the BBB. At the same time, the active components penetrate the placental barrier and traces of them are detected in breast milk. They bind to blood proteins to a small extent.

In the body, amoxicillin undergoes partial metabolism , clavulanic acid is intensively metabolized. It is excreted from the body through the kidneys; small particles of active substances are excreted by the intestines and lungs. The half-life of amoxicillin and clavulanic acid is 1-1.5 hours.

Which is better Azithromycin or Amoxiclav

Despite the differences in the chemical structure of the active ingredients, both drugs have a similar list of indications for use.

Amoxiclav begins to act faster: after 60 minutes, while azithromycin may take up to 120 minutes.

In some cases, the doctor may prescribe the combined use of these drugs, for example, during complex treatment of hospital-acquired pneumonia.

Unlike Amoxiclav, azithromycin-based drugs are active against:

• Mycoplasmas that provoke atypical pneumonia.
• Koch bacilli, which causes tuberculosis.
• Certain types of Legionella.

If pathogenic microorganisms are resistant to amoxicillin, azithromycin may be the drug of choice.

Indications for use of Amoxiclav

Amoxiclav is prescribed for infectious and inflammatory diseases that develop due to the influence of microorganisms sensitive to this medicine. The following indications for the use of this drug are determined:

• infections of the ENT organs, as well as infectious diseases of the upper respiratory tract ( otitis media , retropharyngeal abscess, sinusitis , pharyngitis , tonsillitis );
• urinary tract infections ( cystitis , prostatitis , etc.);
• infectious diseases of the lower respiratory tract (pneumonia, acute and chronic bronchitis
• gynecological diseases of an infectious nature;
• connective and bone tissue infections;
• infectious diseases of soft tissues, skin (including consequences of bites);
• biliary tract infections (cholangitis, cholecystitis );
• odontogenic infections.

What else Amoxiclav helps with, you should ask a specialist during an individual consultation.

Amoklav Pharmland tablets p/o 875mg/125mg No. 7x2

Name

Amoclav Pharmland 875 mg/125 mg.

Release forms

pills

INN

Amoxicillin+clavulanic acid

FTG

Antibacterial agents for systemic use. Beta-lactam antibiotics, penicillins. Combinations of penicillins, including beta-lactamase inhibitors. ATC code J01CR02.

Description

Tablets are white or almost white, capsule-shaped, scored on both sides, coated. Marbling is allowed on the surface of the tablets.

Compound

Each tablet contains: active ingredients: amoxicillin (in the form of amoxicillin trihydrate) – 875.0 mg, clavulanic acid (in the form of potassium clavulanate 1:1) – 125.0 mg; excipients: sodium starch glycolate (type A), magnesium stearate, colloidal anhydrous silicon dioxide, microcrystalline cellulose, Tabcoat TC-1709 MB white (hydroxypropyl methylcellulose, propylene glycol, ethylcellulose, talc, titanium dioxide), talc, propylene glycol, dimethicone.

Pharmacological properties

This drug belongs to the group of beta-lactam antimicrobial agents and is a combination of semi-synthetic penicillin with a beta-lactamase inhibitor for systemic use. Suppresses the growth of microorganisms that cause infections. ATC code J01CR02.

Indications for use

Treatment of infections caused by microorganisms sensitive to it in adults and children. Acute bacterial sinusitis; Acute otitis media; Exacerbation of chronic bronchitis; Community-acquired pneumonia; Cystitis; Pyelonephritis; Infections of the skin and soft tissues, incl. cellulitis, insect bites, severe dental abscess with spreading cellulitis; Infections of bones and joints, incl. osteomyelitis. Contraindications Hypersensitivity to amoxicillin and/or clavulanic acid; excipients included in this medicinal product. A history of severe immediate hypersensitivity reaction to the administration of other beta-lactam antibiotics (including cephalosporins, carbapenems, monobactams). A history of cholestatic jaundice or impaired liver function that developed during the use of a combination of amoxicillin and clavulanic acid.

Directions for use and recommended doses

Amoclav-1000 is taken orally at the beginning of a meal to minimize gastrointestinal disturbances and improve the absorption of amoxicillin/clavulanic acid. Adults and children weighing ≥ 40 kg: Standard dose (for all indications): 1 Amoclav-1000 tablet twice a day. Higher dose (in particular for infections such as acute otitis media, sinusitis, lower respiratory tract infections and urinary tract infections): 1 Amoclav-1000 tablet three times a day. Overweight children

Side effects

To classify the frequency of adverse effects, the following categories are used: very common (>1/10), common (>1/100 to 1/1000 to 1/10000 to

Overdose

If the number of tablets you take per day exceeds the number recommended by your doctor, or your child swallows tablets, consult a doctor or call an ambulance! Stop taking the medicine! An overdose can be manifested by nausea, vomiting, diarrhea and water and electrolyte imbalance. In patients with impaired renal function or when taking large doses, seizures may develop. Control of blood pressure, heart rate. Gastric lavage and taking antacids are recommended as first aid.

Precautions and special instructions

Allergic reactions, including life-threatening ones, may occur, especially with hypersensitivity to beta-lactam antibiotics and in persons with atopy. Before starting therapy with Amoclav-1000, you must inform your doctor about hypersensitivity to penicillins or cephalosporins in the past. Measles-like rashes have been reported in patients suspected of having infectious mononucleosis receiving amoxicillin. With long-term treatment, the development of microorganisms resistant to the drug Amoclav-1000 is possible. Inform the doctor about the lack of effect of treatment. Appropriate adjustment of therapy is necessary. The appearance of pustules on erythematous areas of the skin with fever at the beginning of treatment may be a symptom of acute generalized exanthematous pustulosis. The occurrence of this adverse reaction requires discontinuation of the drug and is a contraindication to further use of amoxicillin. The amoxicillin/clavulanic acid combination should be used with caution in patients with signs of liver failure. It is possible to develop antibiotic-associated colitis, which is observed during therapy with almost all antibacterial agents. This complication can develop to a life-threatening condition. Inform your doctor if you develop diarrhea during or after completing any course of antibiotic therapy! Stop treatment immediately and seek appropriate therapy! Taking drugs that inhibit intestinal motility is contraindicated. In patients receiving a combination of amoxicillin and clavulanic acid, prolongation of prothrombin time has been observed in rare cases. When co-prescribing anticoagulants, appropriate monitoring is necessary, and the dose of the anticoagulant may need to be adjusted. In patients with reduced urine output, crystals in the urine have been observed in very rare cases. When taking high doses, it is necessary to drink enough fluid to ensure excretion of the drug in the urine and prevent crystalluria. In patients with urinary catheters, catheter patency should be checked regularly. When taking anticoagulants simultaneously, proper monitoring of coagulation system parameters is required. Dosage adjustment of oral anticoagulants may be required to achieve the desired therapeutic effect. In patients with impaired renal function or when taking high doses, seizures may occur. In patients with renal failure, dose adjustment is required according to the level of insufficiency. During treatment of glycosuria, glucose levels should be assessed using enzymatic methods with glucose oxidase, as other methods may give false-positive results. It is possible to obtain false-positive laboratory results when performing a Coombs test or enzyme-linked immunosorbent assay (ELISA). Positive test results in patients taking Amoclav-1000 should be interpreted with caution and confirmed by other diagnostic methods.

Pregnancy and lactation

Pregnancy Animal studies have not revealed any direct or indirect effects of the combination of amoxicillin and clavulanic acid on pregnancy, embryonic/fetal development, childbirth or postpartum development of the fetus. Limited data on the use of this drug in pregnant women does not indicate a potential risk of malformations in the fetus. One study in women with premature rupture of membranes found that prophylactic therapy with a combination of amoxicillin and clavulanic acid may be associated with an increased risk of necrotizing enterocolitis in the newborn. You should avoid taking Amoklav-1000 during pregnancy unless your doctor deems it necessary. Lactation Both active substances of the drug pass into breast milk (the effect of clavulanic acid on breast-fed children is not known). Because of this, there is a risk of developing diarrhea or fungal infection of the mucous membranes in breastfed infants, and discontinuation of breastfeeding may be necessary. The possibility of sensitization should be taken into account. The combination of amoxicillin/clavulanic acid can be used during breastfeeding only after a benefit/risk assessment by the attending physician.

Impact on the ability to drive vehicles and operate machinery

No special studies have been conducted, but adverse reactions may occur (allergic reactions, dizziness, convulsions), which may affect the ability to drive vehicles and other mechanisms.

Storage conditions

Store in a place protected from moisture and light at a temperature not exceeding 25°C. Keep out of the reach of children.

Best before date

2 years. Do not use the medicine after the expiration date.

Vacation conditions

By doctor's prescription.

Package

7 tablets in a contoured, cell-free foil/foil package. 2 or 3 contour cellless packages together with an insert leaflet in secondary packaging.

Manufacturer information

Belarusian-Dutch joint venture limited liability company "Farmland" (JV LLC "Farmland"), Republic of Belarus, Nesvizh, st. Leninskaya, 124 - 3; tel/fax (017) 262-49-94.

Buy Amoklav Farmland tablets p/o 875mg/125mg No. 7x2 in the pharmacy

Price for Amoklav Pharmland tablets p/o 875mg/125mg No. 7x2

Instructions for use for Amoklav Pharmland tablets p/o 875 mg/125 mg No. 7x2

Contraindications

When determining why tablets and other forms of the drug help, you should also take into account existing contraindications:

• Infectious mononucleosis;
• previous liver disease or cholestatic jaundice when taking clavulanic acid or Amoxicillin;
• lymphocytic leukemia;
• high sensitivity to antibiotic drugs from the group of cephalosporins, penicillins, as well as other beta-lactam antibiotics;
• high sensitivity to the active components of the drug.

It is prescribed with caution to people suffering from liver failure and people with severe kidney disease.

Klacid or Amoxiclav

Klacid is a drug based on clarithromycin, which is well tolerated by patients, quickly distributed in tissues and body fluids, accumulating to a greater extent in tissue areas.

Can be used in the treatment of patients with impaired renal function. Unlike Amoxiclav, it has a more convenient dosage regimen and a wider spectrum of action.

Macrolides can provoke the development of adverse reactions in the form of sleep disturbances, increased anxiety, irritability, and hearing impairment. Both medications have similar indications for use; Klacid is additionally prescribed to patients with gastric ulcers.

Side effects

When taking this antibiotic, patients may experience the following side effects:

• Digestive system: loss of appetite, vomiting, nausea, diarrhea ; in rare cases, abdominal pain and liver dysfunction may occur; isolated manifestations - hepatitis, jaundice, pseudomembranous colitis.
• Hematopoietic system: in rare cases - reversible leukopenia , thrombocytopenia ; in very rare cases - eosinophilia , pancytopenia .
• Allergic manifestations: itching , erythematous rash, urticaria ; in rare cases - anaphylactic shock , exudative erythema, edema , allergic vasculitis; isolated manifestations - Stevens-Johnson syndrome, pustulosis, exfoliative dermatitis.
• Functions of the nervous system: dizziness , headache ; in rare cases - convulsions, anxiety, hyperactivity, insomnia .
• Urinary system: crystalluria , interstitial nephritis .
• In rare cases, superinfection may occur.

It is noted that such treatment, as a rule, does not provoke significant side effects.

Principles of treatment

A person becomes infected with a viral infection through the mucous membranes of the eyes and nasopharynx. The incubation period lasts about a week. At this time, symptoms may occur in the form of aches and malaise. During the acute phase, the temperature rises, headaches, cough, runny nose, chills, and nausea appear. The severe phase of the disease causes severe shortness of breath, pain in the abdomen and chest. To prevent serious complications, it is important to quickly and correctly select treatment.

There is currently no vaccine for coronavirus. The course of treatment is based on the use of antiviral medications and antibiotics. The patient is prescribed a potent drug. An antiviral substance will not be able to cope with the virus on its own, so additional painkillers, antipyretics and sorbent medications are taken.

Antibiotics are prescribed for a complicated form of the disease, when opportunistic microflora multiply.

Instructions for use of Amoxiclav (Method and dosage of Amoxiclav for adults)

Medicine in tablets is not prescribed to children under 12 years of age. When prescribing the drug, it should be taken into account that the permissible dose per day of clavulanic acid is 600 mg (adults) and 10 mg per 1 kg of weight (child). The permissible daily dose of amoxicillin is 6 g for an adult and 45 mg per 1 kg of weight for a child.

The agent for parenteral administration is prepared by dissolving the contents of the vial in water for injection. To dissolve 600 mg of the product, you need 10 mol of water, to dissolve 1.2 g of the product - 20 ml of water. The solution should be administered slowly over 3-4 minutes. The intravenous infusion should continue for 30-40 minutes. The solution must not be frozen.

Before anesthesia, to prevent purulent complications, 1.2 g of drugs should be administered intravenously. If there is a risk of complications, the drug is administered intravenously or taken orally in the period after surgery. The duration of the appointment is determined by the doctor.

Amoxiclav tablets, instructions for use

As a rule, adults and children (who weigh more than 40 kg) receive 1 tablet every eight hours. (375 mg), provided the infection is mild or moderate. Another acceptable treatment regimen in this case is to take 1 tablet every 12 hours. (500 mg+125 mg). For severe infectious diseases, as well as for infectious diseases of the respiratory tract, taking 1 tablet every eight hours is recommended. (500 mg+125 mg) or taken every 12 hours 1 tablet. (875 mg+125 mg). Depending on the disease, you need to take an antibiotic from five to fourteen days, but the doctor must individually prescribe a treatment regimen.

Patients with odontogenic infections should take 1 tablet every 8 hours. (250 mg + 125 mg) or once 12 hours, 1 tablet. (500 mg + 125 mg) for five days.

People suffering from moderate renal failure are advised to take 1 tablet. (500 mg + 125 mg) every twelve hours. Severe renal failure is a reason to increase the interval between doses to 24 hours.

Amoxiclav suspension, instructions for use

The patient's childhood involves calculating the dose taking into account the child's weight. Before preparing the syrup, shake the bottle well. In two doses you need to add 86 ml of water to the bottle, each time you need to shake its contents well. Please note that the measuring spoon contains 5 ml of product. Prescribed in a dose depending on the age and weight of the child.

Instructions for use Amoxiclav for children

Children from birth to three months are prescribed the drug at the rate of 30 mg per 1 kg of weight (dose per day), this dose should be divided equally and administered at equal intervals. From the age of three months, Amoxiclav is prescribed at a dose of 25 mg per 1 kg of weight, which is similarly divided equally into two administrations. For infectious diseases of moderate severity, the dose is prescribed at the rate of 20 mg per 1 kg of weight, divided into three administrations. For severe infectious diseases, the dose is prescribed at the rate of 45 mg per 1 kg of weight, divided into two doses per day.

Instructions for use Amoxiclav Quiktab

Before taking, the tablet must be dissolved in 100 ml of water (the amount of water may be more). Before taking, you need to stir the contents well. You can also chew the tablet; it is better to take the drug before meals. Adults and children after reaching 12 years of age should take 1 tablet per day. 625 mg 2-3 times a day. For severe infectious diseases, 1 tablet is prescribed. 1000 mg 2 times a day. Treatment should not last more than 2 weeks.

Sometimes a doctor may prescribe analogues of the drug, for example, Flemoclav Solutab , etc.

Amoxiclav for sore throat

The drug Amoxiclav for angina for an adult is prescribed 1 tablet. 325 mg once every 8 hours. Another treatment regimen involves taking 1 tablet once every 12 hours. A doctor may prescribe a higher dose of an antibiotic if the disease in an adult is severe. Treatment of sore throat in children involves the use of a suspension. As a rule, 1 spoon is prescribed (a dosage spoon is 5 ml). The frequency of administration is determined by the doctor, whose recommendations are important to follow. How to take Amoxiclav for children with sore throat depends on the severity of the disease.

Dosage of Amoxiclav for sinusitis

Whether Amoxiclav helps with sinusitis depends on the causes and characteristics of the course of the disease. The dosage is determined by the otolaryngologist. It is recommended to take 500 mg tablets three times a day. How many days to take the medicine depends on the severity of the disease. But after the symptoms disappear, you need to take the drug for two more days.

Suprax from the group of cephalosporins

The Italian pharmaceutical company Menarini Manufacturing Logis produces Suprax in the form of dispersible tablets. This means that they can be used to prepare a solution for oral administration. Unlike traditional tablets, dispersible tablets release the active substance, cefixime, faster. Suprax is a representative of the third generation cephalosporins, which have the following advantages:

• active ingredients penetrate deep into tissues, destroying pathogenic bacteria;

• are broad-spectrum drugs, to the action of which almost all known infectious pathogens are sensitive;
• have a powerful bactericidal effect and quickly disrupt the integrity of bacterial cell membranes.

Which is better, Suprax or Amoxiclav for the treatment of a particular pathology, it is possible to answer after studying the results of laboratory diagnostics. Both drugs quickly cope with the infection. But Suprax is considered a safer remedy.

For adults, the daily dose is 400 mg once a day or 200 mg twice a day, the average duration of the therapeutic course is 7-10 days. Unlike Amoxiclav, negative consequences are less likely to occur after taking Suprax; its list of contraindications is somewhat narrower. But there are also fewer indications for use. For example, their list does not include flux, the treatment of which is often carried out with Amoxiclav tablets.

Fluoroquinolone Levofloxacin

The therapeutic line Levofloxacin consists of tablets and a solution for parenteral administration, as well as eye drops. The drug is included in the clinical and pharmacological group of fluoroquinolones, to the action of which most pathogens have not lost sensitivity. Most often, Levofloxacin is prescribed to patients suffering from infections of the following vital systems:

• genitourinary, including the urogenital tract;

• bronchopulmonary, including the upper and lower respiratory tract;
• skin.

Levofloxacin helps to quickly cope with the painful symptoms of cystitis, pyelonephritis, urethritis and other diseases. It is usually started at a dose of 250 mg, which is increased to 750 mg if necessary. The duration of therapy is individual and varies depending on the clinical situation.

Which is better, Levofloxacin or Amoxiclav, depends on the type of disease diagnosed. The latter has proven itself especially well in the treatment of respiratory bacterial lesions. And Levofloxacin is more often used in the treatment of infections of the bladder, kidneys, and urethra.

Flemoklav Solutab

Flemoklav is produced by the pharmaceutical company Astellas Pharma Europe, BV (Netherlands) in the form of biconvex tablets intended for dissolution in water.

The active substances - amoxicillin and clavulanic acid - are almost not destroyed in the stomach by aggressive hydrochloric acid, but penetrate intact into the small intestine, where they are absorbed into the blood. The closest analogue of Flemoklav is Amoxiclav Kviktab, which is a dispersible tablet. The duration of therapy depends on the severity of the infection, but longer than 14 days the drug is used in exceptional cases.

Adults are prescribed 500/125 mg three times a day or 875/125 mg twice a day. For the treatment of chronic, recurrent, severe infections, this dose is doubled. An analogue of Amoxiclav is the product of the same pharmaceutical company Flemoxin Solutab in the form of tablets for oral administration and preparation of a solution. But there is an important difference - it contains only amoxicillin as an active ingredient. The absence of clavulanic acid makes it less therapeutically effective.

Overdose

To avoid overdose, the prescribed dosage for children and the dosage of Amoxiclav for adults must be strictly observed. It is recommended to carefully study the instructions or watch a video on how to dilute the suspension.

Wikipedia indicates that an overdose of the drug may result in a number of unpleasant symptoms, but there is no data on life-threatening conditions for the patient. , abdominal pain , vomiting , diarrhea may occur . In severe cases, seizures may occur.

If the drug has been taken recently, gastric lavage is performed, activated charcoal . The patient must be monitored by a doctor. In this case, hemodialysis .

Interaction

When taking the drug simultaneously with some drugs, undesirable manifestations may occur, which is why tablets, syrup and intravenous administration of the drug should not be used in parallel with a number of drugs.

The simultaneous use of the drug with Glucosamine , antacids, aminoglycosides, and laxatives slows down the absorption of Amoxiclav; when taken simultaneously with Ascorbic acid , the absorption accelerates.

With simultaneous treatment with Phenylbutazone , diuretics, NSAIDs, Allopurinol and other drugs that block tubular secretion, the concentration of amoxicillin increases.

If anticoagulants and Amoxiclav are taken simultaneously, the prothrombin time increases. Therefore, drugs in such a combination must be prescribed with caution.

Amoxiclav increases the toxicity of Methotrexate when taken simultaneously.

When taking Amoxiclav and Allopurinol , the likelihood of exanthema increases.

You should not take Disulfiram and Amoxiclav at the same time.

Antagonists when taken together are amoxicillin and Rifampicin . The drugs mutually weaken the antibacterial effect.

You should not take Amoxiclav and bacteriostatic antibiotics (tetracyclines, macrolides), as well as sulfonamides at the same time, as these drugs can reduce the effectiveness of Amoxiclav.

Probenecid increases the concentration of amoxicillin and slows down its elimination.

When using Amoxiclav, the effectiveness of oral contraceptives may decrease.

special instructions

Since most people with lymphocytic leukemia and infectious mononucleosis who received Ampicillin subsequently noted the appearance of an erythematous rash, such people are not recommended to take ampicillin antibiotics.

It is prescribed with caution to people with a tendency to allergies .

If a course of treatment with the drug is prescribed for adults or children, it is important to monitor the functions of the kidneys, liver, and the process of hematopoiesis.

People who have impaired renal function need a dose adjustment of the drug or an increase in the interval between taking the drug.

It is optimal to take the product during meals to reduce the likelihood of side effects from the digestive system.

Patients undergoing treatment with Amoxiclav may experience a false positive reaction when determining glucose levels in urine when using Felling's solution or Benedict's reagent .

There is no data on the negative impact of Amoxiclav on the ability to drive vehicles and work with precision machinery.

Patients who are interested in whether Amoxiclav is an antibiotic or not should keep in mind that the product is an antibacterial drug.

It is recommended to drink plenty of water and other liquids during the course of treatment with the drug.

If Amoxiclav is prescribed, the patient's childhood age must be taken into account when prescribing the medication form and dosage.

Taking medications

Not everyone understands whether it is possible to take antibiotics for coronavirus and what symptoms should cause this. It is strictly forbidden to take medications on your own without a doctor’s prescription, since incorrectly selected antibiotics will not only weaken the body, but can also cause death.

Indications for taking antibiotics:

• for several days the body temperature exceeds 38 degrees;
• bacterial microflora develops in the respiratory tract; discharge of green and yellow sputum when coughing is often observed as confirmation of infection;
• with prolonged treatment with antiviral substances, general malaise persists;
• stool contains purulent mucus.

If the patient has all the symptoms, the doctor will not be able to prescribe antibiotics without bacteriological culture. To conduct research, a smear is taken from the trachea and nasopharynx, and the mucous part is removed from the stool. It is inoculated on a nutrient medium to identify the type of infection. After receiving the results, an additional type of antibiotic is determined that can destroy the virus.

If a patient is prescribed a course of antibiotics, this does not mean that antiviral medications do not need to be taken. A complex intake of drugs is prescribed to achieve the optimal effect in order to eliminate the bacterial environment from the gastrointestinal tract or respiratory tract. After completing therapy, all tests are taken from the patient; if coronavirus infection is not confirmed, the patient is discharged.

Analogues of Amoxiclav

Level 4 ATX code matches:
Arlet

Ecoclave

Panclave

Oxamp-Sodium

Oxamp

Amoxicillin + Clavulanic acid

Augmentin

Ampisid

Amoxil K 625

Flemoklav Solutab

Sultasin

There are a number of analogues of this drug. The price of analogues depends, first of all, on the manufacturer of the drug. There are analogues on sale that are cheaper than Amoxiclav. For patients interested in what can replace this antibiotic, experts offer a large list of medications. These are Moxiclav , Co-Amoxiclav , Augmentin , Clavocin , Flemoclav , Medoclav , Baktoklav , Ranclave , Amoviklav , etc. However, any substitute should only be prescribed by a doctor. You can choose a cheaper analogue in tablets, for example, Augmentin. You can also choose a Russian analogue, for example, Amoxicillin .

Flemoklav Solutab and Amoxiclav - the difference between the drugs

The active components of the drugs are similar. The difference between drugs is in the dosage of the active components in the release forms of these drugs. Both drugs fall into approximately the same price category.

Which is better: Amoxiclav or Augmentin?

What is the composition of Amoxiclav and Augmentin , what is the difference between these drugs? Both of these products contain similar active ingredients, that is, in fact they are the same thing. Accordingly, the pharmacological action of the drugs is almost identical, as are the side effects. Only the manufacturers of these drugs differ.

Which is better: Sumamed or Amoxiclav?

Sumamed contains azithromycin, which is a broad-spectrum antibiotic. Before prescribing any of the drugs, it is important to check the sensitivity of the microflora to their action.

Which is better: Flemoxin Solutab or Amoxiclav?

Flemoxin contains only amoxicillin. Accordingly, its spectrum of influence is smaller than that of the drug Amoxiclav, which also contains clavulonic acid .

Suprax or Amoxiclav

Amoxiclav and Suprax (cephalosporin antibiotic) are antibacterial drugs with different composition and mechanism of action.

Suprax is effective in treating patients with chronic obstructive pulmonary disease and is more convenient to use. It is one of the most modern, effective antibiotics, which can be considered as a substitute if Amoxiclav is ineffective.

The advantage of Amoxiclav is the ability to use the medicine in the treatment of children under one year of age.

The drug is better tolerated by some categories of patients and has a smaller list of contraindications and possible side effects.

Reviews about Amoxiclav

In the process of discussing the drug Amoxiclav, reviews from doctors and patients are predominantly positive. It is noted that the antibiotic is effective in the treatment of respiratory tract diseases, and it is suitable for both adults and children. Reviews mention the effectiveness of the product for sinusitis, otitis media, and genital tract infections. As a rule, adult patients take 875 mg + 125 mg tablets; if the dosage is correct, relief occurs quickly. Reviews note that after a course of antibiotic treatment, it is advisable to take drugs that restore normal microflora .

Reviews of the Amoxiclav suspension are also positive. Parents write that it is convenient to give the product to children, as it has a pleasant taste and is normally perceived by children.

Augmentin or Amoxiclav – which is better?

Agumentin is a drug similar to Amoxiclav in composition, dosage, and spectrum of pharmacological activity.

The cost of a course of treatment with Augmentin will cost approximately 5-10% more. Both medications are available in several dosage forms, which allows you to choose the right drug for treating both adults and children.

Indications, contraindications, and possible adverse reactions for the drugs are similar, so Augmentin can be used as a replacement for Amoxiclav.

Particular attention should be paid to the dosage of medications: the quantitative content of the active components of the substitute must completely coincide with the dosage recommended by the doctor.

Amoxiclav price, where to buy

• The price of Amoxiclav tablets 250 mg + 125 mg is on average 250 rubles for 15 pieces. You can buy the antibiotic Amoxiclav 500 mg + 125 mg at a price of 350 – 400 rubles for 15 pcs. How much 875 mg + 125 mg tablets cost depends on the place of sale. On average, their cost is 400 - 500 rubles for 14 pieces.
• Price Amoxiclav Kviktab 625 mg – from 350 rubles for 14 pcs.
• The price of Amoxiclav suspension for children is 300 rubles (100 ml).
• The price of Amoxiclav 1000 mg in Ukraine (Kyiv, Kharkov, etc.) is from 300 hryvnia for 14 pieces.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Amoxiclav powder for suspension.
  for internal approx. 400mg+57mg/5ml 17.5gLek dd RUB 193 order
• Amoxiclav tablets p.p.o. 500mg+125mg 15 pcs. Lek dd

  RUB 213 order

• Amoxiclav powder for suspension. for internal approx. 250mg+62.5mg/5ml 20 doses 25gLek dd

  RUB 273 order

• Amoxiclav Quiktab dispersible tablets 250mg+62.5mg 20 pcs. Lek dd

  RUB 259 order

• Amoxiclav powder for suspension. for internal approx. 400mg+57mg/5ml 35gLek dd

  RUB 286 order

Pharmacy Dialogue

• Amoxiclav tablets 875mg+125mg No. 14Lek

  RUB 297 order

• Amoxiclav Quiktab (dispersible tablet 625 mg No. 14)Lek

  RUB 179 order

• Amoxiclav Quiktab (dispersible tablet 1000 mg No. 14)Lek

  452 rub. order

• Amoxiclav powder for suspension 125mg+31.25mg/5ml 100mlLek

  115 rub. order

• Amoxiclav powder for suspension 400mg+57mg/5ml 140ml(35g)Lek

  RUB 278 order

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Pharmacy24

• Amoxiclav 125 mg/31.25 mg 5 ml 100 ml powder for oral suspension Lek pharmaceutical company d.d., Slovenia
  131 UAH. order
• Amoxiclav 500mg/100mg No. 5 powder for the preparation of solution for injection Sandoz GmbH, Austria

  379 UAH. order

• Amoxiclav Quiktab 875mg/125mg N14 tablets Lek pharmaceutical company d.d. Slovenia / Sandoz Ilac Sanay ve Tikaret A.S., Turecchina

  164 UAH order

• Amoxiclav 2x 875 mg / 125 mg No. 14 tablets Lek pharmaceutical company d.d., Slovenia

  189 UAH order

• Amoxiclav 2S 400 mg/57 mg 5 ml 17.5 70 ml powder for oral suspension Lek pharmaceutical company d.d., Slovenia

  115 UAH order

PaniPharmacy

• Amoxiclav 2 tablets Amoxiclav 2 film-coated tablets 875/125 mg No. 14 Slovenia, Lek

  217 UAH. order

• Amoxiclav Quiktab tablets Amoxiclav Quiktab dispersible tablets 500mg/125mg No. 10 Slovenia, Lek

  87 UAH order

• Amoxiclav bottle Amoxiclav lyophilized powder for injection 1.2g No. 5 Slovenia, Lek

  454 UAH. order

• Amoxiclav liquid Amoxiclav powder for suspension 250mg/62.5mg (312.5mg)/5ml 100ml Slovenia, Lek

  167 UAH order

• Amoxiclav liquid Amoxiclav powder for suspension 125mg/31.25mg (156.25mg)/5ml 100ml Slovenia, Lek

  131 UAH order

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