Antral tablets: instructions for use, price, reviews

Pharmacodynamics and pharmacokinetics

Antral is a hepatoprotector , used for the prevention of hepatitis of various origins and cirrhosis of the liver , eliminates the symptoms of indigestion and asthenovegetative syndrome , normalizes appetite and sleep.

When taken for a long time in courses, the drug reduces the level of bilirubin in the blood, reduces the activity of the enzymes alanine aminotransferase and aspartate aminotransferase . gamma globulins and prothrombin index also return to normal .

The medicine has a long-term analgesic, anti-inflammatory , and immunocorrective effect. Also, the active ingredient of the product reduces body temperature.

Liver cells and hepatocytes begin to recover, and the impact of various toxic substances on the body decreases. of antioxidant is activated .

The drug does not accumulate in the body, does not irritate the esophagus and intestines, and does not affect immune processes. The product is not teratogenic and not embryotoxic .

Thanks to the enteric coating, after administration the maximum concentration of the active substance is reached after 3.5 hours. The drug is removed from the body through the gastrointestinal and urinary system within five hours.

Pharmacological properties of the drug Antral

Antral (tris-[N(2,3-dimethylphenyl) anthranilato]aluminum) belongs to the group of hepatoprotectors. Effective in the treatment of acute and chronic hepatitis of various origins, liver cirrhosis, helps reduce the severity of asthenovegetative disorders, improves appetite, sleep, and reduces dyspeptic symptoms. When used as a course, the drug normalizes the content of bilirubin, γ-globulins, blood cholesterol, prothrombin index, transaminase activity and alkaline phosphatase. Antral has a prolonged anti-inflammatory, analgesic, and antipyretic effect. Based on the results of preclinical studies, it was established that Antral, in conditions of acute, subacute and chronic liver damage by various xenobiotics and their combinations, helps to reduce the severity of the consequences of exposure to hepatotoxins, activate reparative processes in hepatocytes and practically normalize indicators of the structural and functional state of the liver. The drug inhibits lipid peroxidation processes in the blood and tissues, supports the activity of the body's antioxidant systems, and stabilizes the structure of the liver and hepatocyte membranes. It does not have a negative effect on the functions of organs and systems of the body, does not have cumulative properties, does not exhibit immunotoxic, locally irritating, allergenic, ulcerogenic, embryotoxic, or teratogenic effects. The maximum concentration of the drug in the blood plasma is reached after 180–250 minutes, the half-life is 4–5 hours. It is excreted in urine and feces.

Indications for use

The medicine is prescribed:

for the treatment of acute viral, toxic, drug-induced, allergic and alcoholic hepatitis ;
for the treatment of chronic hepatitis ;
with cirrhosis of the liver ;
for the treatment of inflammation in the gastrointestinal tract ;
for fatty liver ;
after cholecystectomy ;
for prevention during chemotherapy and radiation therapy ;
in case of poisoning;
conditions after acute viral hepatitis .

Side effects

As a rule, the drug is well tolerated, side effects are rare.

However, you may experience:

weakness, loss of consciousness, dizziness;
nausea, indigestion , abdominal pain, diarrhea ;
allergies, urticaria , itching and rashes on the skin surface.

After discontinuation of the drug, adverse reactions quickly disappear.

Antral tablets, instructions for use (Method and dosage)

The medicine is taken orally, orally, after meals. The daily dosage is distributed 3 times.

Before starting to take the drug, you should consult your doctor. The duration of therapy and daily dosage should be determined by a specialist.

For liver cirrhosis :

children from 4 to 10 years old are prescribed 0.3 grams per day;
adults: 1.2 grams per day for the first week, 0.6 g per day for the next 2-3 weeks.

In other cases:

children from 4 to 10 years old are prescribed 0.3 grams per day;
children over 10 years old and adults - 0.6 g per day.

The course of treatment usually ranges from 3 weeks to a month. A month later the course is taken again.

Antral 200 mg No. 30 tablets

Trade name: Antral® International nonproprietary name: No Dosage form: Film-coated tablets 0.2 g Composition: One tablet contains the active substance - Antral® in terms of dry matter 100 mg (0.1 g) or 200 mg (0. 2 g), excipients: heavy magnesium carbonate, potato starch, crospovidone XL 10 (Polyplasdone XL 10), microcrystalline cellulose 101, povidone K 29/32, polysorbate-80 (Tween-80), aerosil, calcium stearate, shell composition: Opadry II 85 G 18490 white (polyvinyl alcohol, polyethylene glycol, talc, lecithin, titanium dioxide (E 171)), Opadry II 85 G25557 red (carmoisin aluminum varnish (E 122), FD&C blue #2 aluminum varnish (E 132), iron red oxide (E 172), titanium dioxide (E 171), lecithin, polyethylene glycol, talc, polyvinyl alcohol). Description: Round tablets with a biconvex surface, film-coated, dark red in color. Pharmacotherapeutic group: Drugs for the treatment of liver diseases

Pharmacological properties: Pharmacokinetics The maximum concentration of the drug in the blood is observed 3-4 hours after use, the half-life is 4-5 hours. The drug is excreted in urine and feces.

Pharmacodynamics Antral® belongs to the group of hepatoprotective drugs. Effective in the treatment of acute and chronic hepatitis of various origins, cirrhosis of the liver, helps reduce asthenovegetative disorders, improves appetite, sleep, and reduces dyspeptic symptoms. When used in a course, the drug normalizes the content of bilirubin, β-globulins, cholesterol in the blood, prothrombin index, activity of transaminases (ALAT and AST) and alkaline phosphatase. Antral® has a prolonged anti-inflammatory and analgesic effect. Antral® helps to reduce the effects of hepatotoxins, activate reparative processes in hepatocytes and practically normalize the structural and functional state of the liver. The drug inhibits the processes of lipid peroxidation in the blood and tissues, supports the activity of the body's antioxidant systems, and stabilizes the structure of the liver and hepatocyte membranes. Indications for use: acute and chronic hepatitis of various etiologies (viral, alcoholic, medicinal, toxic) fatty degeneration and cirrhosis of the liver inflammatory diseases of the gallbladder, spleen, pancreas resection of the gallbladder prevention of liver diseases due to the harmful effects of toxins of various etiologies: nutritional toxins, drugs drugs, chemotherapy, radiation therapy. Method of administration and dosage: Antral® is prescribed orally, after meals, 3 times a day: – adults and children over 10 years old – 200 mg per dose; for liver cirrhosis: in the first week of treatment - 400 mg per dose, then 2-3 weeks - 200 mg per dose; – children aged 4-10 years (including those with cirrhosis of the liver) – 100 mg per dose. The duration of treatment depends on the severity of the disease. The average course of treatment is 3-4 weeks. The course of treatment should be repeated after 3-4 weeks. It is recommended to take Antral® 20-30 minutes after meals, with a moderate amount of water. Side effects: The drug is well tolerated by patients. Rarely: - dyspepsia. Contraindications: - impaired renal excretory function - individual hypersensitivity to the components of the drug - pregnancy and lactation - children under 4 years of age Drug interactions: Antral® is well compatible with antibacterial, detoxifying, choleretic, vitamin preparations, which allows it to be included in complex therapy. When used simultaneously in patients with liver cirrhosis, Antral® does not affect the activity of steroid and cytostatic drugs; a reduction (up to 50-70%) of the previously used dose of steroids is allowed without further reducing the effectiveness of treatment. Special instructions: Use in pediatric practice In this dosage form, the drug is not prescribed to children under 4 years of age. Peculiarities of the drug's influence on the ability to drive a vehicle or operate potentially dangerous machinery. The drug does not affect the ability to drive a vehicle or operate potentially dangerous machinery. Overdose: Symptoms: increased side effects. Treatment: the stomach should be rinsed and (if necessary) symptomatic treatment. Release form and packaging: Film-coated tablets 0.2 g. 10 tablets in a blister pack (blister). 3 strip packs (blisters) along with instructions for use in a cardboard box. Storage conditions: Store in a dry place, protected from light, at a temperature not exceeding 25? C. Keep out of the reach of children! Shelf life: 2 years. The drug should not be used after the expiration date indicated on the package. Conditions for dispensing from pharmacies: Without a prescription

Interaction

The drug is compatible with choleretic and antibacterial agents, vitamins detoxification agents .

Note!

The description of the drug Antral on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

Analogs

Level 4 ATC code matches:
Hepatosan

Sirepar

Hepatomax

Phosphogliv

Phosphogliv forte

Thiotriazolin

Karsil Forte

Darsil

Silibor

Karsil

Erbisol

Silimar

Methionine

Remaxol

Enerliv

Laennec

Progepar

Potassium orotate

Legalon

Hepa-Merz

Common analogues: Galstena, Heptox, Glutargin, Glutarsol, Darsil, Larnamin, Karsil, Lesfal, Legalon, Hepa-merz, Hepaforte, milk thistle fruits, Ornitox, Essentiale N, Enerliv .

Reviews for Antral

Reviews for the drug are good, the drug quickly restores liver function, especially if you follow a diet and follow the doctor’s recommendations. Many people like the convenient release form. However, sometimes side effects occur, and pain may intensify during the first stages of treatment. Doctors rarely prescribe Antral. Reviews from doctors about the drug are mixed. The drug helps with long-term use, several courses, most often if the disease is mild.

Why is Antral better in comparison with analogues?

The drug Antral has been on the Ukrainian pharmaceutical market for quite a long time and has managed to prove its effectiveness and safety among patients and doctors. The medicine is always available in the pharmacy chain and in the warehouses of distributors, which ensures its availability.

You can buy the drug Antral in the 911 pharmacy network at an affordable price or on the official website apteka911.ua. There you can also find out about the availability of the drug and its analogues in the nearest pharmacies of the network, book or arrange delivery, thereby protecting your health from infections.

Price for Antral

The price in Ukraine is 75 UAH for 30 tablets, 0.2 grams each.

The price for Antral in Kharkov is approximately 70 UAH for 30 pieces.

The cost of the drug in Odessa is 74 UAH for 30 tablets.

You can buy the medicine in Russia for about 240 rubles, 30 tablets of 0.1 grams each.

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine
Online pharmacies in KazakhstanKazakhstan

LuxPharma* special offer

Antral tab.
0.2g N30 RUR 1,700 order

Pharmacy24

Antral 100 mg No. 30 tablets PAT "Farmak", Ukraine
92 UAH. order
Antral 200 mg No. 30 tablets PAT "Farmak", Ukraine
132 UAH order

PaniPharmacy

Antral tablets Antral film-coated tablets 0.1g No. 30 Ukraine, Farmak OJSC
88 UAH order
Antral tablets Antral film-coated tablets 0.2g No. 30 Ukraine, Farmak OJSC
142 UAH order

Antral

Antral is a drug that affects the liver and helps reduce disturbances in its basic functions.
The product is produced by the Ukrainian company PJSC FARMAK. The active ingredient of Antral in terms of dry matter is 200 mg (0.2 g). Plus additional substances such as magnesium carbonate, crospovidone, calcium stearate, cellulose, potato starch, lecithin. The drug has hepatoprotective and antitoxic effects. The liver is one of the most important organs in the human body. It performs many functions without which we could not live normally. For example, it destroys toxic substances that enter our body with alcohol and food. Other tasks of the liver are maintaining immunity and participating in fat, protein and carbohydrate metabolism in the body. Antral is a drug that helps the liver, normalizes metabolism and prevents the destruction of its cells.