Analogues of Gepatrombin

Compound

The ointment contains the main substances: sodium heparin, prednisolone acetate and lauromacrogol 600 .
Additional components: solid and liquid paraffin, silicon dioxide, lanolin .

Rectal suppositories include the following active ingredients: sodium heparin, prednisolone acetate and lauromacrogol 600.

Additional components: medium chain triglycerides, solid fat, colloidal silicon dioxide, glyceryl tristearate.

Hepatrombin G or Heparin ointment

Manufacturer: NIZHFARM, Green Dubrava, Altaivitamins, Russia
Release form: ointment for external use

Active ingredient: Sodium Heparin + Benzocaine + Benzylnicotinate

Heparin ointment can be safely called an analog cheaper than Hepatrombin G and regular Hepatrombin, since it is effective for thrombophlebitis, injuries, and hemorrhoids.

It has an antithrombotic and local analgesic effect, relieves swelling and inflammation at the sites of application, and is effective for hematomas.

Pharmacodynamics and pharmacokinetics

This combined drug is actively used in proctology, exhibiting antithrombotic, anti-inflammatory and venosclerotic effects.

Its main component, heparin , is a well-known direct-acting anticoagulant. It is also characterized by increasing the ability to regenerate connective tissue and preventing blood in the area of ​​hemorrhoids.

As for prednisolone , which belongs to GCS, it exhibits anti-inflammatory, antiexudative and antiallergic effects, reducing itching and burning sensations, pain in the anorectal area.

Lauromacrogol 400 or polidocanol has a local anesthetic effect, providing sclerosis in the area of ​​hemorrhoids .

Penetrating into the body, Hepatrombin G ointment, like suppositories, undergoes biotransformation in the liver and reticuloendothelial system. Plasma protein binding can reach at least 95%. The drug is excreted through the kidneys in several stages.

pharmachologic effect

Manufacturer: Hemofarm, Serbia.
Release form: cream, gel and ointment for external use

Active ingredient: Heparin + Allantoin + Dexpanthol

Hepatrombin is a combined drug that has local anticoagulant, anti-inflammatory and regenerative effects. Its therapeutic effect consists of the actions of all the components of the drug.

Heparin counteracts the formation of blood clots, swelling and inflammation, and promotes local blood flow. Allantoin stimulates metabolic processes and proliferation in tissues. Dexpanthenol, in addition to being an excellent healing agent, also improves the absorption of heparin.

Contraindications

This drug in any form is not prescribed for:

• bacterial, viral and fungal skin lesions;
• tuberculosis;
• syphilis;
• skin tumors;
• reactions to vaccination;
• early pregnancy ;
• predisposition to bleeding;
• sensitivity to the drug.

Instructions for Gepatrombin G (Method and dosage)

Gepatrombin G ointment instructions for use recommend applying a thin layer to the affected areas until the symptoms of the disease disappear and some more time to consolidate the result. During the main therapy, the ointment can be applied 3 times a day, and then 1 time throughout the week.

The ointment can also be used rectally - inserted into the rectum using the tip, lightly pressing on the tube and squeezing out a little of the drug.

Gepatrombin G suppositories instructions for use recommend administering rectally 1-2 times a day, preferably after defecation.

Analogs

Level 4 ATC code matches:
Girudoproct

Heparoid Zentiva

Heparin ointment

Heparin

Lyoton

Trombless

Venolife

Hepatrombin

The main analogues of this drug: Proctosedyl, Proctosan and Girudoproct.

Reviews of Gepatrombin G

It should be noted that reviews of Gepatrombin G ointment are mainly related to the treatment of hemorrhoids. Usually the drug is used for the resorption of hemorrhoidal cones . This therapy turns out to be very effective and helps to quickly get rid of unwanted symptoms.

You can also find reviews about Hepatrombin G suppositories, but this form of the drug is used by patients somewhat less frequently, although it is no less effective.

In addition, reviews of Gepatrombin G ointment for hemorrhoids report that sometimes it is not used entirely for its intended purpose. For example, this external remedy can be used to resolve hematomas that form after injections. There are cases when the ointment was used by women to eliminate swelling and bags under the eyes.

In addition to reports of the effectiveness of this drug, one can find stories about the development of side effects during improvement. Usually these are allergic reactions in the form of itching, rashes and swelling.

Despite the fact that this drug helps well in some off-label cases, it should not be used on its own. This is especially true during pregnancy, when any treatment requires maximum caution.

Gepatrombin G or Relief – which is better?

Manufacturer: Sagmel, USA
Release form: suppositories and ointment for rectal and external use

Active ingredient: Phenylephrine hydrochloride

Relief contains a vasoconstrictor component, which reduces exudation and swelling of the tissue and relieves itching in the anus.

The Relief analogue is best used for additional symptomatic treatment of hemorrhoids, not instead of Gepatrombin G, but in the complex treatment of hemorrhoids and anal fissures accompanied by anal itching.

Price Gepatrombin G, where to buy

The price of Gepatrombin G in suppositories varies between 220-300 rubles.

You can buy ointment for 180-250 rubles.

The price of Gepatrombin G ointment in Ukraine starts from 50 UAH.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine

ZdravCity

• Gepatrombin G rectal suppositories.
  10 pcs. Hemofarm A.D. Vršac, branch Production site Šabac RUR 314.order
• Gepatrombin G ointment 20g Hemofarm A.D. Vršac, branch Production site Šabac

  RUB 313 order

Pharmacy Dialogue

• Gepatrombin G ointment 20g Hemofarm

  RUR 348 order

• Hepatrombin G suppositories (sup. rect. No. 10) Hemofarm

  360 rub. order

• Hepatrombin gel (tube 50000 units 40 g)Hemofarm

  RUB 259 order

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Analogues of Gepatrombin

Analogues of Hepatrombin are drugs containing Heparin, as well as other components, which allow them to be used for thrombosis and other venous diseases of the lower extremities.

One of the varieties of Hepatrombin is Hepatrombin G, which is used topically for hemorrhoids and other diseases of the anus and rectum.

Substitutes for Hepatrombin G ointment are all kinds of creams, ointments and gels, for example, Proctosedyl, Aurobin, Proctosan. Analogues in suppositories are represented by other drugs, such as Natalsid, Nigepan, Hepazolon, Neo-anuzole.

The table shows the average prices of various analogues of Gepatrombin and Gepatrombin G, depending on the form of release:

Venolife

Manufacturer: AKRIKHIN, Russia
Release form: gel for external use

Active ingredient: Heparin sodium + Dexpanthenol + Troxerutin

Synonyms: Troxevasin Neo

The Venolife analogue, in addition to Heparin and Dexpantol, additionally contains the angioprotector Troxerutin, which reduces the fragility and permeability of capillaries, normalizes microcirculation and tissue nutrition, and reduces congestion in the veins.

Phenylethyl alcohol, added to this analogue as a preservative, additionally has an antiseptic and fungicidal effect.

Troxevasin

Manufacturer: Balkanfarma, Bulgaria
Release form: capsules, gel for external use

Active ingredient: Troxerutin

Synonyms: Troxerutin Vramed, Troxerutin Zentiva, Troxerutin VetProm, Phlebopress

Troxevasin is an analogue of Gepatrombin gel, has angioprotective, venotonic and antioxidant effects, relieves swelling, exudation and inflammation.

The analogue Troxevasin is used for venous insufficiency, both acute and chronic. Effective both at the beginning of the disease and even in the later stages.

Proctosedyl

Manufacturer: Sanofi, India
Release form: ointment, rectal capsules

Active ingredient: Benzocaine + Butamben + Hydrocortisone + Framycetin + Esculoside

The analogue Proctosedyl, due to its combined composition, has an anti-inflammatory, local anesthetic and antipruritic effect. Also active against some microorganisms. Used for hemorrhoids and itching in the anal area.

Aurobin

Manufacturer: Gedeon Richter, Hungary
Release form: ointment for external and rectal use

Active ingredient: Prednisolone capronate + Lidocaine hydrochloride + Dexpanthenol

The Hungarian analogue Aurobin primarily has an anti-inflammatory, anti-edematous and antipruritic effect, thanks to the main component, the glucocorticoid – Prednisolone. Lidocaine has a local anesthetic effect. Dexpanthenol provides a healing effect.

Posterisan

Manufacturer: Dr.
Kade, Germany Release form: ointment and rectal suppositories

Active ingredient: Microbial cells of Escherichia coli killed by phenol

The Posterizan analogue is used rectally in the form of ointments and suppositories not only as an anti-inflammatory and antipruritic, but also as an immunostimulant, thanks to its special composition - inactivated bacteria and their metabolic products.

The analogue increases local tissue resistance to the effects of various microorganisms, normalizes capillary permeability and regenerates damage.

Nigepan

Manufacturer: NIZHFARM, Russia
Release form: rectal suppositories

Active ingredient: Heparin sodium + Benzocaine

Domestic Nigepan suppositories are available only by prescription, but are also an analogue of Hepatrombin G, since they are used as an anticoagulant, local anesthetic and anti-inflammatory agent for hemorrhoids.

Proctosan

Manufacturer: STADA, Germany
Release form: ointment and rectal suppositories

Active ingredient: Bufexamac + Bismuth subgallate + Lidocaine hydrochloride

Proctosan suppositories have an astringent, wound-healing, drying, local anti-inflammatory and anesthetic, as well as antihemorrhoidal effect.

This analogue of Gepatrombin G is used not only for hemorrhoids, but also for fissures, ulcers of the anus and rectum to relieve inflammation and itching.