What temperature should be lowered and is ibuprofen harmful for coronavirus? Talked to a therapist

What is Ibuklin

The drug contains two active ingredients: ibuprofen and paracetamol. These are effective non-steroidal compounds with analgesic properties. Together they have a more complete therapeutic effect:

• Ibuprofen, with its moderate analgesic properties, more significantly reduces the intensity of inflammation;
• Paracetamol is a good analgesic and relieves painful symptoms for a long time.

Both substances affect thermoregulation centers and normalize body temperature during fever and acute infectious processes.

Ibuklin is produced:

• for adults: in the form of oblong capsules with a film shell: orange. In 1 piece contains 400 mg of ibuprofen and 325 mg of paracetamol;
• for children: Ibuprofen Junior with a measuring spoon in the package: non-coated soluble tablets, pink, with small inclusions, have a mint smell, ibuprofen content - 100 mg, paracetamol - 125 mg.

Additional components of the drug include: talc, silicon, starch, magnesium stearate.

Ibuklin

Ibuklin (ibuprofen + paracetamol) is a combination drug containing the NSAID paracetamol and the non-narcotic analgesic ibuprofen. The pharmacological “bundle” of paracetamol + ibuprofen is perhaps a “classic” for eliminating fever and pain syndromes. Both of these drugs are successfully used individually, but their fixed combination - Ibuklin - is of much greater interest to doctors. Clinical studies have shown its high effectiveness in relieving fever (with acute respiratory infections and similar conditions) and pain (degenerative-dystrophic diseases of the spine and joints, intercostal neuralgia, lumbodynia, etc.) syndromes. At the same time, the effectiveness of paracetamol and ibuprofen in combination is significantly higher than each drug separately: both fever and pain are eliminated much faster, and this more pronounced effect develops already on the first day of pharmacotherapy after 1-2 doses of the drug. Ibuklin has a relatively small number of side effects, which do not exceed those associated with monotherapy using any one of these drugs. The most “vulnerable” place for Ibuklin is the upper parts of the digestive tract, where the drug can manifest itself as heartburn and discomfort in the epigastric region. This fact dictates the need to take measures to protect the gastrointestinal tract, including histamine H2 receptor blockers or proton pump inhibitors in the drug course. The patient should be informed about the danger of drug abuse and the need to strictly adhere to the recommended duration of the medication course, which should not exceed 3-5 days. It should be noted that during clinical trials of Ibuklin, side effects requiring early discontinuation of the drug were not recorded. Both paracetamol and ibuprofen belong to safety class 4 drugs.

Their combination, even when exceeding the recommended dose twice, does not increase toxicity to the kidneys and liver, because Ibuklin contains each of these drugs in a reduced dose, which protects against the risk of overdose. The duration of action of the drug is four times longer than each of its components separately. It should be borne in mind that the doses and concentration ratios of the active ingredients in children's and adults' Ibuklin are significantly different, so it is not possible to obtain a child's dose by simply dividing the tablet in half. Non-steroidal anti-inflammatory drugs and, in particular, Ibuklin, become a real lifesaver for the practicing physician, allowing them to solve problems across a wide therapeutic range. If you adhere to the recommended doses and dosage regimens, then problems are practically eliminated. Ibuprofen acts as an analgesic and has an anti-inflammatory and antipyretic effect. By suppressing cyclooxygenase-1 and 2 (COX 1 and 2), it suppresses the chain of metabolic transformations of arachidonic acid, reducing the concentration of inflammatory mediators and pain reactions of prostaglandins both in the inflammatory focus itself and in tissues not affected by pathological processes. Paracetamol is a non-selective COX blocker, acting mainly in the central nervous system. It has virtually no effect on the mucous membrane of the digestive tract and electrolyte metabolism. Ibuklin relieves joint pain during movement and rest, increases mobility, and eliminates morning stiffness. When taking the drug, it is necessary to avoid the simultaneous use of other NSAIDs or combination drugs containing NSAIDs or paracetamol. When using Ibuklin for more than 5 days, it is necessary to monitor the liver profile and blood picture.

Mechanism of action of Ibuklin

The active substances of NSAIDs inhibit the production of prostaglandins - pain mediators, and at the same time facilitate the proliferative and esudative period of inflammation. Ibuklin eliminates pain syndromes of various origins, reducing the severity of accompanying symptoms:

• reduces stiffness of limbs due to arthritis;
• eliminates malaise and fever during ARVI.

The drug is completely absorbed from the stomach into the bloodstream, the concentration reaches a maximum within 2 hours. Penetrates into biological fluids, including articular synovium. The effect of Ibuklin begins 15–20 minutes after administration and lasts up to 5–6 hours.

The drug has no effect on the duration and intensity of the disease, having only a symptomatic effect.

What temperature should be lowered and is ibuprofen harmful for coronavirus? Talked to a therapist

Why is it important to drink a lot of fluids at high temperatures and why give up heavy foods, as well as what “antipyretic” folk remedies can be dangerous to health, said general practitioner Olga Sergeevna Shukh.

– Why might the temperature rise?

– We must remember that body temperature changes throughout the day. So, in the morning a person’s temperature may be lower than usual – even 35.5–36.0 degrees Celsius, and in the evening it may rise slightly by about half a degree. This is an absolutely normal physiological process. If the temperature has risen above 37.0 degrees, then this is a reason to pay attention to your health and understand the reasons for the increased indicators.

Elevated body temperature is a protective reaction of our body to any external “stimulant”. These can be infectious agents: viruses/bacteria and foreign substances that are formed during many inflammatory, allergic processes or during the breakdown of tumor tissues. Physical factors, such as injury or overheating, can also cause an increase in body temperature.

This allows our immune system to activate and fight the disease. Therefore, there is no need to try to knock down the indicators on the thermometer. We always focus on our well-being.

– When should you sound the alarm and go to the doctor?

– If your body temperature exceeds 38.5 degrees Celsius and is accompanied by severe chills and fever, lasts more than 5 days, and there are other symptoms of an acute respiratory infection, you should consult a doctor if at least one of these signs is present.

– What temperature should be lowered?

– Doctors recommend starting to reduce body temperature when the temperature reaches 38.5 degrees. However, this indicator is conditional. It was installed so that a person without medical education could navigate. It's better to monitor your well-being. If, for example, the body temperature has reached 38.0 degrees, but the person feels extremely unwell, then it is necessary to take measures regardless of the values ​​​​on the thermometer. And, conversely, a fever can reach 39.0 degrees, but a person tolerates this condition relatively well, then it is not advisable to reduce this temperature with medications.

In children, it is always necessary to reduce body temperature above 38.5 degrees. At higher values, febrile seizures are possible in young children.

– How can you lower your temperature yourself at home?

– To effectively combat body temperature, the following conditions are necessary. Firstly, the room should have cool air, approximately 18–22 degrees, humidity 40–60%. Frequent airing of the room and wet cleaning are necessary.

Secondly, you need to take a shower with cool water. Sweaty and dirty skin cannot fully remove excess heat. An alternative is wiping with water at room temperature. You need to make sure that your clothes are dry and clean.

Thirdly, a prerequisite is to drink plenty of fluids. This can be drinking water, fruit drinks, warm teas, natural juices, fresh juices. At high temperatures, metabolic processes accelerate, oxygen consumption increases, fluid loss increases, and an increased load on the heart is created, which can be dangerous for chronic patients and children. No medicine will work if you are dehydrated. Food must be easily digestible, so that the body spends energy on fighting the disease, and not on digesting “heavy” food. If you don't want to eat, you don't need to force yourself.

Fourthly, you need to take medications according to the instructions or as prescribed by your doctor.

– When should you call an ambulance?

– An ambulance should be called for a fever above 38.5, which not only does not decrease with medications and other methods, but is also steadily increasing.

For example, you have a high temperature - 38.5 degrees and feel extremely unwell, you took ibuprofen at a dosage of 200 mg. Wait an hour (it is during this period of time that the tablet forms of the drug begin to act). If after a while the temperature does not decrease, but rather increases, then a more effective method is needed (for example, increasing the dosage of the drug or taking another drug).

If the temperature rises, and the measures taken and the medications taken do not help, then it’s time to call an ambulance. A medic will be able to assess the situation. Perhaps this is a viral disease with the development of pneumonia, which causes such a temperature.

However, during a pandemic, you need to understand that ambulances are contact persons for COVID-19 and the risk may outweigh the benefit. Only as a last resort, I recommend calling an ambulance to reduce high body temperature. Therefore, if possible, it is better to go to a clinic or call a doctor at home if it is during the daytime.

– A couple of months ago on social networks they talked about the dangers of ibuprofen and paracetamol, are they really so harmful?

– The side effects of ibuprofen and paracetamol have been known for a long time, but at the same time they effectively help fight fever. In general, any medicine can turn out to be poison if the dosage is violated.

The dosage should be chosen by the doctor depending on the state of health and medical history.

Ibuprofen and paracetamol are safe if taken as directed. If you have a fever, you can take these medications at four-hour intervals. I do not recommend using ibuclin, which contains two substances at once: ibuprofen and paracetamol. In this case, not only does the effectiveness of temperature reduction increase, but the risk of side effects also increases. Including hepatotoxicity (negative effects on liver cells).

You can also get by with paracetamol and ibuprofen separately, alternating these drugs. In some cases, you can additionally take an antispasmodic for spasms of the peripheral vessels of the extremities, when your hands and feet are “icy”.

I would like to draw your attention to the fact that pharmacies have a huge assortment of antipyretic drugs, they all have trade names; you must always pay attention to the active substance so as not to take the same drug in a high dosage.

– And as for the famous “troika”, can it be used in critical cases?

– “Troichatka” consists of three active components: analgin, drotaverine and diphenhydramine. Analgin anesthetizes and reduces temperature, drotaverine is an antispasmodic and acts on smooth muscle cells, dilates peripheral vessels during spasm, diphenhydramine, a first-generation antiallergic drug, has a sedative effect (it makes you want to sleep). These medicinal devices make up the injection that is given by the ambulance crew.

Troychatka can be taken in tablet form. The only thing is that the effect does not develop as quickly as from an injection. After this, the person falls asleep and wakes up feeling well and with a lower temperature. Do not forget that this is only eliminating symptoms, and not treating the cause of increased or high body temperature!

– What should not be done to reduce the temperature?

– You cannot create the so-called “greenhouse effect”: cover with several blankets, dress warmly. This contributes to dehydration of the body.

Do not wipe the sick person with alcohol or vinegar. This can be harmful and cause an allergic reaction or skin burn.

– What other mistakes exist when reducing high temperatures?

– Some people think that by drinking alcohol they will immediately gain weight. On the contrary, because of this, the body begins to experience enormous stress. Moreover, alcohol is not compatible with any of the medications, especially anti-inflammatory ones.

Daria ZIMAK

Photos from open Internet sources

Indications

Ibuklin is used independently, as well as in complex treatment, to eliminate negative symptoms:

• for colds, respiratory infections, flu;
• myalgic attacks and neuralgia;
• acute and chronic pathology of the musculoskeletal system;
• dental problems;
• bruises, sprains and other physical injuries;
• postoperative syndrome;
• algomenorrhea;
• migraines.

Description of the drug

Today Ibuklin is used for various pains: dental, headache, muscle, menstrual. The drug is effective for the following problems:

• colds, accompanied by body aches and migraines;
• exacerbation of chronic pathologies of tissues and joints;
• in the first days after injury;
• toothache;
• period;
• inflammation of the reproductive organs.

The indications are identical for adults and children (the only difference is the dosage).

How to take Ibuklin

The pills are swallowed with water half an hour before meals or 2 hours after. There is no need to chew or grind them. General dosage recommendation:

• 1 capsule three times a day;
• the interval between doses is at least 4 hours;
• You are allowed to take up to 6 capsules per day;
• For people with liver disease, it is important to take a break of 8 hours, taking no more than 3 doses of the drug per day.

The maximum duration of treatment is up to 5 days. If symptoms do not subside, you should consult your doctor to prescribe another drug.

IBUCLIN®

INSTRUCTIONS for use of the medicinal product for medical use IBUCLIN®

Registration number: P N011252/01
Trade name of the drug: Ibuklin®

INN or generic name of the drug: Ibuprofen + Paracetamol

Dosage form: film-coated tablets

Composition Each film-coated tablet contains: Active ingredients: ibuprofen 400 mg and paracetamol 325 mg. Excipients: microcrystalline cellulose 120 mg, corn starch 76 mg, glycerol 3 mg, sodium carboxymethyl starch (type A) 7 mg, colloidal silicon dioxide 5 mg, talc 8 mg, magnesium stearate 6 mg. Shell: hypromellose 6 pps 11.32 mg, sunset yellow dye (E110), aluminum varnish 1.78 mg, macrogol-6000 2.2 mg, talc 4.06 mg, titanium dioxide 0.16 mg, polysorbate-80 0, 16 mg, sorbic acid 0.16 mg, dimethicone 0.16 mg.

Description Capsule-shaped, orange-coated tablets with a score line on one side; For individual tablets, marbling of color is allowed.

Pharmacotherapeutic group: combined analgesic drug (NSAID + analgesic non-narcotic drug).

ATX code: M01AE51

Pharmacological properties

Pharmacodynamics A combined drug whose effect is determined by its constituent components. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that has analgesic, anti-inflammatory, and antipyretic effects. By inhibiting cycloxygenase (COX) 1 and 2, it disrupts the metabolism of arachidonic acid, reduces the amount of prostaglandins (mediators of pain, inflammation and hyperthermic reaction), both in the site of inflammation and in healthy tissues, suppresses the exudative and proliferative phases of inflammation. Paracetamol - indiscriminately blocks COX, mainly in the central nervous system, has little effect on water-salt metabolism and the mucous membrane of the gastrointestinal tract (GIT). Has an analgesic and antipyretic effect. In inflamed tissues, peroxidases neutralize the effect of paracetamol on COX 1 and 2, which explains the low anti-inflammatory effect. The effectiveness of the combination is higher than that of individual components. Relieves arthralgia at rest and during movement, reduces morning stiffness and swelling of joints, and helps increase range of motion.

Pharmacokinetics

Ibuprofen. Absorption is high, quickly and almost completely absorbed from the gastrointestinal tract (GIT). The time to reach maximum concentration (TCmax) after oral administration is about 1-2 hours. Communication with blood plasma proteins is more than 90%. The half-life (T1/2) is about 2 hours. It slowly penetrates into the joint cavity, accumulates in the synovial fluid, creating higher concentrations in it than in the blood plasma. After absorption, about 60% of the pharmacologically inactive R-form is slowly transformed into the active S-form. Metabolized. More than 90% is excreted by the kidneys (no more than 1% unchanged) and, to a lesser extent, with bile in the form of metabolites and their conjugates.

Paracetamol. Absorption is high, binding to plasma proteins is less than 10% and increases slightly with overdose. Sulfate and glucuronide metabolites do not bind to plasma proteins even at relatively high concentrations. The Cmax value is 5-20 μg/ml, TCmax is 0.5-2 hours. Distributed fairly evenly in body fluids. Penetrates the blood-brain barrier. About 90-95% of paracetamol is metabolized in the liver to form inactive conjugates with glucuronic acid (60%), taurine (35%) and cysteine ​​(3%), as well as a small amount of hydroxylated and deacetylated metabolites. A small portion of the drug is hydroxylated by microsomal enzymes to form highly active N-acetyl-n-benzoquinone imine, which binds to the sulfhydryl groups of glutathione. When glutathione reserves in the liver are depleted (in case of overdose), the enzyme systems of hepatocytes can be blocked, leading to the development of their necrosis. T1/2 – 2-3 hours. In patients with liver cirrhosis, T1/2 increases slightly. In elderly patients, drug clearance decreases and T1/2 increases. It is excreted by the kidneys mainly in the form of glucuronide and sulfate conjugates (less than 5% unchanged). Less than 1% of the administered dose of paracetamol passes into breast milk. In children, the ability to form conjugates with glucuronic acid is lower than in adults.

Indications for use

• - symptomatic treatment of infectious and inflammatory diseases (colds, flu), accompanied by fever, chills, headache, muscle and joint pain, sore throat;
• - myalgia;
• - neuralgia;
• - back pain;
• — joint pain, pain syndrome in inflammatory and degenerative diseases of the musculoskeletal system;
• - pain from bruises, sprains, dislocations, fractures;
• — post-traumatic and postoperative pain syndrome;
• - toothache;
• - algodismenorrhea (painful menstruation).

The drug is intended for symptomatic therapy, reducing pain and inflammation at the time of use, and does not affect the progression of the disease.

Contraindications for use: Increased individual sensitivity to the components of the drug (including other NSAIDs), peptic ulcer of the stomach and duodenum in the acute phase, gastrointestinal bleeding, severe renal failure (creatinine clearance (CC) less than 30 ml/min), complete or an incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs (including a history), damage to the optic nerve, genetic absence of glucose-6-phosphate dehydrogenase, diseases of the blood system, the period after coronary artery bypass surgery; progressive kidney disease, severe liver failure or active liver disease, confirmed hyperkalemia, active gastrointestinal bleeding, inflammatory bowel disease, pregnancy (III trimester), children under 12 years of age.

Use during pregnancy and lactation In the first and second trimesters of pregnancy, use is possible only as prescribed by a doctor in cases where the potential benefit outweighs the possible risk to the mother and the potential risk to the fetus. The use of the drug in the third trimester of pregnancy is contraindicated. If it is necessary to use the drug during lactation (breastfeeding), breastfeeding should be stopped. Experimental studies have not established the embryotoxic, teratogenic and mutagenic effects of the components of the drug Ibuklin ®.

Method of administration and dosage regimen: Orally (before or 2-3 hours after meals), without chewing, with a sufficient amount of water. For adults. 1 tablet 3 times a day. The maximum daily dose is 3 tablets. Children over 12 years old (body weight more than 40 kg). 1 tablet 2 times a day. The duration of treatment is no more than 3 days as an antipyretic and no more than 5 days as an analgesic. Continuation of treatment with the drug is possible only after consultation with a doctor.

Precautions for use: Coronary heart disease, chronic heart failure, cerebrovascular diseases, dyslipidemia/hyperlipidemia, diabetes mellitus, peripheral arterial disease, smoking, creatinine clearance less than 60 ml/min, history of ulcerative lesions of the gastrointestinal tract, presence of Helicobacter pylori infection, elderly age, long-term use of NSAIDs, alcoholism, severe somatic diseases, simultaneous use of oral glucocorticosteroids (including prednisolone), anticoagulants (including warfarin), antiplatelet agents (including acetylsalicylic acid, clopidogrel), selective serotonin reuptake inhibitors (including citalopram, fluoxetine, paroxetine, sertraline). Viral hepatitis, liver and/or kidney failure of moderate and mild severity, benign hyperbilirubinemia (Gilbert, Dubin-Johnson and Rotor syndrome), liver cirrhosis with portal hypertension, nephrotic syndrome.

Symptoms of overdose, measures to assist in case of overdose Symptoms: gastrointestinal disorders (diarrhea, nausea, vomiting, anorexia, epigastric pain), increased prothrombin time, bleeding after 12-48 hours, lethargy, drowsiness, depression, headache, tinnitus, impaired consciousness, heart rhythm disturbances, decreased blood pressure, manifestations of hepato- and nephrotoxicity, convulsions, possible development of hepatonecrosis. If you suspect an overdose, you should immediately seek medical help. Treatment: gastric lavage during the first 4 hours; alkaline drinking, forced diuresis; activated carbon orally, administration of SH-group donors and precursors for the synthesis of glutathione-methionine 8-9 hours after an overdose and N-acetylcysteine ​​orally or intravenously after 12 hours, antacid drugs; hemodialysis; symptomatic therapy. The need for additional therapeutic measures (further administration of methionine, intravenous administration of N-acetylcysteine) is determined depending on the concentration of paracetamol in the blood, as well as the time elapsed after its administration.

Possible side effects From the gastrointestinal tract (GIT): NSAID gastropathy - nausea, vomiting, heartburn, anorexia, discomfort or pain in the epigastrium, diarrhea, flatulence; rarely – erosive and ulcerative lesions, bleeding; liver dysfunction, hepatitis, pancreatitis; irritation or dryness in the mouth, pain in the mouth, ulceration of the gum mucosa, aphthous stomatitis; constipation. From the nervous system and sensory organs: headache, dizziness, insomnia, anxiety, nervousness, irritability, agitation, drowsiness, depression, confusion, hallucinations; rarely – aseptic meningitis (more often in patients with autoimmune diseases); hearing loss, tinnitus, blurred vision, toxic damage to the optic nerve, blurred vision or double vision, scotoma, amblyopia. From the cardiovascular system: heart failure, increased blood pressure, tachycardia. From the hematopoietic organs: anemia (including hemolytic and aplastic), thrombocytopenia, thrombocytopenic purpura, agranulocytosis, leukopenia. From the respiratory system: shortness of breath, bronchospasm. From the urinary system: allergic nephritis, acute renal failure, nephrotic syndrome, edema, polyuria, cystitis. Allergic reactions: skin rash, itching, urticaria, Quincke's edema, bronchospasm, dyspnea, allergic rhinitis, dry and irritated eyes, swelling of the conjunctiva and eyelids, eosinophilia, fever, anaphylactic shock, erythema multiforme exudative (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome). Laboratory indicators: decrease in serum glucose concentration, decrease in hematocrit and hemoglobin, increase in bleeding time, increase in serum creatinine concentration, increase in the activity of “liver” transaminases. Other: increased sweating. With long-term use in high doses: ulceration of the mucous membrane of the gastrointestinal tract, bleeding (gastrointestinal, gingival, uterine, hemorrhoidal), visual impairment (impaired color vision, scotoma, amblyopia).

Interaction with other drugs and (or) food products When using the drug Ibuklin ® simultaneously with drugs, various interaction effects may develop. When taken simultaneously with acetylsalicylic acid, ibuprofen reduces its anti-inflammatory and antiaggregation effect (an increase in the incidence of acute coronary insufficiency in patients receiving small doses of acetylsalicylic acid as an antiaggregation agent is possible after the start of administration). Combination with ethanol, glucocorticosteroids, corticotropin increases the risk of erosive and ulcerative lesions of the gastrointestinal tract. Ibuprofen enhances the effect of direct (heparin) and indirect (coumarin and indanedione derivatives) anticoagulants, thrombolytic agents (alteplase, anistreplase, streptokinase, urokinase), antiplatelet agents, colchicine - the risk of developing hemorrhagic complications increases. Enhances the hypoglycemic effect of insulin and oral hypoglycemic drugs. Weakens the effects of antihypertensive drugs and diuretics (by inhibiting the synthesis of renal prostaglandins). Increases the blood concentration of digoxin, lithium and methotrexate. Caffeine enhances the analgesic effect of ibuprofen. Cyclosporine and gold preparations increase nephrotoxicity. Cefamandole, cefoperazone, cefotetan, valproic acid, plicamycin increase the incidence of hypoprothrombinemia. Antacids and cholestyramine reduce the absorption of the drug. Myelotoxic drugs contribute to the manifestation of hematotoxicity of the drug.

Special instructions Avoid simultaneous use of the drug with other drugs containing paracetamol and/or non-steroidal anti-inflammatory drugs. When using the drug for more than 5-7 days as prescribed by a doctor, peripheral blood counts and the functional state of the liver should be monitored. With the simultaneous use of indirect anticoagulants, it is necessary to monitor the indicators of the blood coagulation system. Co-administration of Ibuklin ® with other NSAIDs should be avoided. To avoid possible damaging effects on the liver, you should not drink alcohol while taking the drug. The drug may distort the results of laboratory tests when quantitatively determining glucose, uric acid in blood serum, and 17-ketosteroids (the drug must be discontinued 48 hours before the test).

Impact on the ability to drive vehicles and machinery During the treatment period, the patient should refrain from engaging in potentially hazardous activities that require increased attention and speed of psychomotor reactions.

Release form: Film-coated tablets, 400 mg + 325 mg. 10 tablets in a PVC/Al blister. 1, 2 or 20 blisters are packed in a cardboard pack with instructions for use.

Storage conditions: In a dry place, protected from light and out of reach of children, at a temperature not exceeding 25 °C.

Shelf life: 5 years. Do not use after the expiration date stated on the packaging.

Conditions for dispensing from pharmacies Without a prescription.

Manufacturer Dr. Reddy's Laboratories Ltd. Hyderabad, Andhra Pradesh, India.

Manufacturing address Dr. Reddy's Laboratories Ltd. Plot No. 137, 138 and 146, Sri Venkateswara Cooperative Industrial Complex, Bollaram, Jinnaram Mandal, Medak District, Andhra Pradesh, India.

Send consumer complaints to the following address: Representative office of Dr. Reddy's Laboratories Ltd.: 115035, Moscow, Ovchinnikovskaya embankment, 20, building 1 Tel, 783-29-01 Fax

Ibuklin for children

Patients under 12 years of age are prescribed children's Ibuklin:

• children weighing up to 15 kg: no more than 3 tablets per day;
• with a body weight of 16–21 kg: 1 tablet up to 4 times during the day;
• with a weight from 22 to 40 kg: no more than 6 pcs. per day.

For convenience, the tablets can be diluted in a spoon of water before taking.

Adolescents 12 years of age and older are allowed the drug in an adult dosage: 1 capsule 2-3 times a day.

The recommended treatment period is 3 days, maximum 5 days.

Instructions for use

The drug is intended for internal use before meals or 2-3 hours after meals. The tablet should be swallowed whole and washed down with enough water.

An adult can take up to 3 tablets per day with an interval of at least 4 hours. For older people and for those who have problems with the functioning of the kidneys and liver, the interval is 8 hours.

Children who have reached 12 years of age and who weigh more than 40 kg can take 2 tablets per day.

If the tablets are used to reduce the temperature, then they can be taken for no longer than 3 days, for pain relief - up to 5 days. If you need to extend the course of treatment, you should consult a specialist in advance. Otherwise, adverse reactions may occur.

After taking Ibuklin, its high concentration in the blood is immediately achieved. Over time it gradually decreases. If you do not follow the interval, the concentration will reach a minimum value. Therefore, to achieve maximum results, you should follow the instructions.

Side effects

Among the possible negative reactions of the body while taking Ibuklin:

• epigastric pain, nausea, dry mouth;
• dizziness, development of anxiety;
• blood pressure surges, tachycardia;
• changes in laboratory blood parameters;
• swelling;
• increased sweating.

If severe symptoms develop, the possibility of individual intolerance to the drug should be excluded and the dosage should be reconsidered.

Composition and release form

Ibuklin contains the following substances:

• active ingredients: ibuprofen and paracetamol;
• auxiliary elements: corn starch, glycerol, magnesium stearate, etc.

The active substances together allow you to achieve maximum effect. Additional components are responsible for the rapid absorption of the drug and transport of necessary elements into the circulatory system.

The composition of the drug allows it to be classified as a combination drug.

The drug is available only in tablet form.

Contraindications

You should stop using the drug:

• in case of an allergic reaction to its components;
• with internal bleeding;
• for ulcerative processes of the stomach and intestines;
• severe renal, liver failure;
• inflammation of the optic nerve;
• bronchial asthma;
• polypous growths in the sinuses
• pathologies of the hematopoietic system;
• pregnant women in the last trimester.

The toxicity of Ibuklin increases when taken simultaneously with aspirin, anticoagulants, cyclosporine and gold.

What problems does it help with?

Tablets are prescribed for pathological conditions in which inflammatory processes, pain, and increased body temperature occur. These conditions include:

• fever accompanied by fever and infections (including colds);
• muscle pain;
• pain in the area of ​​peripheral nerves as a result of non-infectious lesions;
• back pain caused by problems with the spine;
• tooth pain;
• joint pain due to the appearance of inflammatory reactions;
• painful menstruation.

Ibuklin is prescribed for symptomatic treatment, for inflammatory processes and elevated body temperature as part of general therapy. It does not affect the course of the disease and does not slow down its development.