Postinor: principle of action after unprotected intercourse


Recommended for use within 72 hours after sexual intercourse in the absence or inadequate use of other means of protection against pregnancy. They suppress ovulation and prevent unwanted fertilization. The contraceptive effect of Postinor is more effective the less time has passed since the unprotected act. Find out where you can urgently consult with a gynecologist about the possibility and advisability of taking Postinor and how much the clinic’s service costs in emergency situations.

Operating principle

Levonorgestrel prevents conception, having a progestogenic and antiestrogenic effect on the body. Preventing the onset and maintenance of pregnancy is manifested in two methods:

  • First, the ovulatory process is suppressed, which prevents the release of the egg of ovulation and pregnancy;
  • If ovulation has occurred and the egg could be released from the ovary, levonorgestrel prevents implantation of the developing fertilized egg. Rejection of the endometrium occurs, which is manifested by the onset of bleeding, similar to menstruation.

Price for Postinor

Advice from a gynecologist on the use of postinor and the cost of clinic services in an emergency

Medical servicesprice, rub.
Doctor's consultation, advice on prevention2 500
Insertion of the IUD within 120 hours “after”5 000
Zhenale tablet (including doctor's consultation)3 500
Ginepristone (including doctor's appointment)3 500
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Make an urgent appointment with a gynecologist
Find out more on the topic:
GenaleGynepristone

How to use

Postinor must be taken orally. If unprotected sexual intercourse occurs no later than 72 hours later, then 2 tablets of the drug are taken. Initially, one tablet is taken, and after 12 hours the second tablet is taken.

The second tablet must be taken no later than 16 hours later, as the effect of the initial dose will not be maintained.

If vomiting occurs within 3 hours after taking any of the tablets, you must take an additional tablet.

Before the onset of the next menstruation, it is necessary to use a barrier method of contraception. Repeated use of Postinor during one menstrual cycle is prohibited due to the risk of side effects. If your period has not begun and there is concern that pregnancy has occurred, you should consult a doctor for an examination and an ultrasound.

Postinor is considered a means of “fire” contraception, so it should be taken as rarely as possible and not used as a contraceptive. If taken frequently, complications arise - menstrual irregularities, bleeding and lack of menstruation - amenorrhea

Contraindications and side effects of Postinor

The product is contraindicated:

  • Girls under 16 years old.
  • Persons who have hypersensitivity to levonorgestrel or other components included in the composition.
  • During the beginning of pregnancy, including the intended one.
  • With a tendency to thrombosis.
  • For lactase deficiency and lactose intolerance.

If a woman is prone to ectopic pregnancy or has suffered from inflammatory diseases of the fallopian tubes in the past, then Postinor is also not recommended.

When taking the pills, breastfeeding can be continued after at least 8 hours. The most possible side effects are:

  • Nausea, vomiting.
  • Increased fatigue.
  • Dizziness and headache.
  • Pain in the lower abdomen.
  • Non-menstrual bleeding.
  • Delay of menstruation for 7 days and their irregularity.
  • Swelling of the mammary glands.

The occurrence of undesirable effects is caused by the influence of the drug on the hormonal background of a woman. Not all side effects of Postinor may occur. The cycle may not fail.

The drug is prescribed with caution for diseases of the liver and biliary tract, and a tendency to vein thrombosis.

If signs of an ectopic pregnancy appear, such as pain in the lower abdomen, dizziness and increased heart rate, it is necessary to call an ambulance and be hospitalized in a hospital.

Conclusion

The drug Postinor is a postcoital contraceptive taken within 72 hours after sexual intercourse. The product is a “firefighter” contraceptive drug, not suitable for continuous use. To make sure that Postinor has worked, you need to wait for the onset of the menstrual cycle, and if there are no menstrual days, undergo an ultrasound to make sure there is no pregnancy.

MAKE AN APPOINTMENT

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Abortion and contraception clinic in St. Petersburg - department of the medical gynecological association "Diana"

Make an appointment, tests or ultrasound via the contact form or by calling +8 (812) 62-962-77. We work seven days a week from 09:00 to 21:00.

We are located in the Krasnogvardeisky district, next to the Novocherkasskaya, Ploshchad Alexander Nevsky and Ladozhskaya metro stations.

The cost of a medical abortion in our clinic is 3,300 rubles. The price includes all pills, an examination by a gynecologist and an ultrasound to determine the timing of pregnancy.

INSTRUCTIONS

on the use of Postinor® tablets - how to drink, when and how much.

Manufacturer: Gedeon Richter, Hungary. Gedeon Richter Plc. Gyömrői ut 19-21. H-1103 Budapest Hungary / JSC "Gedeon Richter", 1103 Budapest, st. Dymroyi 19-21, Hungary

Compound:

Active ingredient: Levonorgestrel, 750 mcg tablets: 2 pcs. Excipients: colloidal silicon dioxide, potato starch, magnesium stearate, talc, corn starch, lactose monohydrate.

Description

Tablets are white or almost white, disc-shaped, chamfered, with a circular engraving “INOR” on one side. Efficiency - up to 95% (subject to the instructions for use and timing of administration). The trade name is “Postinor”, ​​the analogue is “Escapelle”.

Postinor is a synthetic gestagen with a contraceptive effect, pronounced gestagenic and antiestrogenic properties. With the recommended dosing regimen, levonorgestrel suppresses ovulation and fertilization if sexual intercourse occurs on “dangerous days”, when the possibility of conceiving a child is greatest. It can also cause changes in the endometrium that prevent implantation of an already fertilized egg. Increases the viscosity of cervical mucus, which interferes with the advancement of sperm. Postinor for abortion is not effective if implantation of the fertilized egg into the uterine wall has already occurred - for these purposes there are special means for medical abortion in the early stages.

Contraceptive Postinor in different countries of the world, photos of packaging

Application of Postinor

With the help of Postinor tablets, pregnancy can be prevented in approximately 85% of cases. The more time passes between sexual intercourse and taking the drug, the lower its effectiveness (95% during the first 24 hours, 85% from 24 to 48 hours and 55% from 48 to 72 hours).

Thus, it is recommended to start using Postinor tablets as soon as possible (but no later than 72 hours) after sexual intercourse, if no protective measures were taken or they were insufficient.

Indications for taking Postinor are:

  1. no contraception was used at all;
  2. the condom broke during sexual intercourse;
  3. the spermicidal tablet did not have time to dissolve;
  4. you made a mistake in calculating the day of ovulation;
  5. missed a dose or did not take COCs for two days in a row;
  6. you have been a victim of sexual violence.

The drug is indicated for use from 16 years of age. Before you start taking it, be sure to read the instructions, ideally get a consultation with a gynecologist. Adolescents and girls under 16 years of age can take Postinor in exceptional cases (including rape); consultation with a specialist is first required to exclude pregnancy and select the likely best alternative.

How to take Postinor

Postinor is taken orally - you need to take 2 tablets in the first three days after an episode of increased risk of unwanted conception. The second tablet should be taken 12 hours (but not later than 16 hours) after taking the first tablet.

To achieve a more reliable effect, Postinor should be taken as soon as possible after unprotected sexual intercourse (no later than 72 hours). If vomiting occurs within 3 hours after taking the 1st or 2nd tablet, you should take another tablet.

Postinor can be used at any time of the menstrual cycle. In case of irregular menstrual cycle, it is necessary to first exclude pregnancy using appropriate methods.

How many times can you take Postinor? After taking emergency contraception, use a local barrier method (eg, a condom) until your next period. Gynecologists do not recommend the use of the drug during repeated unprotected sexual intercourse during the same menstrual cycle due to an increased risk of uterine bleeding, menstrual irregularities and other adverse reactions.

It is unacceptable to use Postinor as a means of permanent contraception, as this reduces its effectiveness and increases the risk of increased adverse effects. As a last resort, it is allowed to take tablets no more than twice within one month.

Should I drink Postinor?

Almost since school age, many girls have known about the “magic pill” Postinor, which is not difficult to buy in a pharmacy in Moscow without a prescription. After all, it can help out in a difficult situation, and prices for Postinor in 2022 - 2022 still seem to be relatively affordable, even for teenage girls. Everything would be fine if it weren’t for the presence of a fairly large number of contraindications and possible side effects for this emergency contraception, which cannot be ignored, especially at a young age.

Postinor or Escapelle?

It is impossible to say which of these two drugs is better, because... in fact, these are the same medicine, because They contain the hormone levonorgestrel. There is only one difference - the composition of 1 tablet of Escapel contains 1.50 mg of active ingredient levonorgestrel, while the Postinor package contains 2 tablets (see photo) of 0.75 mg each. each.

Contraindications
  1. hypersensitivity to the components of the drug;
  2. severe liver failure;
  3. age up to 16 years;
  4. established or suspected pregnancy;
  5. rare hereditary diseases such as lactose intolerance.
  6. diseases of the liver and biliary tract, jaundice, Crohn's disease,
  7. period of active lactation.

Postinor is contraindicated for use during pregnancy. If pregnancy occurs while using an emergency method of contraception, then based on the available data, no adverse effect of the drug on the fetus has been identified. Levonorgestrel passes into breast milk. The potential effect of the drug on the child can be practically eliminated if the mother takes both tablets immediately after the next feeding, and after taking them, refrains from feeding for 24 hours.

Side effects

  • Allergic reactions: sometimes urticaria, rash, itching, swelling of the face.
  • Very often - pain in the lower abdomen, acyclic spotting (bleeding); often - soreness of the mammary glands, delayed menstruation (no more than 5-7 days, if longer - it is indicated to exclude pregnancy).
  • Often - nausea; often - vomiting, diarrhea.
  • Periodically dizziness, headache.
  • Very often - fatigue, weakness, mood changes.

The appearance of pain in the lower abdomen, in the middle, on the right or left, weakness, dizziness, increased heart rate, and fainting may indicate an ectopic (ectopic) pregnancy and requires immediate contact with a gynecological hospital to clarify the diagnosis. A woman’s history of ectopic pregnancy, tubal surgery, or pelvic inflammatory disease and adhesions may speak in favor of an ectopic pregnancy.

After taking Postinor®, menstruation usually proceeds normally and occurs on time. Sometimes menstruation may start a few days earlier or later. Women should be advised to visit a gynecologist to select and begin using one of the methods of regular contraception.

I took Postinor and became pregnant - what to do?

Does Postinor help against pregnancy? In the vast majority of cases, yes, it helps, achieving an effectiveness of 95-98% if the timing and time of taking the tablets is observed according to the instructions for use. However, the effectiveness of this drug may be affected by various factors and, unfortunately, the drug may not work or protect against unwanted conception.

How to understand that Postinor did not help? First of all, pay attention to possible early signs of pregnancy, which usually every girl can feel quite soon. Most often it is the following:

  • menstruation after Postinor did not come on time and there is a delay of more than 3-5 days;
  • after taking it, bleeding began 2-3 days later, continued for up to 7 days and stopped, but there was no menstruation at the scheduled time;
  • taking Postinor caused vomiting after 20-30 minutes, and there is a possibility of a decrease in the effect;
  • probable symptoms of conception appeared (nausea, fluid retention, taste and olfactory signals, pain in the lower abdomen, etc.);
  • libido has changed, appetite has increased or, conversely, decreased;
  • Pharmacy tests show questionable or weakly positive results.

Find out how to determine pregnancy or delay after taking Postinor?

The drug Postinor is not intended for abortion. Taking this drug 72 hours after PA does not save you from unwanted pregnancy, in addition, it causes severe harm to the body. Trying to terminate a pregnancy by drinking a large dose of levonorgestrel is pointless and very harmful - this will not lead to the desired effect, and all hormone-dependent target organs of the female body (ovaries, uterus, mammary glands, etc.) will be dealt a powerful blow with unpredictable consequences.

If postinor did not help and pregnancy occurred, but this is not currently part of your plans, there are civilized methods of early abortion, and there are good specialists and private clinics in Moscow where you can solve this problem with minimal losses!

Analogues of Postinor

If for some reason you cannot drink Postinor, existing analogues (in terms of active substance content or effect) can easily replace it. All drugs - analogues of Postinor are recommended only for emergency (postcoital) contraception (after unprotected sexual intercourse or the unreliability of the method of protection used)!

The active ingredient in all these drugs is the same - levonorgestrel, which suppresses ovulation and fertilization if sexual intercourse occurs in the preovulation phase, when the possibility of fertilization is greatest. They may also cause changes in the endometrium that prevent implantation. Attention!!! The drugs are ineffective if implantation has already occurred.

Analogues of Postinor according to the active substance:

• Microlute; • Levonorgestrel; • Escapelle; • Eskinor-F.

Drugs similar in effect to Postinor:

• Zhenale • Ginepristone • Mifepristone-72 (discontinued).

What's better than Postinor?

Safe analogues of Postinor, safe and less harmful in their effects on the body, are zhenale and gynepristone. The price category for these contraceptive drugs is approximately the same, but the side effects are incomparably different. Below is a comparative table that analyzes the significant properties of these two pharmaceuticals.

Postinor or Zhenale - compare which is better, safer and less harmful

Tablets and their propertiesGenalePostinor
Terms of useup to 3 days1-2 days
Efficiency✦✦✦✦✦✦✦✦✦✦
Number of receptions12
Blood discharge after✦✦✦✦
Nausea, vomiting✦✦✦
Lower abdominal pain✦✦✦✦
Exacerbation of female diseases✦✦
Skin rash, itching✦✦
Delay of menstruation✦✦✦✦
Off-cycle daub✦✦✦✦
Effect on the fetus✦✦✦✦
The need to have an abortion if it doesn’t help✦✦✦
Effect of weight on efficiency✦✦
Don't breastfeedup to 2 weeks24 hours
Side effects when taken again✦✦✦✦✦
Recommended by WHO✦✦✦✦✦✦
Reviews from doctors✦✦✦✦✦✦✦

Legend: ✦—minimum, ✦✦✦✦✦—maximum

The safest drug substitutes

Despite the frequent use of Postinor, its generally accepted, safe and most effective analogues are hormonal drugs or an intrauterine device. All of them are recommended by WHO to prevent unwanted pregnancy.

Mirena

This product is an intrauterine device that contains 52 mg of levonorgestrel (this is several times higher than its concentration in Postinor). Additionally, it contains the elastomer polydimethalsilaxane, barium sulfate, and iron oxide. The spiral complex consists of:

  • insertion tubes;
  • piston;
  • flange;
  • housings;
  • slider.


Pros and cons of the drug

The intrauterine contraceptive itself is T-shaped. Its main task is a local gestagenic effect on the uterus. Due to the high concentration of levonorgestrel, the cellular and structural morphology of the endometrium changes, the motor activity of sperm is inhibited, and the cervical mucus thickens. This whole chain leads to the prevention of fertilization.

The active substance begins to flow immediately after installation of the spiral and goes directly to the target organ (uterus and appendages). Mirena must be administered within the first 5-6 days after unprotected sexual intercourse, which guarantees the prevention of pregnancy.

It is prohibited to use it in girls who have not given birth and have not been examined, as well as those who have a large number of sexual partners (the risk of genital tract infection is high).

Also contraindications are:

  • presence of pregnancy;
  • acute inflammatory process of the pelvic organs;
  • cervical dysplasia;
  • malignant neoplasms of the uterus or ovaries;
  • allergy to the components of the spiral.

Installation of the IUD should only be done by an experienced specialist, since the risk of uterine perforation is high.

Escapelle

The basis of the medication is also levonorgestrel in an average therapeutic dosage of 1.5 mg. Produced in Hungary. As an emergency contraceptive, the drug affects ovulation and fertilization. Effective in the first 72 hours after sexual intercourse, during which contraceptive methods were not used. In a later period, it is ineffective, since there is a high probability of implantation of the fertilized egg in the uterine cavity.


Properties of the drug

Accordingly, contraindications are pregnancy, as well as individual intolerance to the drug and liver failure. Escapelle does not replace regular contraception and does not affect menstrual function. After using this medication, local barrier contraceptives (condom, spermicide, cervical cap) must be used throughout the subsequent cycle.

The most common side effects are:

  • nausea or vomiting;
  • headache;
  • bowel disorders;
  • bleeding not associated with menstruation;
  • increased fatigue.

Dwella

It is a representative of the group of hormonal drugs-modulators of the reproductive system, a means of emergency contraception. Produced by the Hungarian pharmaceutical company Gedeon Richter. The tablet contains 30 mg of the active ingredient - unipristal acetate.

Additional substances are: lactose monohydrate, povidone and magnesium stearate. It can be used, unlike Postinor, within 5 days after unprotected sexual intercourse. If vomiting occurs 2 hours after taking the tablet, you should take another one.

Contraindicated in case of pregnancy, allergic reaction to components, lactose intolerance, lactase deficiency, severe liver disease. It is also prohibited for girls under 18 years of age to use.

Dwella is a less harmful analogue of Postinor. Cases of undesirable effects are rare. Manufacturers report the likelihood of vomiting, nausea, and dysmenorrhea. It has a moderate effect on the ability to drive a vehicle, so when taking it you should stop driving.

The cheapest similar products

On the pharmaceutical market there are analogs for emergency contraception that are cheaper than Postinor. The difference in price is due to the active substance used in the drug, its concentration and the manufacturer.

Gynepristone

The drug contains an active substance different from all other drugs - mifepristone. Additionally included:

  • calcium stearate;
  • sodium glycolate;
  • microcellulose.

The drug blocks the action of progesterone at the receptor level, competitively binds to glucocorticosteroids, promotes myometrial contractility, inhibits ovulation, and prevents implantation of a fertilized egg.

Produced by the domestic concern “Obninskaya CFC”, which is located in the Kaluga region. Used for emergency prevention of pregnancy. Contraindicated in the following conditions:

  • allergic reaction to the drug;
  • adrenal insufficiency;
  • disturbances in fibrinolytic activity of the blood;
  • inflammatory diseases of the uterus and appendages;
  • severe extragenital pathology.


Adrenal insufficiency

It is not recommended to use Ginepristone in combination with non-steroidal anti-inflammatory drugs. The effectiveness of the medication is high when used within three days after coitus. There is currently no information about cases of overdose.

Genale

The basis of the drug is mifepristone. Produced in Russia. According to its pharmacological action, the drug is an antiprogestogen. In different dosages it can effectively influence the condition of the female genital area.

For emergency postcoital contraception, 10 mg of the medication should be used within 72 hours after exposure. At a dosage of 50 mg it can inhibit the growth of myomatous nodes in the uterus. Not used as a primary contraceptive.


Zhenale inhibits ovulation and prevents the implantation of a fertilized egg. Has high bioavailability – up to 80%. Prohibited for use at the slightest suspicion of pregnancy, regardless of the topical location.

There is a possibility of profuse bleeding while taking it, so the use of Zhenale is allowed only under the strict supervision of a medical professional. This side effect may require instrumental revision of the uterine cavity (curettage).

The drug is not prescribed in parallel with anti-inflammatory medications. Breastfeeding should be stopped and not resumed for two weeks after taking Zhenale.

Eskinor-F

Contraceptive drug manufactured by Femme Care Ltd. Like Postinor, it contains 0.75 mg levonorgestrel. With the use of Eskinor-F, pregnancy is prevented: the embryo does not attach to the endometrium of the uterus. The medication can also inhibit ovulation.

Effective when used no later than three days after unprotected sexual intercourse. In a therapeutic dose, it does not affect the coagulation properties of blood or metabolic processes.

Given the presence of lactase and its derivatives, Eskinor-F is contraindicated in cases of glucose-galactose malabsorption. Use with caution for diseases of the liver and biliary tract. Later, its use is not able to terminate the pregnancy, since the dose of levonorgestrel contained in the tablet is not enough for this. If the drug is effective, menstrual-like bleeding soon occurs.

Modell 911

The famous Israeli medicine, which is produced by the concern “Lab. Leon Pharma. It contains an increased dose of levonorgestrel - 1.5 mg. This is twice the concentration in Postinor.


According to scientific data, pregnancy was prevented while taking it in 88% of patients. It is quickly absorbed and remains in the circulatory system for a long time (about a day). The active component is excreted exclusively in the form of metabolites.

The drug is effective for three days from the day of coitus, provided that it no longer occurs after that. You can drink it on any day of the menstrual cycle. If, despite all conditions of use, pregnancy does occur, then it is first necessary to exclude ectopic pregnancy.

Modell 911 does not lead to menstrual irregularities. The medicine is not used during pregnancy and breastfeeding.

Which is better: POSTINOR or Zhenale


Contraceptive pills Zhenale.
Photo: stopz.ru The drugs are not analogues of each other. Active ingredient of POSTINOR: Levonorgestrel. Release form: tablets. Active component of Genale: Mifepristone. Produced in the form of tablets for single use (1 tablet per package). The drug POSTINOR is produced in a package of 2 tablets, the second tablet must be taken 12 hours after taking the first (but no later than 16 hours). Both drugs are intended for emergency contraception within 72 hours after unprotected intercourse. Birth control pills POSTINOR can cause ectopic pregnancy, but the drug Zhenale does not. The maximum concentration for Zhenale is achieved after 1.3 hours, for the drug Postinor after 1.6 hours. Both drugs are available with a doctor's prescription!

The country of origin of POSTINOR is Hungary. Zhenale is produced in Russia. Postinor is cheaper in cost than Zhenale. Price per package from 410 rub.

Which is better: POSTINOR or ESCAPELE


POSTINOR and ESCAPE.
Photo: vchemraznica.ru Both drugs are analogues of each other. Active ingredient: Levonorgestrel. Release form: tablets. The difference between the drugs is the number of tablets in the package and, accordingly, the dosage of the active substance. POSTINOR contains 750 mcg of Levonorgestrel, 2 tablets per package. The drug ESCAPEL, dosage 1.5 mg, 1 tablet in a package. Both drugs are available with a doctor's prescription.

The drugs are produced in Hungary. In terms of cost, ESCAPELE is more expensive than POSTINOR. Price per package from 422 rub.

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