Methyluracil suppositories in gynecology and proctology: instructions for use

Methyluracil suppositories containing the active ingredient - methyluracil - are the safest form in the treatment of various gynecological ailments and are often prescribed to patients to provide a regenerating, wound-healing effect.

Suppositories can be used in combination with medications and have earned recognition among many women. Numerous grateful reviews are proof of this.

Description of the drug

The drug, containing the active ingredient dioxomethyltetrahydropyrimidine, is indicated for topical use.

Available in the form of tablets, suppositories, powders and ointments, it has regenerating, anti-inflammatory, anabolic, immunostimulating and wound-healing effects.

Fast:

• restores and normalizes the level of leukocytes in the blood;
• normalizes metabolism;
• accelerates the maturation of epithelial cells;
• nourishes and saturates tissues.

The drug in the form of suppositories is harmless, relieves symptoms of inflammation, has a mild and gentle effect, and does not lead to irritation.

It is suppositories that are more relevant and are often prescribed to patients with hemorrhoids and many gynecological diseases.

How they can be dangerous and in what dose it is better to use them

Methyluracil 10 ointment 25g

The negative effects of the drug have not yet been heard, so the conclusion is obvious - suppositories are well tolerated. Although side effects were observed, they were very rare and in minor manifestations. Among the few symptoms of side effects of the drug are: dizziness, skin reactions in the form of rashes on the skin and itching.

While using suppositories, the patient may feel a slight burning sensation. If similar symptoms are observed, it is better to stop taking the medication and select a medication that has a similar effect on the cause of the disease. The product can be purchased at any pharmacy, as it is available without a prescription. But, despite the fact that there are no restrictions regarding the sale of the drug in pharmacies, it is better to refrain from self-treatment and first undergo an appropriate examination by a doctor.

Properties of suppositories with methyluracil

Creamy white T-shaped suppositories are especially considered effective rectal suppositories or stimulants for the regeneration of vaginal walls and tissues. Recommended for use in many diseases.

Suppositories containing the active substance - methyluracil:

• relieve inflammation;
• stimulate and renew epithelial cells;
• have an anabolic effect;
• heal affected tissue areas;
• increase local immunity;
• activates the production of leukocytes and erythrocytes in the blood;
• synthesize immunoglobulins;
• kill pathogenic microflora in the vagina and anus;
• lead to the complete death of bacteria, namely their protein structures.

Methyluracil suppositories have proven their effectiveness in eliminating gynecological ailments. The active components quickly dissolve upon administration due to optimal body temperature and are absorbed into inflamed tissue areas, having a beneficial effect on the vaginal area.

Methyluracil suppositories, instructions for use

Methyluracil suppositories. Rectal

Suppositories are effective in restoring and renewing cell structure. Thanks to the use of the drug, wound healing is accelerated several times, the protective functions of cells and tissues are increased.

Suppositories have an anti-inflammatory effect. The medicine is a stimulator of leukopoiesis, since it is capable of forming leukocytes and erythrocytes. The form of release of the medicine is suppositories that have a white or cream tint. Medicines such as Metacil, Kolartek, Stizamet, Meturacol can be substitutes. Treatment with the drug is prescribed for the following diseases:

• burns
• fractures
• radiation injuries
• peptic ulcers
• leukopenia
• intoxication
• ulcerative and inflammatory processes developing in the colon.

Suppositories are not only an effective medicine, but also a preventive one. With its use, various injuries and infectious lesions of the genital organs in women are treated. Treatment with this medication has a prescription limitation that applies to patients suffering from certain types of leukemic disease.

The effectiveness of the drug, its rapid action and elimination of the cause of the disease has been proven in the real experience of many patients.

Suppositories are contraindicated for patients with bone marrow diseases, malignant tumors of the gastrointestinal tract, who suffer from intolerance to one of the components of the drug, including methyluracil. To date, there is no data on the use of suppositories by pregnant women and nursing mothers, so during this period it is advisable to refrain from using them or use them only as prescribed by the attending physician.

Operating principle

The suppositories are actively absorbed into the rectal mucosa and within 15-20 minutes from the start of use, the active components are present in the blood plasma. The highest concentration is observed 1.5 hours after penetration.

The drug begins to quickly stimulate and activate cellular protective mechanisms, provide an anti-inflammatory, analgesic and wound-healing effect.

Methyluracil:

• leads to stimulation of many mechanisms in the body;
• restores and regenerates the vaginal mucosa at the cellular level;
• leads to the rapid formation of new cells and the growth of normal tissue, no different from the surrounding layers;
• synthesizes blood cells;
• promotes the formation of a new epithelial layer;
• heals ulcers and cracks;
• reduces pain;
• improves cellular metabolic processes;
• accelerates the restoration of destroyed layers when rough scars have already formed in the vagina;
• boosts the immune system.

The main purpose of methyluracil is to relieve inflammation and eliminate unpleasant symptoms. It is the suppositories that promote rapid healing and resorption of scars and have a destructive effect on proteins secreted by bacteria. Thus, the introduction of pathogenic microflora into the mucous membrane is stopped.

Suppositories are quite applicable in combination with other local drugs and do not affect the weakening (increasing) of their properties. This is important when using drugs with methyluracil by women during pregnancy and lactation.

Indications for use in gynecology

Suppositories are the most common form of prescription by gynecologists for damage to the outer part of the cervix or vaginal mucosa, since they have a gentle effect on tissues and cells, evenly release active substances and are easy to use. It is enough to follow the instructions and observe the dosage.

Candles do not require any special conditions for use and do not lead to adverse reactions.

Can be used in combination with antibiotics and other therapeutic methods. They are acceptable for use during pregnancy because they are not absorbed into the bloodstream and do not have a negative effect on the fetus.

Methyluracil in the suppository:

• heals wounds and stitches well;
• regenerates tissue in the vagina;
• eliminates inflammatory processes;
• restores cellular structures during erosion or after illnesses on the cervix, when small damaged areas of the mucous membrane are observed and infiltrate begins to be released, leading to complications.

Candles are indispensable for use after such harsh techniques as cauterization, electrocoagulation, endocervicosis.

Doctors often prescribe drugs for external use after gynecological operations, for injuries of the vagina and cervix, as well as diseases (vaginitis, cervicitis, vulvitis, cystitis, leukoplakia).

Suppositories are indicated for use by older women at the onset of menopause, when age-related changes are observed and it is simply necessary to increase the elasticity and strengthen the vaginal muscles.

Use for hemorrhoids

Rectal methyluracil suppositories are often prescribed by proctologists for the treatment of hemorrhoids, fissures in the anus, and various injuries in the sigmoid colon.

Suppositories not only relieve many diseases, but also eliminate constipation and are also useful for the prevention of intestinal disorders.

The medicine helps:

• cell renewal;
• healing of wounds and cracks in the anus;
• restoration of damaged mucosa;
• eliminating unpleasant signs.

Suppositories for hemorrhoids are suitable for use during pregnancy and will not lead to a negative effect on the fetus; it is enough to carefully insert into the anus to a depth of the index finger.

To avoid spreading, candles can be stored or kept in the refrigerator before use.

Before starting a treatment course, you need to:

• empty your bowels and go to the toilet;
• wash the anus using hygienic soap;
• lightly wipe the anus with a soft towel;
• take a position lying on your side, bending your knees for easy insertion;
• wait 0.5 hours for better absorption of active substances.

It is advisable to use candles at night. If it is necessary to carry out procedures in the morning, it is not recommended to get out of bed immediately. It’s better to lie down for a while and wait until the candle is completely absorbed.

Mode of application

It is important to follow the regimens and doses prescribed by the doctor, and also follow the instructions without neglecting the instructions. You can administer up to 4 suppositories per day and no more than 2 in 1 session.

Rectal suppositories are indicated for vaginal administration in the treatment of gynecological diseases. Before use:

• carry out hygiene procedures, douche with the addition of a weak solution of potassium permanganate or iodine;
• then carefully insert the suppository into the vagina, lie down for 15-20 minutes in a relaxed state;
• Allow the suppositories to distribute evenly throughout the vaginal cavity and gradually melt.

The treatment course can vary from 10 to 60 days, so it is better to first consult a doctor before use.

Attention! For virgin girls, suppositories are used exclusively rectally.

Features of use during pregnancy and breastfeeding

Many women with the onset of pregnancy experience trouble with itching and burning in the anus, when hemorrhoids or, for example, cervical erosion are diagnosed.

You should not experiment on yourself using methyluracil suppositories during pregnancy or breastfeeding without instructions.

Even such gentle drugs as suppositories with methyluracil can cause serious harm instead of benefit and expose the fetus to risks.

Although pregnancy and breastfeeding are not considered contraindications for the use of methyluracil, and are often prescribed to women if it is necessary to treat gynecological diseases such as colpitis, cervical erosion, vaginal dysbiosis, vaginitis, vulvitis, without waiting for childbirth or the end of the lactation period.

Of course, it is not recommended to use suppositories yourself at home without a doctor’s recommendation.

Instructions for use

It is important to understand that almost all gynecological diseases lead to damage and inflammation of tissue in the vagina, the accumulation of bacteria and microbes, in particular their decay products.

The body experiences stress and begins to react inadequately to such processes. Pathogenic flora begins to accumulate in the vaginal mucosa and ooze out in the form of serous discharge.

In order to increase the effectiveness of the treatment course, before using methyluracil suppositories, it is advisable to treat the vaginal cavity by moistening cotton swabs with antiseptics and gently wiping away mucous accumulations.

If the candles are stored in the refrigerator, you must first rub them in your hands so that they are at room temperature. Next, wash your hands with soap to avoid further infection. Remove the suppositories from the packaging, insert them as deeply as possible into the vagina, holding with 2 fingers and leading from the back wall of the vagina.

If suppositories are used rectally, it is first recommended to give a cleansing enema, then cover the vagina with gauze or a pad so as not to stain the underwear.

The main thing is to act according to the instructions and properly clean the tissue surface of the vagina from any secretions to quickly achieve the effect. After which you need to remain in a lying position for 0.5 hours. The number of procedures performed and the duration of the treatment course are selected by the doctor on an individual basis.

On a note! It is not advisable to use methyluracil suppositories during menstruation and you should refrain from carrying out the procedures and choose another time for treatment. It is also recommended to avoid intimacy so as not to further disturb the damaged vaginal mucosa.

Suppositories can be used in combination with other medications. If unpleasant signs appear after using methyluracil, it is better to consult a doctor. Replacement with other analogues is possible.

Rectal suppositories Nizhpharm Methyluracil - reviews

Margarita
https://med-otzyv.ru/lekarstva/155-m/91528-metiluracil#scomment-381525

My gynecologist prescribed methyluracil suppositories during pregnancy; I was very afraid of harming the baby, but nothing bad happened. Methyluracil suppositories are very effective for the treatment of inflammation in the vagina; they are allowed to be used both during pregnancy and during breastfeeding.

IseCherry

https://irecommend.ru/content/borba-s-takoi-nepriyatnost-kak-gemoroi

After giving birth, the question of how to overcome hemorrhoids became very acute. Not a very pleasant topic, however, I think every second person has encountered it. So, after giving birth, I also faced this problem, which rectal suppositories I used (on the advice of friends) and sea buckthorn and others, but only these Nizhpharm Methyluracil rectal suppositories helped. Literally 3-4 days and I no longer felt discomfort, they helped very quickly. It is also good that they do not cause itching or burning. Another plus is that, compared to sea buckthorn, they do not stain laundry. If you are faced with hemorrhoids, I recommend that you immediately use this remedy and forget about this trouble. Health to everyone!

Ekaterina Gog

https://irecommend.ru/content/pochemu-ranshe-o-nikh-molchal-vrach

After a biopsy and cauterization of the cervical erosion, the doctor recommended buying Methyluracil rectal suppositories. They turned out to be very budget-friendly, the cost of packaging was 70 rubles. The instructions say that these suppositories promote rapid healing, which is exactly what you need. I used it according to the instructions and could not understand how they could help in gynecology. I read information on the Internet and found out that after cauterization, girls used these suppositories vaginally and the erosion healed faster. I went to the doctor for an appointment and asked. She said that Methyluracil suppositories can be placed both rectally and vaginally. It will still have a good effect. I put 10 candles on at night, there was a slight burning sensation. But a month later I saw a doctor and she said that everything had healed well. I am very pleased; before, very expensive suppositories were prescribed for healing and there was no effect.

Maria

https://www.imho24.ru/recommendation/17699/#review21699

Advantages:

low price, effective

Flaws:

didn't find it

Review:

After I became a mother, I was faced with a very unpleasant problem - hemorrhoids. There was severe pain. I used various ointments to treat this ailment. They helped, but not for a long period of time. They were very expensive, but I didn’t notice much of an effect. The pain was relieved, but the hemorrhoids did not stop bleeding. A pharmacist friend advised me to try these suppositories. They are aimed at healing cracks and wounds, which is what I needed. They cost inexpensively 55 rubles, there were 10 pieces in a package. I got rid of this disease in 10 days. I only used two packages, since I used the candles twice a day. The candles have no odor and are convenient to use. The problem has gone away for now and I hope it doesn't come back.

Alenka))))

https://flap.rf/Medicine/Methyluracil (suppositories)/Reviews/7412345

These suppositories were prescribed to my husband when he went to the doctor with a problem such as pain and blood from the intestines.

As it turned out, the cause of this whole problem is hemorrhoids - and this is where such problems come from.

Methyluracil suppositories

- have two indications: pain relief and treatment of inflammatory processes.

Moreover, despite their price, they begin to act almost from the first use, but still the ideal treatment option is a 10-day course of administering these suppositories.

Irina Alekseeva

https://flap.rf/Medicine/Methyluracil (suppositories)/Reviews/6048268

Candles helped me out twice in rather delicate situations. For the first time, a gynecologist prescribed suppositories to me. After treating cervical erosion, the gynecologist advised the use of this drug to speed up wound healing. Healing was surprisingly fast, despite the large area of ​​damage.

The suppositories also helped me with a fissure in my rectum. Painful sensations decreased immediately after the first use.

I'm mommy

https://otzovik.com/review_2588564.html

Advantages:

the remedy itself

Flaws:

No

After giving birth, anal fissures began to bother me from time to time. Somehow I didn’t pay much attention, but recently the exacerbation recurred again and I decided to go to the pharmacy and buy some healing suppositories. The pharmacist gave me the most versatile rectal suppositories, Methyluracil. She said that they would be the most suitable. They cost 91 rubles, 10 candles. I decided to try using them. I was pleased with the effect the very next day. Candles are easy to use and effective. They act locally and are not dangerous to the body. They increase local immunity, regenerate tissue, heal and have an anti-inflammatory effect. I came across methyluracil vaginal suppositories and was also delighted, so I recommend it!!!

Puppet347

https://otzovik.com/review_6099412.html

Advantages:

Effective immediately! Be sure to buy from Nizhpharm

Flaws:

Ukrainian candles dissolve quickly

About a month after giving birth, problems with stool began. Hemorrhoids were cured thanks to Anestezol suppositories! (Cheap and cheerful) But severe constipation began. What did I not eat? No help came. Going to the toilet was hard labor. After using the vaunted Relief candles (so far we have dealt with hemorrhoids, but with a crack it was hell!!!) I wanted to climb the ceiling. Only sea buckthorn suppositories and oak bark baths helped with this pain. But the problem remains. I've never suffered from constipation, so this really surprised me. I decided to look for the problem from the inside. I started taking yogurt in capsules. I bought Lactiale, but was afraid to take it because the instructions said it could cause constipation. And that same evening I used the first Methyluracil suppository. BUT be sure when there is a crack, do not push it in immediately, but hold it in the anus a little so that it melts. The next day I put 4 more candles and went to the toilet in the evening, like a normal white person. But at the same time I drank kefir with bran, soup and tea made from cumin and dill. I have been using candles for 3 days now and have no problems with going to the toilet.

vlada1972

https://irecommend.ru/content/delikatnaya-probelema-kotoraya-sovsem-ne-delikatnaya

I know firsthand what hemorrhoids are. This is a very delicate and very difficult problem, which, unfortunately, torments many girls and women. And if the problem is neglected, the consequences can be much worse. I was treated with different suppositories and ointments, but the effect was the same, short-term.

Until I found out about methyluracil suppositories. They are not expensive, but finding them in the pharmacy turned out to be very difficult. But still, I found them and bought them for 70 rubles. Methyluracil is generally a regenerating drug. And my hemorrhoids were constantly bleeding, so these suppositories were simply necessary for me. So, what kind of candles are these?

The active component of vaginal and rectal suppositories, dioxomethyltetrahydropyrimidine, is a photoprotector and immunostimulant that helps accelerate cellular regeneration, normalize nucleic acid metabolism, normalize the formation of red blood cells and leukocytes, increase the body's resistance to blood loss and oxygen deficiency.

The suppositories are of normal size and you don’t feel any discomfort during insertion. Indications for the use of these suppositories are as follows:

• Erosive and ulcerative colitis;
• Sigmoiditis;
• Proctitis;
• Proctosigmoiditis;
• Exacerbation
  of hemorrhoids;
• The occurrence of anal fissures;
• Colpitis;
• Nonspecific
  vulvitis.

After a week of use, I felt significant relief. And after two weeks I was completely healed of my illness. This is how methyluracil suppositories helped me with my delicate problem. I recommend that you don’t procrastinate with this problem, but get it treated in a timely manner...

TatyD

https://irecommend.ru/content/deshevoe-sredstvo-dlya-resheniya-delikatnoi-problemy

Good day, I want to share my opinion about methyluracil suppositories.

In fact, I decided to resort to this remedy more out of despair, since absolutely nothing helped, relief suppositories are ordinary dummies that do not cure, but for the most part give a short-term effect, I am allergic to sea buckthorn suppositories, proctosedyl suppositories such an awkward shape that in order not to further injure the anus, I did not dare to use them

My mother recommended these candles to me. She said that back in 1988, after giving birth, she was treated with these suppositories and applied cold; nothing more could be done for a nursing mother. Well, I doubted it for a long time, but I still went to the pharmacy and bought candles.

The shape of the candles, which I was very pleased with, is classic; they are inserted easily and painlessly; in order not to injure the wound at all, I ground off the uneven edge of the candle with my fingernail. The candle does not leak, I did not experience any burning or discomfort with them.

The result did not appear immediately, after about a week. I began to notice that I no longer experienced severe pain when pushing and (forgive the details) when passing gas. There was much less blood in the stool. I used to flood the entire toilet, it was so scary that I thought I would die from loss of blood. (This is a ridiculous death, dying in a push)

I used these candles for a month, inserted them according to the instructions, it took a lot of them, several packs. By the way, there are even cheaper methyluracil suppositories, I somehow came across them in a pharmacy, they cost around 70 rubles, they’re just from a different manufacturer, but the effect is the same.

your happiness

https://irecommend.ru/content/khotite-vylechit-gemorroi-podrobnaya-istoriya-moego-lecheniya-vse-kak-doktor-propisal

Not the most pleasant review for me (DO NOT READ FOR THE WEAK NERVOUS) but I think it will be useful to someone, because I didn’t know what to do when this happened...

I would never have thought that I would hear someone say to me “you have primary hemorrhoids”!

Backstory: it all started with a painful and bloody trip to the toilet, I thought it would go away (suddenly there was a wound there, it only hurt to go to the toilet, the rest of the time it didn’t bother me at all, so I doubted it was hemorrhoids). There were no visible changes. I re-read a lot of things, got myself worked up, but decided not to self-medicate. This lasted for the second week, I decided to go to the doctor, because... I just wanted to cry! But not here, that was, in the state hospital there is only a surgeon (with an appointment in a week), i.e. there is no narrow specialist. I went to a paid diagnostic center, overcoming embarrassment, etc., because... Proctologists are only men. But even there it turned out that it was not easy to get to the proctologist, the appointment was only after 5 days.

In general, during the examination, I was dumbfounded by the diagnosis! It’s just not clear where this disease comes from!? My job is partially sedentary, I don’t sit still for more than 20 minutes, I walk a distance of 4,600 km every day, I go to the gym or group classes 3-4 times a week (one might assume that I lifted a lot of weight, but I I don’t overload myself, I don’t work on hardware to the point of fanaticism). The doctor was surprised, after asking me questions about my lifestyle, he wrote out a prescription and recommendations.

The first line in the recipe was methyluracil suppositories. The doctor said that after the first use I would feel the effect (at the appointment I didn’t really believe it), but the next day, going to the toilet was like a normal person! It was such a joy for me, because this illness had already lasted three weeks!!!

The candles themselves must be stored in the refrigerator; they are tightly packed, but easy to open, you just need to pull the top edges of the packaging.

It is necessary to use candles in the morning and evening after going to the shower (and after going to the toilet).

The candles are not large, are inserted painlessly, and do not cause discomfort.

The cost is approximately 70-80 rubles for 10 pieces. There is a cheaper one - the box is shown in the photo.

Warning: candles tend to stain underwear, so don’t forget about panty liners during treatment (I don’t know what men should do). It’s good that I found out about this at home, although the laundry is easy to wash, but what if this had happened at work! Oh God!!!

Treatment is recommended for a period of 1 month. During this time, all symptoms should go away, so you don’t have to go to a second appointment (since I came in on time, the disease was just beginning).

Doctor's recommendation: do not sit still for more than 15 minutes, get up and walk a little.

I definitely recommend this is a quick treatment for hemorrhoids. Be healthy!

Possible side effects

Often, with excessive sensitivity to the components of methyluracil, women experience allergic reactions.

Also, suppositories can lead to short-term symptoms:

• burning;
• itching;
• irritation;
• dryness of the vaginal mucosa;
• hives;
• headache;
• drowsiness;
• dizziness, although the symptoms should not last long and will probably go away quickly on their own. In general, suppositories are well tolerated and side effects are rare.

Methyluracil has a sedative effect, which leads to apathy and fatigue. It is better to stay at home during treatment or wait until the effects of the drug have completely stopped. If such effects occur, it is better to stop use and consult a doctor.

How to take it correctly?

1. Usually the duration of the treatment course is 7-14 days. But only the doctor monitors the treatment process and the degree of recovery; if necessary, he can adjust the regimen, extend the treatment course if necessary, or add other drugs with increasing doses.
2. Methyluracil for gynecological diseases is usually used according to the standard regimen: 1 suppository up to 4 times a day by vaginal or real administration.
3. It is undesirable to use suppositories on your own without consulting a doctor, thereby self-medicating. Although suppositories are sold in pharmacies without a prescription and do not lead to any particular side effects.
4. Before treatment, it is important to first identify the cause of the pathology , as well as the causative agent that caused it. Candles should not be used unless prescribed. To achieve better absorption, the procedures must be carried out in a lying position by inserting the suppository as deeply as possible.
5. When douching, you can use antiseptics: soda, Chlorhexidine or herbal remedies. To avoid staining your laundry, it is advisable to use candles at night and use sanitary pads.

The duration of the training course depends on the severity and neglect of the disease:

• So, when treating erosion or mechanical damage to the mucous membrane of the cervical canal, 1 suppository is used 2 times a day, the treatment course is 2 weeks.
• For vulvitis, the drug is administered vaginally at night. The duration of the treatment course is up to 1 month.
• Girls from 3 to 8 years old can use 1/2 a candle once a day. To make the procedure easier, your fingers can be treated with sterile Vaseline oil.

The dosage directly depends on the disease and age of the patients:

• for adults - 0.5 g 4 times a day
• for children from 3 to 8 years – 25g
• children from 8 to 15 years old - 0.5 g.

The course of treatment is approximately 7 days - 1 month, but extension is possible if necessary, taking into account test results and at the discretion of the attending physician.

Methyluracil 500 mg

Dosage form

Rectal suppositories

Composition for 1 suppository:

Active substance:

Dioxomethyltetrahydropyrimidine (methyluracil) – 0.5 g

Excipients:

solid fat (vitepsol (brands H 15, W 35), supposir (brands NA 15, NAS 50)) - until a suppository weighing 2.3 g is obtained.

Description

Suppositories are white or white with a yellowish or creamy tint, torpedo-shaped. The appearance of a white coating on the surface of the suppository is allowed. In a longitudinal section - homogeneous, without inclusions, the presence of an air rod or funnel-shaped depression is allowed.

Pharmacotherapeutic group

Tissue repair stimulator.

ATX code:

L03AX.

pharmachologic effect

Has anabolic activity. It has hematopoietic, leukopoietic, immunostimulating, anti-inflammatory effects. By normalizing nucleic acid metabolism, it accelerates the processes of cellular regeneration in wounds, accelerating the growth and granulation maturation of tissue and epithelization (including in rapidly proliferating cells of the mucous membrane of the gastrointestinal tract), stimulates erythro- and leukopoiesis, cellular and humoral immunity factors.

Indications for use

Erosive-ulcerative colitis, proctosigmoiditis, anal fissures.

Contraindications

Hypersensitivity to the components of the drug, leukemia (leukemic forms), lymphogranulomatosis, hemoblastosis, malignant bone marrow diseases, children under 8 years of age.

Use during pregnancy and breastfeeding

No special studies have been conducted regarding the safety of using Methyluracil rectal suppositories in pregnant women and during breastfeeding. The drug is used during pregnancy and breastfeeding only if the expected benefit to the mother outweighs the potential risk to the fetus or child.

Directions for use and doses

Rectally: 0.5-1 g 3-4 times a day, children 8-15 years old - 500 mg per day.

The course of treatment is from 7 days to 4 months, depending on the nature of the disease.

Side effect

Allergic reactions and a short-term mild burning sensation are possible.

Overdose

The drug is for rectal use; no cases of drug overdose have been reported.

Interaction with other drugs

There is no information on interactions with other drugs for rectal use; combined use of the drug with other rectal drugs is not recommended.

special instructions

No information available.

Impact on the ability to drive vehicles and machinery

There is no reason to believe that the use of the drug Methyluracil may affect the ability to drive a car or operate machinery.

Release form

Rectal suppositories, 500 mg.

1, 2, 3, 4, 5, 6, 7, 8, 9, 10 suppositories in blister packs made of two-layer PVC-PE or EP-73S film.

1, 2, 3, 4, 5, 6, 7, 8, 9, 10 blister packs together with instructions for medical use of the drug are placed in a pack of boxed cardboard for consumer packaging or chrome-ersatz.

Storage conditions

In a place protected from light, at a temperature not exceeding 25 oC.

Keep out of the reach of children.

Best before date

2 years.

Do not use after the expiration date stated on the label.

Conditions for dispensing from pharmacies

On prescription.

Indication of special precautions when disposing of unused drugs

No information available.

Is it possible to continue treatment during critical days?

Suppositories are so harmless to the female body that even when used on menstrual periods they will not cause much harm. It can be used by women during pregnancy or lactation. But it is important to understand that menstrual flow significantly reduces effectiveness.

The candles do not have time to be absorbed, and most of them flow out. It is unreasonable to expect a positive and quick effect in this case. Still, it is better to start a course of treatment that does not coincide with the arrival of the next menstruation.

If sudden and unexpected discharge occurs, it is reasonable to administer the suppositories rectally. With vaginal administration of suppositories, the effect of methyluracil will be significantly reduced.

You should not plan treatment for critical days. It is better to wait until this period ends or start using the drug rectally.

What can replace candles?

It is reasonable to replace methyluracil suppositories with other analogues, taking into account the composition of the active substances in the drugs, as well as the disease for which it is worth replacing.

Analogs are considered:

• Klion-D containing miconazole and nitrate to eliminate pathogenic microflora in the vagina caused by fungus;
• Viferon in the form of suppositories with the active substance - interferon Alpha, if necessary, provide antiviral, antiproliferative, immunomodulatory effects;
• Immunofan containing tyrosine and arginine to provide detoxification, hepatoprotective, immunomodulatory and antioxidant effects;
• Eucalyminum in composition with eucalyptus to relieve inflammation, eliminate bacterial flora;
• Meturacol in the composition with the active substance - methyluracil to provide wound healing, anti-inflammatory, adsorbent effects;
• Pyrogenal is composed of polysaccharides to provide immunomodulatory, antiallergic and regenerative effects.

Klion Viferon

Imunofan

Pyrogenal

Meturacol
If there are contraindications, the following analogues can be used:

• Ultraproct;
• Anuzol;
• Relief;
• Proctoglivenol;
• candles with sea buckthorn oil;
• preparations containing biologically active additives.

Relief

Ultraproct

Anuzol

Candles with sea buckthorn oil