Capsules, tablets and suspension Sumamed: instructions for use, price, reviews for children and analogues

Compound

The composition of the drug in all forms includes the active component azithromycin dihydrate .
Sumamed tablets also contain the following additional substances: anhydrous calcium hydrogen phosphate, pregelatinized starch, sodium lauryl sulfate, hypromellose, corn starch, magnesium stearate, MCC.

The capsules contain the following additional substances: sodium lauryl sulfate, MCC, magnesium stearate.

The powder from which the suspension is prepared contains the following additional substances: sodium phosphate, sucrose, hyprolose, xanthan gum, flavoring, colloidal silicon dioxide.

Sumamed or Flemoxin solutab - which is better

Manufacturer: Astellas Pharma, Netherlands
Release form: dispersible tablets

Active ingredient: amoxicillin

Synonyms: Amoxicillin, Ospamox, Amosin, Hiconcil

Flemoxin solutab is a penicillin with broad activity. It is a safe and effective alternative to Sumamed. Differences between products in composition and manufacturers. The indications are largely similar, which makes Flemoxin a good substitute if it is not possible to use Sumamed.

Both products are approved for use in pediatric practice. For pregnant and lactating women, it is possible to select optimal dosages, which makes treatment as safe as possible.

Release form

The drug is produced in the following forms:

Tablets 125 mg – biconvex, round, blue, film-coated. There are engravings "PLIVA" and "125". The blister contains 6 tablets.
Tablets 500 mg - biconvex, oval, blue, film-coated. There is a white tablet on the break. There are engravings "PLIVA" and "500". The blister contains 3 tablets.
Gelatin capsules have a blue body and a blue cap; inside the capsule there is a powder or mass that is white or light yellow. The blister contains 6 capsules.
The powder from which the Sumamed suspension is prepared is white or light yellow. It is granular and has a banana or cherry flavor. A homogeneous suspension is prepared from the powder. Contained in 50 ml bottles, the kit includes a measuring spoon or syringe for dosing.

Sumamed or Amoxicillin - which is better?

Manufacturer: Biokhimik, Russia
Release form: tablets, capsules, powder for suspension

Active ingredient: amoxicillin

Synonyms: Amoxiclav, Amosin, Ospamox, Hiconcil, Flemoxin

Amoxicillin is a penicillin, an analogue of Sumamed in action. The medicine is used for children and adults in properly selected doses. The indications for the analogues are very close, which makes such replacements rational and safe. It is possible that some bacteria may develop resistance to Amoxicillin. Before starting treatment, it is important to assess the sensitivity of pathogens to the active substance.

pharmachologic effect

The drug Sumamed is antibiotic , a group of antibiotics - macrolides-azalides . Has a broad spectrum antimicrobial effect. Its mechanism of action is based on the ability to suppress microbial cell protein synthesis. As a result, the growth and reproduction of bacteria slows down. At high concentrations it acts as a bactericidal agent.

Wikipedia indicates that the active component of the drug demonstrates activity against a number of gram-negative and gram-positive anaerobes, as well as intracellular microorganisms, etc.

It should be borne in mind that microorganisms may exhibit resistance to the antibiotic or acquire such resistance over time. Initially, resistance to the drug is observed in gram-positive aerobes Staphylococcus spp., Enterococcus faecalis, in anaerobes - Bacteroides fragilis, in gram-positive bacteria that are resistant to erythromycin.

Pharmacokinetics and pharmacodynamics

As the abstract indicates, the active substance is absorbed quickly into the body, and its distribution also occurs quickly. After taking the drug in a dose of 500 mg, the level of bioavailability is 37%. The highest concentration in the blood is observed after 2-3 hours, it is equal to 0.4 mg/l. Binds to proteins by 7-50%.

Azithromycin is able to penetrate cell membranes, which is why the medicine can be used for infections caused by intracellular pathogens in the body. Phagocytes transport it to the site of infection, and there azithromycin is released.

Can pass through histohematic barriers. There is a 10-50 times higher concentration in cells and tissues compared to blood plasma . In foci of infection, the concentration of the substance is higher than in other tissues.

Demethylated in the liver. The half-life is 35-50 hours. From tissues, the half-life is longer. It is excreted unchanged, approximately 50% through the intestines, another approximately 6% through the kidneys.

Sumamed or Ceftriaxone - which is better?

Manufacturer: Borisov Medical Preparations Plant, Belarus
Release form: powder for the preparation of solution for injection

Active ingredient: ceftriaxone

Synonyms: Azaran, Azarekson, Lendatsin, Medakson

Ceftriaxone is an analogue in action, an antibiotic-cephalosporin. Widely used for bacterial resistance to penicillins and azithromycins. It is used only in the form of intramuscular and intravenous injections. Used when there is no effect from using Sumamed.

Ceftriaxone can be used from birth. Prescription for pregnant and lactating women is allowed. The drug is highly safe.

Indications for use of Sumamed

Indications for the use of this drug are infectious and inflammatory diseases that are caused in the body by microorganisms that are sensitive to this drug:

infections that affect the ENT organs and upper respiratory tract (with sinusitis , sinusitis , tonsillitis , otitis media , etc.);
infections that affect the lower respiratory tract ( bronchitis , chronic bronchitis during exacerbation, pneumonia, etc.);
acne vulgaris (moderate severity);
infectious diseases of soft tissues ( impetigo , erysipelas , etc.);
Lyme disease (early stage disease);
infectious diseases of the genitourinary tract caused by Chlamydia trachomatis.

Sumamed or Suprax - which is better for pneumonia

Manufacturer: Astellas Pharma, Netherlands
Release form: granules for suspension, tablets, capsules

Active ingredient: cefixime

Synonyms: Ixim Lupin, Pancef, Tsemidexor, Cefixime

Suprax is a new generation cephalosporin antibiotic. Differences between analogues in composition, manufacturers and dosage regimens.

Suprax is often used as an alternative when azithromycin is not effective. The medicine is effective for infections of the respiratory tract (bronchitis, pneumonia) and ENT organs. Possible use for mild forms of pathologies of the genitourinary system.

For a child, it is better to use this analogue in the form of a suspension so that the dosage is as accurate as possible.

Contraindications

Contraindications for taking Sumamed are as follows:

increased sensitivity to the components of the drug, as well as to erythromycin or ketolides , antibiotics from the macrolide ;
severe liver or kidney dysfunction;
taking the drug simultaneously with dihydroergotamine and ergotamine.

Children under 12 years of age should also not take 500 mg tablets or capsules. Children under 3 years of age should not take 125 mg tablets. Also, syrup (suspension) should not be given to children under 6 months of age.

With caution, Sumamed for adults is prescribed for myasthenia gravis , impaired liver and kidney function, people who have proarrhythmogenic factors, those undergoing treatment with antiarrhythmic drugs of classes IA and III, patients with severe heart failure, arrhythmia , bradycardia.

Sumamed or Pantsef - which is better?

Manufacturer: Alkaloid, Macedonia
Form: granules for suspension, tablets

Active ingredient: cefixime

Synonyms: Suprax, Ixim Lupine, Tsemidexor

Pancef is a cephalosporin antibiotic that is used orally. Characterized by a wide range of antibacterial effects. Indications for analogues are identical. If bacteria are ineffective or resistant to Sumamed, Pantsef and its analogues are a safe and effective replacement.

This substitute is approved for use by children from 6 months. Nursing and pregnant women can use the medicine only under strict indications and under the supervision of a doctor.

Side effects

The following side effects may occur during administration:

Hematopoietic system: neutropenia , eosinophilia, leukopenia; in very rare cases - hemolytic anemia, thrombocytopenia.
Infectious diseases: candidiasis , pharyngitis , pneumonia, respiratory diseases, gastroenteritis, rhinitis.
Metabolism: anorexia .
Nervous system: paresthesia , irritability , dizziness , drowsiness , headache , taste disturbance, insomnia , etc.
Allergic manifestations: urticaria , hypersensitivity, angioedema .
Visual organs: blurred vision.
Hearing organs: vertigo, hearing loss, tinnitus.
Cardiovascular system: palpitations, low blood pressure , flushing , ventricular tachycardia .
Digestive system: diarrhea , vomiting , nausea , abdominal pain , flatulence , gastritis , constipation , belching , bloating, dysphagia , etc.
Respiratory system: shortness of breath , nosebleeds.
Liver and biliary tract: hepatitis , liver dysfunction , cholestatic jaundice .
Skin and subcutaneous tissues: dry skin, dermatitis , rash, sweating , Stevens-Johnson syndrome , erythema multiforme.
Musculoskeletal system: myalgia, osteoarthritis , back or neck pain, arthralgia.
Reproductive system: testicular dysfunction, metrorrhagia.
Urinary system: dysuria , pain in the kidneys, interstitial nephritis.
Other side effects: malaise, asthenia, fatigue, chest pain, facial swelling , fever .
Changes in a number of laboratory parameters.

Instructions for use of Sumamed (Method and dosage)

The drug should be taken 1 hour before meals or 2 hours after. As a rule, the medicine is taken once a day. There is no need to chew the tablets.

Sumamed tablets, instructions for use

In case of infectious diseases of the respiratory tract and ENT organs, the patient should receive 500 mg once a day for 3 days. In case of infectious diseases of soft tissues and skin, the antibiotic should be taken in the same way.

Patients with erythema migrans are prescribed 1 g of the drug on the first day of treatment, and 500 mg in the next 4 days.

For infectious diseases of the genitourinary tract, a dose of 1 g is prescribed once.

In the case of acne vulgaris, a dose of 500 mg is prescribed once a day, you need to drink it for three days, after which you need to take 500 mg of the drug once a week for 9 weeks.

Instructions for use of Sumamed for children

Children with infectious diseases of the respiratory tract and ENT organs, as well as with diseases of soft tissues and skin, are prescribed a dose of 10 mg per 1 kg of weight once a day for 3 days. So, children weighing 18-30 kg should receive 2 tablets of 125 mg per day (250 mg), children weighing 31-44 kg 3 tablets (375 mg).

Children with tonsillitis or pharyngitis caused by Streptococcus pyogenes are prescribed a dose of 20 mg per 1 kg of body weight per day for three days.

For Lyme disease, a dose is prescribed on the first day at the rate of 20 mg per 1 kg of weight per day, then for four days at a rate of 10 mg per 1 kg of weight once a day.

Suspension Sumamed, instructions for use

Children's syrup (suspension) is indicated for use in children from 6 months to 3 years. To measure the dose for children weighing up to 15 kg, use a syringe; for children weighing more than 15 kg, measure the dose with a measuring spoon.

Children with tonsillitis or pharyngitis caused by Streptococcus pyogenes are prescribed a dose of 20 mg per 1 kg of weight per day, drink for 3 days.

For Lyme disease in the initial stage, a dose of 20 mg per 1 kg of weight per day is prescribed on the first day, then for four days at a rate of 10 mg per 1 kg of weight once a day.

Before use, you should read the instructions on how to prepare the Sumamed suspension. To do this, add 12 ml of water to the powder in the bottle using a syringe. Next, the contents of the bottle should be shaken well. The finished product can be stored for 5 days at a temperature of no more than 25 degrees. Before taking to children, shake the contents of the bottle. The dosage of Sumamed for children is carried out using a spoon or syringe. How to dilute Sumamed 100 mg / 5 ml can be found in the instructions.

Sumamed or Tavanik - which is better?

Manufacturer: Sanofi Aventis, France
Release form: powder for solution for infusion, tablets

Active ingredient: levofloxacin

Synonyms: Levofloxacin, Bactoflox, Levotek, Levoximed, Leflobakt, Lefsan, Remedia

Tavanic is a fluoroquinolone antibiotic based on levofloxacin with a wide spectrum of activity. The analogue is used to treat diseases of the respiratory, genitourinary systems, and soft tissue infections.

The medicine is characterized by high efficiency and high risks of side effects. Not prescribed for children under 18 years of age. Prescription of the product for pregnant and lactating women is prohibited. Patients with kidney disease require dose adjustment.

Interaction

The simultaneous use of antacids does not affect the bioavailability of azithromycin, but its maximum concentration in the blood decreases by 30%.

Simultaneous administration of macrolides with P-glycoprotein substrates leads to an increase in the concentration of P-glycoprotein substrate in the blood.

When azithromycin and Zidovudine , there is a slight effect on the pharmacokinetics of the glucuronide metabolite Zidovudine. Also, with the simultaneous use of these drugs, an increase in the concentration of phosphorylated zidovudine ( metabolite ) in peripheral blood mononuclear cells was observed.

There is a weak effect of azithromycin with isoenzymes of the cytochrome P450 .

Concomitant use with ergot alkaloid , since there is a theoretical possibility of ergotism .

When azithromycin and Atorvastatin , there were no changes in the concentrations of atorvastatin in the blood. But in the post-registration period, there were isolated cases of rhabdomyolysis in people who simultaneously received azithromycin and statins.

The simultaneous use of cimetidine in a single dose does not affect the pharmacokinetics of azithromycin if cimetidine was taken no earlier than 2 hours before azithromycin.

Prothrombin time should be monitored frequently if azithromycin and indirect oral anticoagulants are used concomitantly.

It is recommended to use azithromycin and Cyclosporine very carefully; if such a combination is necessary, the concentration of Cyclosporine in the blood plasma should be monitored and the dose adjusted.

With simultaneous use, the pharmacokinetics of Fluconazole , but the maximum concentration of azithromycin decreased. However, this had no clinical significance, which is why parallel use is allowed.

If azithromycin and Rifabutin , neutropenia is sometimes observed. However, the connection between these phenomena has not been reliably established.

With simultaneous treatment with macrolides and terfenadine, arrhythmia and prolongation of the QT interval may develop, for which Sumamed tablets in this case must be taken with caution.

special instructions

The drug is used with caution for the treatment of people with impaired liver function, both mild and moderate, as there is a possibility of developing severe liver failure and fulminant hepatitis .

Patients who ask doctors whether Sumamed is an antibiotic or not should note that it is an antibacterial drug. Therefore, constant monitoring for the development of superinfections and the presence of non-susceptible microorganisms is required. It is important to adhere to the dosage and duration of treatment indicated in the instructions. Therefore, Sumamed for sore throat in adults and children, as well as the treatment of frontal sinusitis and other diseases, can be practiced only after a doctor’s prescription.

With prolonged treatment, the patient may develop pseudomembranous colitis .

When using macrolides, patients experienced prolongation of cardiac repolarization and the QT interval. As a result, the risk of developing cardiac arrhythmias .

Treatment with Sumamed can lead to myasthenic syndrome or provoke an exacerbation of myasthenia gravis .

The safety and effectiveness of intravenous Sumamed in children and adolescents under 18 years of age has not been established.

People who need to limit their sodium intake should consider the sodium content of the medicine.

You should drive vehicles carefully and perform other actions that require concentration if the patient is undergoing treatment with Sumamed.

Sumamed or Levofloxacin - which is better?

Manufacturer: Teva Pharmaceutical, Israel
Release form: solution for infusion, tablets

Active ingredient: levofloxacin

Synonyms: Baktoflos, Levolet, Levoximed, Levoflox, Leflobakt, Leflox, Maklevo, Remedia, Flexid, Eleflox, Tavanik

Levofloxacin is a fluoroquinolone antibiotic, analogous to a number of antibacterial effects. The drugs' indications and scope of application are largely similar. Differences in composition, mechanisms of action on bacteria.

Levofloxacin is not used in children under 18 years of age. The drug is not allowed to be used by pregnant or lactating women. The likelihood of adverse reactions when taking this analogue is higher than when treating with Sumamed.

Sumamed's analogs

Level 4 ATC code matches:
Ecositrin

Azicine

Rovamycin

AzitRus

Safocid

Clarithromycin

Sumamed Forte

Klarbakt

Azithromycin

Azitro Sandoz

ZI-Factor

Azitral

Azimed

Azicide

Spiramycin-vero

Zitrolide

Ecomed

Macropen

Klacid SR

Klacid

There are both more expensive and cheaper analogues of Sumamed. What can replace the drug is determined only by the attending physician.

The following analogues of this medicine exist:

Azithromycin
Azicine
Azitrox
Zomax
Azax
Zitrox

The price of Sumamed analogues depends on the manufacturer and packaging. For example, the Russian analogue of Sumamed Azithromycin costs several times less. But you should not use a substitute yourself.

Sumamed or Azithromycin - which is better?

Azithromycin is a generic version of Sumamed, therefore, the price of Azithromycin is lower. Many patients are interested in what the difference between the drugs is, besides the cost. Azithromycin, as a copy, does not pass all the studies and tests, unlike Sumamed. Also, the composition of the tablet shells may differ in the preparations.

Sumamed or Suprax - which is better?

Suprax contains another active substance, cefixime . This substance has a pronounced bactericidal effect. But you need to take into account that the highest concentration after administration is achieved 4 hours after administration.

Which is better: Sumamed or Augmentin?

Augmentin contains the active substance amoxicillin , this antibiotic belongs to the group of penicillins. This remedy, unlike Sumamed, can be used from the first days of the baby’s life.

Z-Factor or Sumamed - which is better?

Zi-Factor is an analogue of Sumamed, containing a similar active substance. However, its price is lower.

Sumamed or Azithromycin - which is better and more effective, what is the difference

Manufacturer: Vertex JSC, Russia
Release form: tablets, capsules, powder for preparing a suspension, powder for making an infusion solution

Active ingredient: azithromycin

Synonyms: Sumamed, Hemomycin, Sumatrolide, Zomax, Azitro, Zitrolex, Azitral, Sumamox

The antibiotic Azithromycin is classified as a complete cheap analogue of Sumamed. The spectrum of antibacterial activity of the drugs is the same. Use of the product for children is permitted. In pregnant and lactating women, the medicine is used only under the supervision of a doctor. This substitute practically does not cause serious complications.

Sumamed for children

Children under 12 years of age should not take 500 mg capsules and tablets; children under 3 years of age should not take 125 mg tablets. The syrup should not be taken until the child reaches 6 months of age. Basically, Sumamed suspension is prescribed for children. The dosage for children depends on the child's body weight. Children weighing 18-30 kg should receive antibiotic tablets at a dose of 250 mg per day, children weighing 31-44 kg - 375 mg per day. The dosage of the suspension for children also depends on body weight. Doses should be carefully measured to prevent an overdose in the child. Reviews indicate the effectiveness of the product for bronchitis in children, otitis media in children, etc.

It follows that the prescription should only be made by a pediatrician. Thus, 250 mg capsules can be taken by children only after a clear regimen has been prescribed by a doctor.

Sumamed or Azitrox - which is better?

Manufacturer: Pharmstandard, Russia
Release form: powder for suspension, capsules

Active ingredient: azithromycin

Synonyms: Sumamed, Sumatrolide, Zomax, Azitro, Zitrolex, Sumamox, Azitral

Azitrox is a complete analogue of Sumamed for children in the form of a suspension and capsules for adults. The drugs have identical composition and effects. Treatment regimens are no different. This domestic analogue of Sumamed is widely used to treat complications and bacterial infections.

In pediatrics, the use of a suspension is recommended for precise dosing and to avoid overdose.

Reviews about Sumamed

There are different reviews about Sumamed on the forums. Many patients note that the antibiotic is convenient to take; they also write that it acts quickly for bronchitis, sore throat, and sinusitis. The suspension is also assessed positively by parents, as children like its taste, so it is easy to give to the child.

But there are also reviews that talk about side effects. In particular, when taking Sumamed, diarrhea and pain in the intestines sometimes occur. Parents who use Sumamed for children rarely leave reviews about side effects. They note that the product does not cause allergic reactions. Reviews from doctors are also mostly positive.

Sumamed or Klacid for pneumonia - which is better

Manufacturer: Abbott Lab., UK
Release form: tablets, powder for suspension and infusion solution

Active ingredient: clarithromycin

Synonyms: Clarithromycin, Romiclar

Klacid is a European analogue with a wide spectrum of activity. Like Sumamed, this analogue is classified as a macrolide. Both remedies are similar in effects and indications. Replacing with Klacid is safe and rational.

For pneumonia and bronchitis, the use of Klacid and Sumamed allows you to achieve a quick positive result of therapy with a minimal likelihood of side effects and complications.

For children, this analogue of Sumamed is used from an early age in suspension. During lactation and pregnancy, the product is used with caution.

Sumamed price, where to buy

The price of Sumamed in tablets of 500 mg is from 350 to 450 rubles per pack of 3 pcs. You can buy Sumamed in Moscow at any pharmacy with a doctor's prescription. How much tablets cost in St. Petersburg depends on the place of sale. The cost of 125 mg tablets is from 300 to 400 rubles for 6 pieces. You can buy an antibiotic in 250 mg capsules at a price of 400 to 500 rubles for 6 capsules.

The price of the Sumamed suspension is on average 250 rubles per 50 ml bottle.

Suspension for children in Ukraine (Kyiv, Kharkov, etc.) costs, on average, 200-300 UAH. The powder from which baby syrup is made can be bought at any pharmacy.

Online pharmacies in RussiaRussia
Online pharmacies in UkraineUkraine
Online pharmacies in KazakhstanKazakhstan

ZdravCity

Sumamed powder for suspension.
for internal approx. 100mg/5ml/23ml 17gPliva Hrvatska d.o.o RUB 201 order
Sumamed capsules 250 mg 6 pcs. Pliva
RUB 369 order
Sumamed Forte powder for suspension. for internal approx. 200mg/5ml 35.37gPliva Hrvatska d.o.o
RUR 555 order
Sumamed Forte powder for suspension. for internal approx. 200mg/5ml 16.74gPliva Hrvatska d.o.o
RUB 219 order
Sumamed tablets p.p.o. 125 mg 6 pcs. Pliva Hrvatska d.o.o
RUB 337 order

Pharmacy Dialogue

Sumamed (por. d/p. suspension 100 mg/5 ml 17 g 20 ml) Pliva
180 rub. order
Sumamed forte powder for suspension 200mg/5ml bottle 35.5mlPliva
RUR 536 order
Sumamed (tablet p/o 125 mg No. 6)Pliva
RUB 191 order
Sumamed capsules 250 mg No. 6Pliva
380 rub. order
Sumamed tablets 500 mg No. 3Pliva
409 rub. order

Pharmacy24

Sumamed 1000 mg N3 tablets Pliva Hrvatska d.o.o., Croatia
440 UAH order
Sumamed forte 200 mg/5 ml 1500 mg 37.5 ml suspension
262 UAH. order
Sumamed forte 200 mg/5 ml 600 mg 15 ml suspension Pliva Hrvatska d.o.o., Croatia
183 UAH order
Sumamed forte raspberry 200 mg/5 ml 37.5 ml Pliva Hrvatska d.o.o., Croatia/AT Pharmaceutical plant TEVA, Ugorshchina
259 UAH. order
Sumamed 500 mg N6 tablets Pliva Hrvatska d.o.o., Croatia
440 UAH. order

PaniPharmacy

Sumamed forte liquid Sumamed forte powder 1500 mg for suspension 37.5 ml Croatia, Pliva
208 UAH order
Sumamed capsule Sumamed tablets 250 mg Croatia, Pliva
192 UAH order
Sumamed forte liquid Sumamed forte por. d/p susp. 200mg/5ml 37.5ml Croatia, Pliva
216 UAH order
Sumamed tablets Sumamed tablets 500 mg No. 3 Croatia, Pliva
194 UAH order
Sumamed forte liquid Sumamed forte powder for the preparation of suspension for oral use 200mg/5ml 30ml Croatia, Pliva
210 UAH. order

Sumamed or Augmentin - which is better?

Manufacturer: GlaxoSmithKline, UK
Release form: tablets, powder for suspension

Active ingredient: amoxicillin, clavulanic acid

Synonyms: Amossiklav, Baktoklav, Medoklav, Panklav, Flemoklav

Augmentin is a penicillin analogue with high safety. The breadth of action and indications for use are very similar to Sumamed. Therefore, such products are considered a good replacement.

Augmentin has been proven safe when used in children. As a rule, in childhood a suspension is used for precise dosing.