Diflucan
The drug is available in the form of capsules with different dosages, and there is also a solution for intravenous administration. Diflucan is sold without a prescription (only solution - by prescription). The active substance of the drug is fluconazole. The medicine fights most fungi of the genus Candida and cryptococci. "Diflucan" is used for acute forms of thrush and for episodes of recurring candidiasis. The drug is also prescribed to a partner after the woman has recovered.
To quickly suppress uncomplicated thrush, one tablet is enough. If the process is chronic, the doctor prescribes a course of treatment. Diflucan is easy to use, with almost no side effects, and improvement occurs within a day after taking the medicine.
Diflucan
Pfizer (Pfizer), USA
— cryptococcosis, including cryptococcal meningitis and infections of other localizations (for example, lungs, skin), incl.
in patients with a normal immune response and in patients with AIDS, organ transplant recipients and patients with other forms of immunodeficiency; maintenance therapy to prevent relapses of cryptococcosis in patients with AIDS; - generalized candidiasis, including candidemia, disseminated candidiasis and other forms of invasive candidiasis, such as infections of the peritoneum, endocardium, eyes, respiratory and urinary tract, incl. in patients with malignant tumors who are in the ICU and receiving cytotoxic or immunosuppressive drugs, as well as in patients with other factors predisposing to the development of candidiasis; - candidiasis of the mucous membranes, including the mucous membranes of the oral cavity and pharynx, esophagus, non-invasive bronchopulmonary infections, candiduria, mucocutaneous and chronic atrophic candidiasis of the oral cavity (associated with wearing dentures), incl. in patients with normal and suppressed 183
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Symptoms of thrush
One of the most striking and recognizable symptoms is copious curdled vaginal discharge. They do not always have a characteristic smell. However, thrush may initially present itself differently, before heavy discharge becomes noticeable:
- redness of the mucous membrane of the labia minora, a feeling of sticking together;
- burning sensation spreading to the inner surface of the labia minora during contact with water or during urination;
- itching at the entrance to the vagina;
- peeling, spreading not only to the genital area, but also to the anus.
In men, thrush appears as a white coating and rash that covers the head of the penis. If candidiasis in a man was caused by a malnutrition (poisoning or excessive consumption of sweets), then the disease will manifest itself as itching around the anal ring.
Candidiasis can affect not only the mucous membranes of the genital organs. In infants, thrush often occurs in the mouth when the body experiences a lack of fluid. In adults, oral thrush may appear after taking large doses of antibiotics. It manifests itself as redness of the inner surface of the cheeks, tongue and gums. An astringent sensation is created in the mouth, accompanied by a white coating.
Nystatin
Nystatin was one of the first drugs against fungal infections, and it has proven itself to be excellent. The medicine is available in the form of vaginal suppositories, ointments for external use and tablets. Nystatin is prescribed and the course of treatment determined exclusively by the doctor.
"Nystatin" is prescribed only for acute uncomplicated candidiasis or for prevention. The drug stops the proliferation of the fungus, but is not absorbed into the blood. If prescribed by a doctor, it can be used in pregnant and lactating women, as well as after taking antibiotics. The risk of adverse reactions increases if the course of taking the drug is increased. These are mainly abdominal cramps and nausea.
Nystatin
OJSC Borisov Plant of Medical Preparations (Borimed), Belarus
Polyene antifungal antibiotic, highly active against yeast-like fungi of the genus Candida.
The structure of the antibiotic contains double bonds that are highly tropic to the sterol structures of the fungal cell membrane, which facilitates the incorporation of the drug molecule into the cell membrane and the formation of a large number of channels through which uncontrolled transport of electrolytes occurs; An increase in osmolarity inside the cell leads to its death. Resistance develops very slowly. from 37
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Candidiasis - what is it
Candidiasis is a disease caused by a fungus of the genus Candida. This fungus is present in the vagina of the vast majority of women. In developed countries, Candida spores are recognized as a conditionally pathogenic flora. That is, the presence of traces of this fungus in tests is not an indication for treatment if there are no accompanying symptoms. The female vagina contains countless microorganisms. In each specific case, this is the individual composition of the flora.
When a person’s immunity is not weakened, pathogenic bacteria and fungi only provide balance to the constant environment. But as soon as the immunity weakens or an infectious infection occurs, allowing opportunistic microorganisms to gain numerical superiority over other representatives of the microflora, signs of the disease appear.
Candidiasis occurs in the following cases:
- weakened immunity, for example, as a result of pregnancy;
- the balance of the intestinal and vaginal microflora is disturbed, for example, as a result of poisoning or abuse of sweets, as well as after long-term use of large doses of antibiotics;
- infection occurs after unprotected sexual intercourse with a partner who is a carrier of candidiasis;
Regardless of what caused the thrush, drugs from the group of fungicides are prescribed.
Pimafucin
The drug has such forms of release as vaginal suppositories, cream for topical use and tablets for oral administration. The active substance of Pimafucin is natamycin, which has a powerful antifungal effect. You can buy medicine for thrush without a prescription.
Pimafucin has almost no side effects, it is as safe as possible and is prescribed for acute and chronic forms of candidiasis. As prescribed by a doctor, the drug is approved for pregnant and lactating women.
If thrush is acute, it can be eliminated with local treatment. If it is chronic candidiasis, with relapses, you also need to take a course of Pimafucin tablets. An improvement in the condition is noticeable within a day after starting treatment for thrush, but it is important to complete the course of treatment as prescribed by the doctor. At the same time, you need to treat your partner so that thrush does not recur.
Pimafucin
Astellas Pharma Inc., Japan
A modern drug for the treatment of thrush, available in different dosage forms.
One of the few antifungal agents that can be used without restrictions during pregnancy and breastfeeding. from 228
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Vaginal and thrush medications
Vaginal medications for thrush
Local antifungal agents are used to treat acute or recurrent uncomplicated candidiasis. They act directly on the infection locally in the affected area, i.e. on the skin and vaginal mucosa. The drugs are presented in several dosage forms:
- Vaginal tablets are convenient and their use is not associated with systemic side effects. Intravaginal tablets act locally, preventing the growth of the fungus on the skin and vaginal mucosa.
- Vaginal suppositories are suitable for the treatment of almost all types of VVC, except for severe ones, when a systemic effect is required. It should be noted that suppositories created on the basis of oil components can violate the integrity of latex contraceptives (condoms and diaphragms).
- Creams and ointments are no less common forms of thrush remedies.
Among local antimycotics in Russia, the following active ingredients are most often used:
- ketoconazole;
- natamycin;
- clotrimazole;
- miconazole;
- sertaconazole;
- nystatin;
- fenticonazole;
- econazole
Vaginal antifungal agents for thrush successfully fight the pathogen, however, in order to alleviate the patient’s condition as quickly as possible in the acute phase of the disease, additional anti-inflammatory and healing therapy is necessary. At the same time, to prevent relapses, especially those caused by viral-bacterial associations, drug support of local immunity and antiviral treatment are recommended. Epigen Intim spray has a complex effect in the listed areas thanks to the active component of the drug - glycyrrhizic acid. The unique method of its activation, created by the developers of the drug, significantly enhances the therapeutic effects of the active substance:
- acceleration of regeneration of damaged tissues;
- reduction of inflammation;
- increasing local immunity;
- antiviral effect - fight against viral-fungal associations;
- elimination of itching, burning, dryness.
The drug accumulates in the lesions, while it penetrates into the systemic bloodstream slowly - the drug is found in the blood only in trace amounts. Can be used by pregnant women and during breastfeeding. The spray is equipped with nozzles for intravaginal and external use, which makes its use as convenient as possible.
When the body is weakened or exposed to factors that disrupt the normal microflora of the vagina, local antifungal drugs are prescribed as part of preventive measures. The preventive use of Epigen Intim spray will help strengthen protection against relapses of thrush. Its use is indicated when taking antibiotics, weakening the body after hypothermia, respiratory viral infections, stress, and during travel.
Clotrimazole
This drug is intended for topical treatment of thrush. Presented in the form of solutions, ointments, vaginal tablets. Sold in pharmacies without a prescription.
Clotrimazole is prescribed for acute candidiasis and if the disease recurs. In agreement with the doctor, Clotrimazole is used as part of complex therapy for pregnant and lactating women. The drug has a minimum of side effects, mainly discomfort in the intimate area and increased discharge. Clotrimazole cream is well suited for parallel treatment of a partner. The medicine combines well with antibiotics.
Clotrimazole
Hyperion, Romania
Clotrimazole is an imidazole derivative.
Broad-spectrum antifungal agent. Dermatophytes, yeasts (genus Candida, Torulopsis glabrata, Rhodotorula), molds, as well as the pathogen Pityriasis versicolor (lichen versicolor) and the pathogen erythrasma are sensitive to clotrimazole. from 135
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Pros and cons of using suppositories for thrush
Advantages of topical medications in the treatment of vaginal candidiasis:
- The drug is injected directly into the site of fungal spread, which accelerates the therapeutic effect of treatment with modern means (Zalain, Livarol).
- A number of drugs can be used once, which is very convenient for use;
- Topical agents have reduced absorption, which significantly reduces the incidence of side effects.
Disadvantages of topical drugs:
- There are restrictions on sexual contact during treatment;
- Suppositories contaminate underwear;
- The drugs are ineffective for complex forms of candidiasis; additional oral medications and a repeated course of treatment are required;
- Potent combination drugs have side effects such as vaginal dysbiosis (Terzhinan, Polygynax), additional therapy with suppositories containing lactobacilli is required (Lactobacterin, Vagiflor, Laktonorma, Ecofemin, Acylact).
Klion
"Klion" is available in the form of regular and vaginal tablets. Metronidazole is the active substance of oral tablets, metronidazole + miconazole are contained in vaginal tablets. "Klion" is sold by prescription and is prescribed for both acute and chronic forms of thrush. For better effect, the doctor can combine two forms of the drug. Locally, Klion copes well with complex types of vaginosis. The drug has some special instructions for use - the medicine cannot be used without a doctor’s prescription! At the same time, Klion has a minimum of side effects.
Klion
Efficacy of therapy
The results of treatment procedures are assessed by the absence of pathogenic microflora. The best effect is achieved with the right choice of suppositories for thrush, the component composition of which destroys the fungus that is sensitive to it.
The sensitivity and resistance of the pathogen is determined by bacterial culture of vaginal secretions. Problems with recovery are usually observed with chronic candidiasis - the pathogenic microflora adapts to the drugs, requiring regular replacement of drugs.
Attempts to self-medicate candidiasis often end with the disease becoming chronic, with a permanently disturbed balance of microflora. When using douching, an accelerated progression of pathology is observed, with changes in the vaginal flora towards worsening.
To obtain the expected effect from the fight against candidiasis, a laboratory diagnostic examination and a prescription of a treatment regimen by a doctor are necessary.
