Composition of Panangin
The tablets contain active substances: magnesium aspartate (280 mg) and potassium aspartate (316 mg).
Additional substances: silicon dioxide, corn and potato starch, talc, povidone, magnesium stearate. The shell consists of talc, macrogol 6000, titanium dioxide, methacrylic acid copolymer. The concentrate for Panangin IV solution includes magnesium aspartate (40 mg) and potassium aspartate (45.2 mg), as well as water for injection.
Panangin or Asparkam - which is better for the heart
Asparkam is an analogue of Panangin, but cheaper, with the same active substance. Produced by Belarusian, Russian and Ukrainian pharmaceutical companies. The price of the medicine is 2–5 times lower.
The cheap analogue of Panangin in Russia, Asparkam, is available in tablet and injection form.
According to cardiologists, it is better to take Panangin for several reasons:
- research of the original drug, clinical trials, proven effectiveness;
- the tablet is coated with a protective coating that prevents premature disintegration and provides greater efficiency;
- positive reviews from doctors and patients;
- indications, restrictions on use, adverse reactions and their frequency, interactions with other drugs are written based on clinical trials of Panangin.
Another advantage that makes Panangin more effective than Asparkam is the protection of the tablet from environmental conditions. The medicine is placed in a white jar, which prevents the negative effects of sunlight, moisture, and other factors that destroy the tablets.
The Asparkam tablet is also coated, which in some manufacturers is immediately destroyed when the medicine enters the mouth. The excipients that provide production technology and bioavailability differ.
Asparkam is cheaper than Panangin. However, the cost of the original drug is low - up to 200 rubles, depending on the region. If you have the financial opportunity, it is better to purchase a proven Hungarian drug.
pharmachologic effect
What is the medicine for? It is a source of potassium and magnesium. The drug helps restore electrolyte balance, regulates metabolic reactions and processes, and has a pronounced antiarrhythmic effect.
Potassium takes an active part in synaptic transmission, in the conduction of nerve impulses along fibers, in muscle contractions, and supports the normal functioning of the heart. When potassium metabolism is disturbed, the excitability of muscle tissue and nerves changes. Active ion transport maintains a high potassium gradient across the plasma membrane. Small dosages of potassium contribute to the expansion of the coronary arteries, and in large dosages the microelement narrows their lumen. Potassium has a moderate diuretic effect, negative bathmotropic and chronotropic effects.
Magnesium is a cofactor in three hundred enzyme reactions. Magnesium is an essential element during processes and reactions that provide energy intake and expenditure. Magnesium is part of the pentose phosphate structure of DNA, takes part in the process of cell division and growth, the structure of heredity, and RNA synthesis; is a natural BMCA, prevents the release of free fatty acids and catecholamines during stress, and promotes the penetration of potassium ions into the cell. The drug has a stimulating effect on intercellular phosphate synthesis.
Foreign analogues
Panangin forte
Panangin Forte is produced by the Hungarian company Gedeon Richter and has the same effect as the original drug. Available only in tablet form.
Panangin forte has a more enhanced effect than the original drug
However, the dose of active components in the analog is twice as high as in the original (magnesium - 280 mg, potassium - 316 mg), which leads to its consumption in smaller quantities.
The drug has lower bioavailability and a higher price compared to regular Panangin.
Magnerot
Magnerot is a tableted medicine produced by the German company Mauermann-Artsnaimitel KG.
One tablet contains magnesium ororate dihydrate (500 mg) and additional components. The dose of pure magnesium is 32.8 mg.
The medicine is used in the following cases:
- with a lack of magnesium in the body;
- chronic heart failure;
- arrhythmias;
- myocardial infarction (as part of complex treatment of myocardial infarction or for the prevention of the disease);
- spastic conditions;
- atherosclerosis;
- dyslipidemia;
- gastrointestinal pathologies;
- alcohol abuse;
- pregnancy;
- constant stressful conditions, etc.
The drug has a fairly high price and, unlike Panangin, is contraindicated in childhood.
Pamaton
Pamaton is a Bulgarian drug that is available in the form of film-coated tablets and a solution for injection into a vein.
It has the same properties as its original drug and pursues identical goals.
It has an average but affordable price.
Biolectra Magnesium Fortissimum
Biolectra Magnesium Fortissimum is produced by a German - European leader in the manufacturer of medicines.
The drug contains the daily dose of magnesium necessary for the body (365 mg). Relieves the symptoms of premenstrual symptoms, menopause, pain during menstruation. Helps eliminate feelings of irritability, sleep disturbances, headaches, abdominal cramps, constipation, cramps in the lower extremities, and hangover symptoms. Recommended for people involved in sports, pregnancy, use of certain medications (diuretics, contraceptives), while breastfeeding, while following a diet or poor diet.
It is produced in the form of effervescent tablets with a pleasant lemon and orange taste, at the patient's choice.
The tablets dissolve easily in water and are taken once a day for 2 weeks.
Biolectra Magnesium Fortissimum has a good effect, but does not have a low price.
Foreign pharmaceutical companies have also offered other medicines based on potassium and magnesium, but with almost identical properties:
- Potassium-magnesium aspartate (Germany);
- Potassium and magnesium aspartate Berlin-chemi (Germany).
As a rule, vitamin B6 is also prescribed along with magnesium-based medications, with the help of which the mineral is better absorbed in the body.
The prescription, as well as the replacement of each drug, even if it contains minerals necessary for the body, should be carried out only by the attending physician.
Indications for use of Panangin
Indications for the use of Panangin are as follows; the drug is prescribed:
- for hypomagnesemia , hypokalemia ;
- when taking laxatives and diuretics, glucocorticosteroids;
- for diarrhea, persistent vomiting, taking saluretics;
- for myocardial infarction, heart failure , digitalis intoxication, ventricular extrasystole , atrial extrasystole , supraventricular tachycardia , paroxysmal tachycardia .
Example of a recipe in Latin: Rp.: Dragee “Panangin” N. 20
Panangin or Cardiomagnyl - which is better for the heart
Cardiomagnyl is a drug for thinning the blood and preventing thrombosis, heart attack, thromboembolism and treating unstable angina. The drug contains acetylsalicylic acid and magnesium hydroxide. The latter compound, contrary to common misconceptions, does not compensate for magnesium deficiency in the body to prevent and treat arrhythmia. It envelops the gastric mucosa and prevents destruction and irritation by acetylsalicylic acid.
Cardiomagnyl is prescribed after donating blood for clotting. Panangin does not thicken or thin the blood. It has a different action and mechanism, so it can be used together. Another difference is that Cardiomagnyl is prescribed for lifelong problems, and its substitutes Panangin or Asparkam are prescribed in courses of 14–21 days.
Contraindications for Panangin
The drug is not used for:
- intolerance to fructose, sorbitol ;
- impaired amino acid metabolism;
- chronic pathology of the renal system;
- hemolysis;
- exicosis;
- dehydration;
- arterial hypotension;
- myasthenia gravis;
- atrioventricular block;
- hypermagnesemia;
- hyperkalemia;
- metabolic acidosis;
- Addison's disease.
Panangin is used with caution during pregnancy.
Side effects
Side effects are the following:
- ulceration of the mucous wall of the digestive tract;
- epigastric pain;
- diarrhea;
- bleeding from the digestive system;
- drop in blood pressure;
- bradycardia;
- paradoxical reaction in the form of an increase in the number of extrasystoles;
- dry mouth, nausea, flatulence ;
- hyporeflexia;
- itchy skin;
- dyspnea;
- thrombosis;
- phlebitis;
- paresthesia;
- dizziness;
- increased sweating;
- asthenia;
- myasthenia gravis.
With rapid intravenous infusion, hypermagnesemia and hyperkalemia .
Instructions for use of Panangin (Method and dosage)
Panangin tablets, instructions for use
How to take the medicine? The drug is taken orally three times a day, 2 tablets. Maintenance and preventive therapy: 1 tablet three times a day, course for 3-4 weeks. In some situations, a repetition of the course of therapy is required.
Instructions for intravenous use
Panangin solution is injected intravenously, slowly. The drug is administered at a rate of 20-30 drops per minute, 1-2 times a day, 300 ml. Dosing of the drug Panangin during pregnancy is carried out according to the standard regimen of medication use.
Children can take the medicine from birth.
How to take Panangin for prevention?
If you ask the question of the benefits and harms of Panangin, you should realize that this is a drug that has its own side effects, so you should not use it for prevention. Firstly, in this way you accustom the body to a high content of magnesium and potassium, and secondly, you can provoke an overabundance of these substances, which in turn can cause a lot of negative reactions.
Reviews
Gavrish Boris Leonidovich, general practitioner from the city of Bryansk. The effectiveness of Panangin is, of course, very high. However, its Russian analogue Asparkam has the same effect on the body. Asparkam has a low price, which makes it very popular. Of course, I trust the original remedy more, but the choice remains with the patient.
Svetlana Vasilyevna Babenko, 20 years old, athlete, Perm I have been doing gymnastics since childhood. A year ago, symptoms of arrhythmia began to appear: shortness of breath, dizziness, rapid heartbeat. I couldn’t give up playing sports. The trainer advised me to take medications based on potassium and magnesium. I started taking Aspangin. A few days later I found out that there was a similar, but more popular drug - Panangin. I drank it three times a day, two tablets, for a month. My health returned to normal and I didn’t have to give up my favorite pastime.
Vyachevlav Grigorievich, 43 years old, Saratov region, engineer Over the past six months, my father’s health condition has noticeably deteriorated: he quickly began to get tired, shortness of breath and hand tremors appeared, leg cramps began at night, he constantly wanted to sleep. I was very worried about him. The therapist reported that the body lacks potassium and magnesium. Prescribed Panangin forte. I bought him these pills. After two weeks, dad’s health improved noticeably, and a month later vitality appeared and the unpleasant symptoms disappeared.
Interaction
Panangin is able to enhance the negative bathmotropic, dromotropic effects of antiarrhythmic drugs.
The medication eliminates hypokalemia, which develops against the background of long-term use of diuretics, glucocorticosteroids, and MCS.
NSAIDs, ACE inhibitors, Heparin , potassium-sparing diuretics, Cyclosporine , beta-blockers - increase the risk of developing hyperkalemia.
When using general anesthetics, the inhibitory effect of Panangin on the nervous system increases.
Succinyl chloride, decamethonium, atracuronium, suxamethonium enhance neuromuscular blockade.
The use of enveloping and astringent medications reduces the absorption of potassium and magnesium in the digestive tract.
In combination with insulin , dextrose as part of a polarizing mixture, the heart rate is normalized in case of an overdose of cardiac glycosides, in case of ectopic arrhythmias, myocardial infarction .
Panangin improves the tolerability of cardiac glycosides and is pharmaceutically compatible with their solutions.
Domestic analogues
A large number of analogues of Panangin are produced in the post-Soviet space.
Asparkam is the most popular and cheapest analogue of Panangin. Produced in Russia and Ukraine
Asparkam
The drug is available in the form of tablets and solution. It has almost identical indications to Panangin.
Contains potassium and magnesium (175 mg each) and has no other ingredients, which minimizes the risk of individual intolerance.
Asparkam tablets do not have a shell, which negatively affects the walls of the stomach.
In addition, this Panangin substitute has not been subjected to clinical studies, which makes it impossible to accurately determine its effect on the body.
The positive aspects include the low price of Asparkam and a large number of tablets in the package, which makes it convenient to use.
Asparkam - Farmak produced in Kyiv is available in the form of a solution for administration into a vein. However, its effects are no different from regular Asparkam.
Depending on the manufacturer, Asparkam-L, Asparkam-AKOS, Asparkam-Ros, Asparkam-UBF, Asparkam-Ferein are distinguished.
Aspangin
Aspangin is available in the form of film-coated tablets, as well as a solution for injection and infusion.
Its effect is practically no different from the above drugs and has a low price.
Asmarkad
In principle, there are no differences between Asparkad and Asparkam. The only difference is in the manufacturer. Asparkade is produced in Belarus.
Rhythmocore
Rhythmocor is produced by Ukrainian pharmaceutical companies in the form of capsules and solution for injection.
One capsule of the drug contains 0.3 g of magnesium gluconate and 0.06 g of potassium gluconate. It is a combined agent that has antiarrhythmic, membrane-stabilizing and antioxidant effects.
The drug is recommended in the following cases:
- for arrhythmias of various origins;
- ischemia;
- neurocircular dystonia;
- myocarditis and myocardiopathy;
- liver diseases.
Also, Rhythmocor, as part of a comprehensive treatment, eliminates chronic fatigue.
The drug has good reviews and a reasonable price.
Potassium and magnesium aspartate
Potassium and magnesium aspartate is produced in Ukraine in the form of tablets and solution. Identical to domestic analogues, but has a higher price.
Panangina price, where to buy
The price of Panangin in tablets is about 150 rubles per package No. 50, the price in ampoules is about 160 rubles.
The price of Panangin in Ukraine is 110 and 140 UAH. for tablets and solution, respectively.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Panangin Forte tablets p.p.o.
316mg+280mg 60pcs JSC Gedeon Richter RUB 342 order - Panangin tab. p/o captivity. 158 mg + 140 mg No. 100 JSC "Gedeon Richter-RUS" RU
RUB 285 order
- Panangin tab. p/o captivity. 50 pcs JSC "Gedeon Richter-RUS" RU
RUB 159 order
- Panangin conc. ready solution d/inf 45.2 mg mg/ml + 0.04 g/ml 10 ml 5 pcs CJSC PharmFirma Sotex
155 rub. order
Pharmacy Dialogue
- Panangin (tab.p.pl/rev. No. 50)Gedeon-Richter/Gedeon-Richter-RUS ZAO
172 RUR order
- Panangin forte (tab.pl/vol. 316mg+280mg No. 60)Gedeon-Richter
RUR 358 order
- Panangin (concentrated solution 10ml No. 5) Gedeon-Richter
RUB 163 order
- Panangin (tab.p.pl.vol. 158 mg + 140 mg No. 50) Gedeon-Richter/Gedeon Richter-RUS JSC
162 RUR order
- Panangin (tab.p.pl.vol. 158 mg + 140 mg No. 100) Gedeon-Richter/Gedeon Richter-RUS JSC
RUB 304 order
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Pharmacy24
- Panangin N50 tablets VAT "Gedeon Richter", Ugorshchina
110 UAH. order - Panangin 10 ml No. 5 concentrate for the preparation of solution for infusion VAT "Gedeon Richter", Ugorshchina
142 UAH order
PaniPharmacy
- Panangin solution d/in. 10ml No. 5 Hungary, Gedeon Richter
142 UAH order
- Panangin tablet p/captivity about. No. 50 Hungary, Gedeon Richter
115 UAH order
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