Abdominal aortic aneurysm: treatment, symptoms, causes, prevention · Arterial diseases

What is the aorta

The aorta is the largest vessel in the human body, which carries blood from the heart to the organs and limbs. The upper section of the aorta runs inside the chest, this section is called the thoracic aorta . The lower part is in the abdominal cavity and is called the abdominal aorta . It delivers blood to the lower part of the body. In the lower abdomen, the abdominal aorta divides into two large vessels - the iliac arteries , which carry blood to the lower extremities.
The aortic wall consists of three layers: internal (intima), middle (media), external (adventitia).

Causes

Most aortic aneurysms appear in the part of the aorta that belongs to the abdominal cavity. Although the exact cause of abdominal aortic aneurysms is unknown, many factors may play a role, including:

Smoking tobacco.
Cigarette smoking and other forms of tobacco use increase the risk of aortic aneurysms. In addition to the harmful effects that smoking has directly on the arteries, smoking contributes to the accumulation of lipid plaques in the arteries (atherosclerosis) and high blood pressure. Smoking can also cause rapid growth of the aneurysm and subsequent damage to the aorta.
Hardening of the arteries (atherosclerosis).
Atherosclerosis occurs when lipids and other substances deposit on the inner wall of a blood vessel, increasing the risk of an aneurysm.
Infection of the aorta (vasculitis).
In rare cases, an abdominal aortic aneurysm may be caused by an infection or inflammation that weakens part of the aortic wall.
Aneurysms can develop anywhere along the aorta, but when they form in the upper part of the aorta, they are called thoracic aortic aneurysms. Most often, aneurysms form in the lower part of the aorta and are called abdominal aortic aneurysms.

Abdominal aortic aneurysm

Abdominal aortic aneurysm is a chronic degenerative disease with life-threatening complications. An abdominal aortic aneurysm is defined as an increase in its diameter by more than 50% compared to the norm or a local bulging of its wall. Under the pressure of blood flowing through this vessel, the dilatation or bulging of the aorta may progress. The diameter of a normal aorta in the abdominal region is approximately 2 cm. However, at the site of an aneurysm, the aorta can be dilated to 7 cm or more.

Why is an aortic aneurysm dangerous?

An aortic aneurysm poses a major health risk as it can rupture. A ruptured aneurysm can cause massive internal bleeding, which in turn leads to shock or death.

An abdominal aortic aneurysm can cause other serious health problems. Blood clots (thrombi) often form in the aneurysm sac or parts of the aneurysm tear off, which move with the blood flow along the branches of the aorta to the internal organs and limbs. If one of the blood vessels becomes blocked, it can cause severe pain and lead to organ death or loss of a lower limb. Fortunately, if an aortic aneurysm is diagnosed early, treatment can be timely, safe and effective.

List of sources

Guide to Cardiology / ed. ON THE. Manaka. - Minsk: Belarus, 2003;
Pyrochkin V.M. Dissecting aortic aneurysm. Textbook for 4-6 year students and doctors / V.M. Pyrochkin, E.V. Mironchik. - Grodno, 2004;
Camm A.D., Luscher T.F., Serruis P.V., eds. Diseases of the heart and blood vessels. Guidelines of the European Society of Cardiology. M.: GEO-TAR-Media; 2011;
Sprigins D., Chambers D., Jeffrey E. Emergency therapy: A practical guide: Translated from English. - M.: Geotar Medicine, 2000;
Chazov E.I. Diseases of the heart and blood vessels. In 4 vols. M.: Medicine, 1992. T 3.

Types of aortic aneurysms

There are “true” and “false” aortic aneurysms. A true aneurysm develops due to the gradual weakening of all layers of the aortic wall. A false aneurysm is usually the result of trauma. It is formed from the connective tissue surrounding the aorta. The cavity of the false aneurysm is filled with blood through a crack in the aortic wall. The aortic walls themselves do not participate in the formation of an aneurysm.

Depending on the form there are:

saccular aneurysm - expansion of the aortic cavity on only one side;
spindle-shaped (fusiform) aneurysm - expansion of the aneurysm cavity on all sides;
mixed aneurysm - a combination of saccular and fusiform forms.

Causes and risk factors for the development of abdominal aortic aneurysm

The causes of the development of abdominal aortic aneurysms are very diverse. The most common cause of aneurysm development is atherosclerosis. Atherosclerotic aneurysms account for 96% of the total number of all aneurysms. In addition, the disease can be either congenital (fibromuscular dysplasia, Erdheim's cystic medianecrosis, Marfan syndrome, etc.) or acquired (inflammatory and non-inflammatory). Inflammation of the aorta occurs when various microorganisms invade (syphilis, tuberculosis, salmonellosis, etc.) or as a result of an allergic-inflammatory process (nonspecific aortoarteritis). Non-inflammatory aneurysms most often develop with atherosclerotic lesions of the aorta. Less commonly, they are the result of injury to its wall.

Risk factors for developing an aneurysm

Arterial hypertension;
Smoking;
The presence of aneurysms in other family members. Which indicates the role of hereditary factors in the development of this disease;
Gender: men over 60 years of age (abdominal aortic aneurysms occur less frequently in women).

Symptoms and signs of abdominal aortic aneurysm

In most patients, abdominal aortic aneurysms occur without any symptoms and are an incidental finding during examinations and operations for other reasons.

When signs of an aneurysm develop, the patient experiences one or more of the following symptoms:

A feeling of pulsation in the abdomen, similar to a heartbeat, an unpleasant feeling of heaviness or fullness.
Dull, aching pain in the abdomen, in the navel area, usually on the left.

Indirect signs of abdominal aortic aneurysm are important :

Abdominal syndrome. Manifested by the appearance of belching, vomiting, unstable stool or constipation, lack of appetite and weight loss;
Ischioradic syndrome. Manifested by lower back pain, sensory disturbances and movement disorders in the lower extremities;
Syndrome of chronic ischemia of the lower extremities. Manifests itself in the appearance of pain in the muscles of the lower extremities when walking, sometimes at rest, coldness of the skin of the lower extremities;
Urological syndrome. It manifests itself as pain and heaviness in the lower back, difficulty urinating, and the appearance of blood in the urine.

Harbingers of rupture may be increased abdominal pain.

When an aneurysm ruptures, the patient suddenly feels an increase or appearance of abdominal pain, sometimes “radiating” to the lower back, groin area and perineum, as well as severe weakness and dizziness. These are symptoms of massive internal bleeding. The development of such a situation is life-threatening! The patient needs emergency medical care!

Diagnosis of abdominal aortic aneurysms

Most often, abdominal aortic aneurysms are detected by ultrasound examination of the abdominal organs. Typically, the discovery of an aneurysm is an incidental finding. If a doctor suspects a patient has an aortic aneurysm, modern diagnostic methods are used to clarify the diagnosis.

Methods for diagnosing abdominal aortic aneurysm

Computed tomography in angio mode;
Magnetic resonance imaging in angio mode;
X-ray contrast aorto- and angiography;
Ultrasound duplex or triplex angioscanning of the abdominal aorta.

If necessary, the abdominal and thoracic aorta is examined.

Prognosis and prevention

Unfortunately, abdominal aortic aneurysm is one of the most insidious and unpredictable vascular pathologies, in which the probability of death exceeds 50%. Prevention and timely detection of an aneurysm are essential for a positive outcome. Quitting nicotine addiction, as well as monitoring blood pressure and taking timely measures to normalize it, helps reduce the risk of developing an aneurysm.

Technological progress is helping to reduce the number of diagnostic errors: modern research methods make it possible to identify pathology even in the absence of symptoms. Therefore, people who are at risk - smokers, hypertensive patients, elderly people, as well as those who have a high probability of developing a congenital pathology - should consult a doctor more often for a diagnostic examination. Often, patients are unaware of the development of an aneurysm until it ruptures, but then medical care may not be provided in a timely manner.

Be sure to consult a cardiac surgeon about being examined for the presence of an abdominal aortic aneurysm. Timely detection of the disease can save your life and in any case preserve your health and performance.

Treatment methods for aortic aneurysm

There are several methods for treating aortic aneurysm. It is important to know the advantages and disadvantages of each of these techniques. Approaches to the treatment of abdominal aortic aneurysms:

Monitoring the patient over time

If the aneurysm is less than 4.5 cm in diameter, the patient is recommended to be monitored by a vascular surgeon, since the risk of surgery exceeds the risk of rupture of the aortic aneurysm. Such patients should undergo repeated ultrasound examinations and/or computed tomography at least once every 6 months.

When the aneurysm diameter is more than 5 cm, surgical intervention becomes preferable, since as the size of the aneurysm increases, the risk of aneurysm rupture increases.

If the size of the aneurysm increases by more than 1 cm per year, the risk of rupture increases and surgical treatment also becomes preferable.

Open surgery: aneurysm resection and aortic replacement

Surgical treatment is aimed at preventing life-threatening complications. The risk of surgery is associated with possible complications that include heart attack, stroke, limb loss, acute intestinal ischemia, male sexual dysfunction, embolization, prosthetic infection, and renal failure.

The operation is performed under general anesthesia. The essence of the operation is to remove the aneurysmal expansion and replace it with a synthetic prosthesis. The average mortality rate for open procedures is 3-5%. However, it may be higher if the renal and/or iliac arteries are involved in the aneurysm, as well as due to the patient’s concomitant pathology. Observation in the postoperative period is carried out once a year. Long-term treatment results are good.

Endovascular repair of aortic aneurysm: installation of a stent graft

Endoprosthetics of aortic aneurysm is a modern alternative to open surgery.
The operation is performed under spinal or local anesthesia through small incisions/punctures in the groin areas. Through the above approaches, catheters are inserted into the femoral artery under X-ray control. According to which, in the future, the endoprosthesis will be brought to the aneurysmal extension. An endoprosthesis or stent-graft of the abdominal aorta is a mesh frame made of a special alloy and wrapped in synthetic material. The last stage of the operation is the installation of a stent graft at the site of the aneurysmal expansion of the aorta. Eventually, the aneurysm is “switched off” from the bloodstream and the risk of rupture becomes unlikely. After aortic replacement, the patient is observed in the hospital for 2-4 days and discharged.

This technique allows to reduce the incidence of early complications, shorten the length of patient stay in the hospital and reduce the mortality rate to 1-2%. Observation in the postoperative period is carried out every 4-6 months using ultrasound techniques, CT angiography, X-ray contrast angiography. The endovascular treatment method is certainly less traumatic. About 40,000 such operations are performed annually in the United States alone.

Thus, the choice of treatment method for abdominal aortic aneurysm is based on the individual characteristics of the patient.

Important!

A myocardial infarction suffered 3 months ago - with stable ECG readings, as well as a stroke - in the absence of a pronounced neurological deficit are not a contraindication to surgery.
If there is severe coronary insufficiency, then coronary angiography is performed and the state of coronary blood flow is determined to decide on the priority implementation of coronary revascularization.

Abdominal aortic aneurysm surgery

Abdominal aorta replacement

This is a standard open surgical procedure. In our Center, this operation is performed through a mini-access - an incision on the abdominal wall 5-7 cm long (while in the standard version the incision is 15-20 cm long). After processing the surgical field and preparing a vascular prosthesis of the required length for the time required for the operation, the abdominal aorta is clamped above and below the aneurysm. The aneurysm is excised and a prepared vascular graft is sewn in place of the removed area. After checking the tightness of the seams and installing drains, the wound is sutured.

At the Clinic of High Medical Technologies named after. N.I. Pirogov St. Petersburg State University in the treatment of an aneurysm of the abdominal aorta uses vascular prostheses impregnated with silver, which differ from conventional ones in being particularly resistant to infection. The operations last on average 3-4 hours, after which the patient is transferred to the intensive care unit for observation. In the standard course of the early postoperative period, the next morning the patient is transferred to the ward of the specialized department. The total length of hospitalization for such patients is about 7 days.

It should be noted that there are various forms of the disease that complicate the standard course of treatment, which in some cases may require longer hospitalization.

Aortic endoprosthetics

This method allows you to achieve results comparable to the open surgical technique, only with fewer complications, reducing the length of hospitalization and rehabilitation of the patient by 2 times! The use of this modern method is limited only by some anatomical parameters of the aorta itself and the high cost of the endoprosthesis.