Review of effective ointments for psoriasis: which is the safest


April 27, 2020

Regular treatment with ointment is one of the mandatory methods of treating psoriasis on the arms, legs, face and other parts of the body. The oily texture of such external products allows the active ingredients to remain on the skin for a long time, which makes them more effective than creams and gels.

The list of ointments for psoriasis includes two main types of products:

  • Hormonal. They can bring good results, but have many side effects.
  • Non-hormonal. Less effective, but safer compared to hormonal ones.

Compound

Cynovit shower gel: water, cocamidopropyl betaine, zinc pyrithione, sodium laureth sulfate, acrylic polymer, urea , sodium lauryl-11 carboxylate, glycerin , polyquaternium 7, glyceryl-2 cocoate, climbazole , propylene glycol, disodium EDTA, peppermint oil, methylisothiazolinone, sodium hydroxide , methylchloroisothiazolinone.
Cynovit cream-gel: water, PEG-100 stearate, glyceryl stearate, cetearyl alcohol, isononyl isononanoate, cetearyl glucoside, butylene glycol, isohexadecane, acrylamide/sodium copolymer acryloyldimethyl taurate, polysorbate 80, silica, xanthan gum, methyl methacrylate crosspolymer, pyrroles zinc doncarbonate (zinc PCA), methylchloroisothiazolinone, dipotassium glycyrrhizinate, tocopheryl acetate ( vitamin E ), decylene glycol, retinyl palmitate ( vitamin A ).

Cynovit spray: water, ceteareth-20, cetearyl isononanoate, cetearyl alcohol, glycerin , ceteareth-12, glyceryl stearate, cetyl palmitate, zinc pyrrolidone carbonate (zinc PCA), panthenol , dipotassium glycyrrhizinate, methylisothiazolinone, sodium hydroxide, undecylenamidopropyltrimone ium methyl sulfate, decylene glycol.

Cynovit shampoo: water, cocamidopropyl betaine, sodium laureth sulfate, acrylic polymer, urea , sodium lauryl-11 carboxylate, zinc pyrithione , glyceryl-2 cocoate, polyquaternium 7, propylene glycol, climbazole , panthenol ( vitamin B5 ), cyclopentasiloxane, disodium EDTA, dimethiconol, hydroxide sodium, methylchloroisothiazolinone, peppermint oil, methylisothiazolinone.

Cynovit cream: water, olive oil, glycerin, avocado oil, zinc pyrithione , jojoba oil, shea butter, glyceryl monostearate, cyclopentasiloxane and dimethiconol, stearyl alcohol, ceteareth 6, cetyl alcohol, stearic acid, squalane, palmitic acid, linolenic acid and linoleic triglycerides, carbomer , dipotassium glycyrrhizinate , tocopheryl acetate, methylisothiazolinone, retinol palmitate, decylene glycol, lactic acid , sodium hydroxide, butylated hydroxytoluene.

Pharmacodynamics and pharmacokinetics

Cynovit wash gel and shampoo

zinc pyrithione as one of the active ingredients , which is characterized by anti-inflammatory and antifungal effectiveness, expressed mainly in relation to Pityrosporum orbiculare and Pityrosporum ovale, which are the cause of the inflammatory process and excessive peeling in skin diseases. The antibacterial effect of this component is observed against (Streptococcus spp., Proteus spp., Staphylococcus spp., Pseudomonas aeruginosa and Escherichia coli).

Other active ingredients in shampoo and shower gel are climbazole and urea (urea). Climbazole is an antifungal agent, the effectiveness of which is not inferior to ketoconazole , and urea helps to moisturize the skin and exfoliate dead epithelial particles from it.

Additionally, the shampoo contains panthenol , which exhibits some anti-inflammatory effect and also accelerates epithelization (the formation of fresh tissue in damaged areas).

Cynovit cream-gel and spray

The basis of these cosmetic forms is zinc pyrrolidone carbonate (zinc PCA), which inhibits 5-alpha reductase and reduces the amount of active testosterone found in the sebaceous glands and hair follicles. Zinc PCA reduces the volume of sebum and improves its outflow by reducing viscosity and increasing the elasticity of the walls of the hair follicles. The antibacterial effects of this ingredient are mainly aimed at combating microorganisms : Propionibacterium acnes, Pseudomonas aeruginosa, Staphylococcus epidermalis, Esherichia coli and Staphylococcus aureus.

Other active components - dipotassium glycyrrhizinate (comparable to cortisol in its anti-inflammatory effect), tetranyl-U (characterized by antibacterial and antifungal effectiveness) and panthenol (stimulating skin renewal processes, making it smoother and more elastic) perfectly complement the effects of zinc .

Cynovit cream

The anti-allergenic cream, just like shampoo and gel, contains zinc pyrithione , which reduces the intracellular concentration of ATP and promotes depolarization of cell membranes, leading to the death of bacteria and fungi . This ingredient has anti-inflammatory, antifungal and antibacterial effectiveness, mostly directed against Streptococcus spp., Proteus spp., Staphylococcus spp., Pseudomonas aeruginosa and Escherichia coli. Its sebostatic effect (normalizing the functionality of the sebaceous glands) and keratoregulating effects (suppressing pathological cellular growth of the superficial skin layer and eliminating excessive peeling) are also manifested.

In turn, dipotassium glycyrrhizinate (comparable to cortisol in its anti-inflammatory effect), natural oils (promoting absorption, well absorbed by the skin, nourishing and improving its protective function) and fatty ( linolenic and linoleic ) acids (which are protective components of the skin barrier and support its functionality) potentiate the overall effect of the cream.

Indications for use

Shower gel

For hygienic care of the skin of the face and the rest of the body (if necessary) for the following pathological skin conditions: psoriasis ; inguinal dermatophytosis; seborrheic dermatitis ; pityriasis versicolor ; dermatophytosis of smooth skin; atopic dermatitis ( neurodermatitis , eczema ); microsporia (in order to prevent reinfection of fungal strains on other skin areas of the body when washing).

Cream gel and spray

For hygienic skin care for mild, uncomplicated forms of acne , occurring with or without inflammation, as well as for moderate, uncomplicated forms of acne , occurring with or without inflammation (during complex treatment)

In order to prevent the formation (initial or repeated) of fresh comedones and acne .

Shampoo

For hygienic care of the scalp (hair and skin) for skin diseases such as: atopic dermatitis , which appears on the scalp; dandruff ; psoriasis of the scalp; seborrheic dermatitis occurring on the scalp; oily/dry seborrhea ; itching of the skin of the scalp.

Anti-allergenic cream

For hygienic skin care for any pathological skin condition that occurs with symptoms of itching , irritation, peeling and redness in patients over 12 months ( psoriasis , neurodermatitis , atopic/seborrheic dermatitis, eczema , etc.).

In order to eliminate various skin allergic manifestations .

To alleviate the condition of the skin after superficial burns (thermal, solar).

For uncomfortable sensations after an insect bite .

In all pathological cases when external glucocorticoids are contraindicated (including facial skin) or when the patient is wary of their use.

How to use zinc ointment

Zinc ointment is used in pediatrics as a protective agent against diaper rash. In addition, it is recommended to lubricate the baby's delicate skin under the diaper every time after bathing. Zinc creates a reliable barrier that protects children's skin from constant contact with urine and loose stool. By applying zinc ointment to the buttocks daily, you can protect your baby from diaper dermatitis.

The disinfecting effect of the drug is used when treating wounds. By applying the composition to abrasions, you can avoid infection, prevent acidification of the damaged surface, and speed up the process of skin regeneration.

The main indications are:

  • diaper rash;
  • scratches;
  • dermatitis;
  • eczema;
  • cuts.

In addition, zinc ointment is used to care for the elderly and immobile patients. Treatment of bedsores slows down their spread and disinfects, which eliminates the risk of secondary infections.

Instructions for use Cynovit

Cynovit gel, instructions for use

Before use, the bottle of shower gel should be shaken vigorously several times. Then, opening the lid, squeeze out the required amount of gel from the bottle and distribute evenly over the skin in need of treatment, leaving it there for 2-3 minutes. After this time, it is necessary to thoroughly rinse off the remaining gel with warm water.

Cynovit gel, throughout the entire period of treatment of fungal pathologies of the skin or other skin diseases ( eczema , atopic/seborrheic dermatitis , etc.), should be used as the only cosmetic/medicinal product for washing the skin of the face and body (do not use other medicinal ointments , creams, lotions, etc.).

After completion of treatment, you can use shower gel for prophylactic purposes, applying it to the skin 1-2 times every 7 days.

Instructions for cream gel

Cynovit cream-gel is indicated for external use once or twice every 24 hours (morning and evening), applying the product to the affected skin areas of the body and/or face in an even thin layer.

For preventive purposes (to prevent the occurrence of fresh pimples and/or blackheads ), the cream-gel should be applied once a day before bedtime.

After the disappearance of the negative symptoms of the skin disease, it is necessary to continue the usual procedures for applying the cosmetic product for another 7-14 days.

The duration of use of the cream gel is not limited.

Cynovit shampoo, instructions for use

The use of shampoo involves uniform distribution of its small volume over the entire surface of the scalp. Then, for 60 seconds, gently massage the skin under the hair with soft movements of the hands. Then you need to thoroughly rinse off the shampoo, reapply it to the same area, leave it there for 2-3 minutes and rinse your hair thoroughly.

In order to eliminate dandruff , a 30-day use of shampoo is recommended at intervals of 2-3 times every 7 days.

To prevent dandruff , you should use shampoo once or twice a week.

Instructions for the spray

Before using the spray, you need to vigorously shake the bottle several times, then from a distance of approximately 15 centimeters, evenly spray its contents onto problematic skin surfaces.

To apply the spray to the skin of the face, it is necessary to spray the contents of the bottle onto a cotton pad or swab from a distance of approximately 5 cm, and then wipe the affected skin areas on the face with it.

Problematic skin areas should be treated twice every 24 hours (morning and evening). After the disappearance of external manifestations of the skin disease, it is necessary to use the spray for another 7-14 days.

For preventive purposes (to prevent the occurrence of fresh pimples and/or blackheads ), the spray should be sprayed once or twice a day.

The duration of use of the spray is not limited.

Cynovit cream, instructions for use

Anti-allergenic cream should be used twice every 24 hours (morning and night), applying it in an even thin layer to the affected skin areas of the face and/or other parts of the body.

The duration of therapy for dermatitis is 3-4 weeks, treatment for psoriasis takes 4-6 weeks. For other skin pathologies, it is practiced to apply the cream until the external negative manifestations completely disappear.

Contraindications

The ointment is not used to treat skin diseases in patients prone to allergic reactions to the components of the drug.

Zinc ointment is not applied to the mucous membranes of the mouth. Once zinc enters the bloodstream through the esophagus, it can cause poisoning, which can lead to convulsions, allergic skin reactions, nausea, vomiting and dizziness. Exceptions may be the mucous membranes of the anal ring and foreskin, where the ointment can be applied to relieve the inflammatory process, accelerate the healing of cracks and disinfect the surface.

Analogs

Analogues of cream, gel, shampoo, cream-gel and spray Cynovit are represented by external medicinal agents used for similar indications:

  • Zinc ointment / paste ;
  • Belosalik;
  • Desitin;
  • Cutivate;
  • Sudocrem;
  • Bepanten;
  • Advantan;
  • Tsindol;
  • Akriderm;
  • Forethal;
  • Primalan;
  • We see;
  • Tsinocap;
  • Protopik;
  • Ugrin , etc.

How does zinc ointment work on acne?

Use in cosmetology has shown its effectiveness against acne. Skin rashes caused by excessive secretion from the sebaceous glands may disappear if zinc ointment is used correctly:

  1. Cleanse skin of makeup and impurities.
  2. Wipe skin dry.
  3. Apply zinc ointment to the area affected by acne.
  4. Leave overnight.

Zinc will dry out areas of the skin and prevent the sebaceous glands from producing sebum.

Reviews about Cynovit

Reviews of Cynovit shampoo when used against manifestations of psoriasis , dandruff and other similar diseases are divided approximately equally. Some people were completely satisfied with its effect, others, on the contrary, did not feel any positive effect of the shampoo and even identified a number of side effects ( dryness , tangling and even hair loss ).

Against this background, reviews of the shower gel are much better, perhaps due to the smaller appearance of various skin rashes on areas of the body that are devoid of dense hair.

Reviews for cream-gel and spray for acne and acne are approximately the same and in most cases are positive. Spray and cream-gel for problem skin have proven themselves quite well and are quite popular among people with various diseases accompanied by skin rashes all over the body. Negative reviews about Cynovit spray and acne cream gel mainly indicate gradual addiction to the ingredients of these products, after which a decrease in their effectiveness is observed.

As is the case with shampoo. reviews of Cynovit cream were distributed approximately 50/50 between positive, when the effects of the cream helped get rid of skin rashes , and negative, when its use did not lead to any changes in the condition of the skin.

Non-hormonal ointments for psoriasis

Non-hormonal agents are considered moderately effective and at the same time inexpensive ointments for psoriasis. Their advantages compared to hormonal ones include:

  • relative safety;
  • lack of addiction;
  • lower cost;
  • possibility of long-term use without harm to health;
  • no serious side effects;
  • preservation of hormonal levels;
  • no load on the liver and kidneys;

But even with all the advantages, non-hormonal ointments for psoriasis cannot be called truly effective. Unlike hormonal ones, they have a much weaker effect. Their effect does not appear so quickly, so they are prescribed only for mild manifestations of psoriasis. They are also considered safer for the treatment of psoriasis in children.

Non-hormonal ointments eliminate peeling, swelling, itching, relieve inflammation and irritation. In addition, despite the safer composition, the use of such drugs does not exclude the development of an allergic reaction if a person is intolerant to one or another component.

Depending on the effect they provide, all non-hormonal ointments are divided into several categories:

  • Others: ichthyol, cartolin, grease, tar, naphthalan. They have anti-inflammatory and antiseptic effects. But it must be borne in mind that such ointments are not recommended for the progressive stage of psoriasis and for large lesions. Tar ointment is contraindicated in phototherapy because it has a photosensitizing effect.
  • Herbal medicines. This includes products based on sage, celandine, aloe, elecampane and other plant components. They are considered the safest of all non-hormonal ointments. But the plant base can cause allergic reactions.
  • Keratolytics: zinc, salicylic, zinc-salicylic. Their main property is the exfoliation of dead cells, which in psoriasis do not have time to be rejected. Keratolytics can cause increased inflammatory reactions, a burning sensation, and increased pigmentation of surrounding healthy skin.

Moisturizing ointments are used as non-hormonal auxiliary agents for psoriasis. But they only help eliminate the feeling of dryness and tightness of the skin.

Features of non-hormonal ointments

Salicylic ointment for psoriasis is one of the most inexpensive, but it must be borne in mind that its action for such a serious disease is often insufficient. They show good exfoliating, softening and antiseptic effects, but like other non-hormonal ointments, they take at least 2 weeks to appear, and sometimes later.

The same can be said about the use of grease-based ointment for psoriasis. In addition, these are very specific products that have a pungent odor. It can stick to furniture and clothing and is very difficult to wash off.

Among the listed ointments there are no those for the use of which clinical trials have been conducted. This means that their effectiveness is only confirmed by the experience of some users. Clinical trials were carried out only on the following drugs:

  • as Pimecrolimus (Elidel cream);
  • Calcipotriol (Davonex);
  • Zinc pyrithione (Zinocap).

This suggests that their use can indeed be beneficial. But Pimecrolimus, if used uncontrolled, has a risk of infection, and Calcipotriol should not be used if more than 30% of the skin surface is affected, as this can lead to hypercalcemia.

The only extremely safe remedy remains zinc pyrithione. Thus, answering the question of which ointment is best for psoriasis, we can say that Zinocap. But this does not negate the fact that its effect is still weaker than that of hormonal drugs.

Cynovit price, where to buy

In Russia, the average price of Cynovit shampoo is 240 rubles, the price of Cynovit shower gel (washing gel) is 250 rubles, the price of cream gel and the price of Cynovit spray is 300 rubles, the price of Cynovit cream is 330 rubles.

In Ukraine, the average price of Cynovit shower gel and cream gel is 140 hryvnia, you can buy shampoo and cream for 150 hryvnia, the cost of a spray is approximately 160 hryvnia.

  • Online pharmacies in RussiaRussia
  • Online pharmacies in UkraineUkraine

ZdravCity

  • Cynovit anti-dandruff shampoo 150 mlGreen Dubrava JSC
    RUB 292 order
  • Cynovit spray for problem skin 75 mlGreen Dubrava JSC

    RUB 325 order

  • Cynovit cream for irritation, redness, peeling and itching 40mlGreen Dubrava JSC

    RUB 292 order

  • Cynovit shower gel 150mlGreen Dubrava JSC

    RUB 258 order

  • Cynovit cream-gel for the care of problem skin 35mlGreen Dubrava JSC

    350 rub. order

Pharmacy Dialogue

  • Cynovit (shampoo 150 ml)Green oak grove

    RUB 297 order

  • Cynovit (cream-gel for acne, pimples/blackheads, tube 35ml)Green oak grove

    405 rub. order

  • Cynovit (cream for skin test 40ml)Green oak grove

    RUB 332 order

  • Cynovit (gel for shower 150ml)Green oak grove

    300 rub. order

  • Cynovit (spray for skin problems 75ml)Green oak grove

    RUB 374 order

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