How to cure hepatitis C with modern drugs and not go broke

One day I turned as yellow as a lemon.

It was a cold January 2000. I woke up with chills, looked in the mirror and was stunned: the whites of my eyes turned into “yolks”, and my skin acquired a cheerful shade of citrus fruit. A terrible hydrogen sulfide belch also appeared, and I realized that I urgently needed to see a doctor.

Go to the doctor

Our articles are written with love for evidence-based medicine. We cite reputable sources and seek comments from reputable doctors. But remember: responsibility for your health lies with you and your doctor. We do not write prescriptions, we give recommendations. Whether you rely on our point of view or not is up to you.

How I was diagnosed

The local therapist immediately called an ambulance, which took me to the city infectious diseases hospital, to the ward with the same “fruits”. Then a blood test and diagnosis: viral hepatitis C.

I won’t say that the news about hepatitis shocked me. It just so happened: reckless youth in the dashing nineties. I couldn’t let the heroin wave pass me by - I got completely screwed. At that time, I had already had more than two years of “experience.” And although there was still money for a new syringe, the use of common utensils to prepare the potion for use occurred sporadically. Back then I couldn’t believe it was so dangerous. I still have no idea at what point I caught the virus. But if it’s through drugs, there’s no option.

What is viral hepatitis C

Hepatitis C is a liver disease caused by the hepatitis C virus. The disease can occur in both acute and chronic forms.

Hepatitis C is one of the main causes of liver cancer. Chronic inflammation provokes damage to this organ, which often leads to malignant degeneration of cells.

The hepatitis C virus is transmitted through blood. Transmission is possible through injecting drug use, during medical procedures, including transfusion of contaminated blood, and in rare cases through sexual contact.

In 2022, hepatitis C was detected in 45 thousand Russians. In total, this disease in our country affects, according to various estimates, from 2.2 to 4.9 million people. 70% of them learned about their diagnosis by accident.

The attending physician’s lecture about the “gentle killer,” cirrhosis and other delights of this incurable, according to the lecturer, disease did not impress me at all. At the age of 25, it wasn’t that I didn’t believe, but rather, I didn’t see anything terrible in the fact that I would die someday later. And this “later” will not happen tomorrow or even the day after tomorrow. And if it’s “incurable,” then what’s the point of reflecting?

With these thoughts, I was discharged two weeks later, having removed all the symptoms of acute hepatitis with the help of droppers, injections and tablets. With the discharge, I went to the infectious disease specialist at my place of residence, and she registered me. She ordered me to get tested every six months. On this we parted ways.

For the next ten years I hardly remembered my problem. My head fell into place: I settled down, changed my lifestyle, got married. My wife found out about my virus in the first days of our acquaintance. Being an educated and sensible person, she took this news adequately. In the future, we did not focus on this point. The impact of the disease on our life together was manifested only in the need to use condoms, since the risk of transmitting the virus to a woman during unprotected sexual intercourse is quite high, 5–7%. As for the rest, hepatitis did not remind me of itself.

At some point, I noticed that I still knew exactly where my liver was located. Any increased physical activity led to a feeling of bloating and heaviness in the right hypochondrium. Since bad habits in the form of alcohol were still present in my life, I began to notice that hangovers were becoming more severe and were accompanied by a bitter taste in my mouth. After some time, similar symptoms began to be caused by banal overeating. I again realized that I urgently needed to see a doctor.

"Karsil": instructions for use

The dosage depends on the patient’s age and disease:

• adolescents from 12 years of age and adults, 1-2 tablets 3 times a day;
• children from 5 to 11 years old inclusive - 2-3 times a day in an amount calculated from the ratio of 3 mg of active substance per kilogram of body weight;
• in case of exacerbation of the disease, adults are advised to take double the norm (compared to the standard) 3 times a day.

The general course of therapy depends on the patient’s age, his general condition and the nature of the disease. Typically the duration is 3 months. After this you need to take a break. Subsequent repetition of treatment is discussed with the doctor.

How I thought about treatment

The infectious disease specialist from the local clinic, a woman about 60 years old, was neither happy nor upset when she saw me. The duty officer asked why I had never come in all this time, and wrote me a referral for tests with a week to come for the results.

A week later I was like a bayonet. I found out that everything is bad with me, as it should be given my attitude to health: the viral load - the number of viral particles in the body - is growing, liver enzymes are also elevated, and on ultrasound the liver itself is not well enlarged.

I repented of my sloppiness and promised to improve. The doctor prescribed me medications to maintain liver health - so-called hepatoprotectors, gave me a printout with a special diet and was already ready to say goodbye to me. And then I asked if there was any news in terms of a complete cure for my hepatitis. Her answer surprised me a little:

- There is treatment, but do you need it?

It turns out that since the nineties there has been a treatment regimen for hepatitis C with interferons - special proteins similar to those secreted by the human body in response to the invasion of any viruses. It is believed that this protein is capable of modifying the membrane of uninfected liver cells and thereby protecting them from the penetration of the virus. In general, the scheme works, but there are some nuances:

• The effectiveness, depending on the genotype of the virus, ranges from 45 to 90%.
• The course of treatment lasts from six months to one and a half years.
• Treatment is by daily injections.
• The drugs have a huge list of side effects, some quite serious.

Simply put, it is possible to undergo treatment, but it is long and difficult, with no guarantee of cure and with a high probability of significantly worsening the quality of life as a result. But there is a program, and they will put me on the waiting list if I insist. In the meantime, as a farewell, the doctor gave me a business card with contacts of a local group of patients undergoing interferon treatment.

And here I dived deeply into the topic for the first time. I met and communicated with a girl named Yulia, who at that time had been on the pegylated interferon + ribavirin regimen for almost six months. Pegylated interferon works in the body much longer than usual. Thanks to this, Yulia needed to get an injection once a week, and not daily. But this is every week throughout the year! And you can’t get injections in your hands or give them to yourself. You need to come to the clinic every week. And that's not the worst part.

The most unpleasant thing is the side effects. From the first injections, the temperature rises and a prolonged flu-like state sets in with aching bones. Yulia told me that you get used to it after about a month. Much worse is constant itching of the skin and various digestive disorders. Almost all patients also experience severe depression, which in itself is a serious pathological condition.

And the most painful topic for the female half is hair. During treatment they begin to fall out. I’ll say right away that Yulia endured all these “charms” like a steadfast tin soldier. Working, raising a child. She also constantly encouraged me to start therapy. And thank God, her treatment worked, the virus went away and did not return.

But then I didn’t make up my mind. I read how they give up injections halfway through, when there is no more strength to continue. Or due to lack of response to treatment. I thought about it and didn’t sign up for the program. In addition, with hepatoprotectors, my discomfort gradually subsided, and for several more years I limited myself to symptomatic treatment.

How I learned about modern methods of treating hepatitis C

I would like to note that I went through all the tests and studies, as promised to the doctor, strictly. But everything that they did at the clinic - they took blood for biochemistry and performed an ultrasound - did not help in any way to assess how quickly my hepatitis was moving towards cirrhosis. Another safe and painless diagnostic method was fibroscan - ultrasound using a special device that determines the degree of fibrosis, that is, damage to liver tissue. If there is no access to a fibroscan, the only option left is a biopsy - a puncture in the liver with a special needle, which removes a piece of tissue for examination.

Fibroscan was found in a specialized gastroenterology center, and I went there. I paid about 2500 R and went through the research. I was diagnosed with the first, very initial stage of fibrosis. By luck, the result had to be taken from a local hepatologist. The young woman explained to me the essence of the research results and asked why I was not receiving treatment.

I immediately figured that they probably had their own paid program at the center. Well, I immediately briefly said everything I thought about interferon therapy. She wasn't embarrassed at all. I just asked why I don’t take normal pills.

- Normal pills?

Then I learned that three years ago the American company Gilead registered the first tablet form of a drug that directly affects the RNA of the hepatitis C virus and prevents it from being copied. This drug is called sofosbuvir. Combinations of this drug with later new products from the DAA line - direct-acting antiviral drugs - are by far the most effective means of treating hepatitis C. The cure rate is 95-97%, with virtually no side effects, and in tablet form!

This was great news. The bad thing is that a course of treatment with the original drug cost somewhere at the price level of a five-room apartment with European-quality renovation. But we were lucky. Gilead has licensed 11 Indian companies to produce generic drugs for the needs of poorer countries. Therefore, it was possible to purchase an analogue of the original drugs for quite reasonable money. The problem was that generics were not officially supplied to Russia, since our country was not considered the poorest. It was necessary to contact authorized trading companies in India directly and place the order privately.

How effective is modern therapy for hepatitis C?

Nikolay Golovenko gastroenterologist at GMS Clinic

With the advent of drugs from the group of RNA polymerase inhibitors, treatment of hepatitis C with interferons has lost its relevance. For example, the effectiveness of treatment with PEG - pegylated interferon - did not exceed 60%. Treatment took from six months to two years and was accompanied by multiple side effects.

Moreover, the effectiveness of RNA polymerase inhibitors, according to various sources, ranges from 80 to 95%. In case of insufficient effectiveness in the first three months, this drug is prescribed for another 12 weeks, which, as a rule, leads to complete elimination of the virus and recovery of the patient. The exceptions are patients with transformation of hepatitis into cirrhosis and patients with hepatocellular carcinoma.

Unfortunately, according to the requirements of the Ministry of Health, infectious diseases hospitals and hepatology departments can only purchase the original drug, the cost of a course of treatment ranges from 500,000 to 1,000,000 RUR. Therefore, due to a shortage of drugs, some patients are still prescribed interferon therapy. Or they informally offer treatment at their own expense.

Thanks to the appearance of generics on the market, the cost of a course of treatment with polymerase inhibitors has decreased and currently ranges from 35,000 to 100,000 RUR. The effectiveness of generics is approximately the same compared to the effectiveness of the original drug.

The hepatologist estimated the average cost of a course of generics at $1,000 (74,166 RUR). For the exact amount, it was necessary to decide on a specific drug and its quantity, and then check with the sellers. The sellers in this case were intermediary companies that had established communication with the Indian side. These were pure intermediaries. They simply processed requests from Russian patients on their websites and forwarded the information to a trading partner in India. Buyers paid for the medicines and delivery directly to the Indians.

Many individuals offered drug delivery services. The doctor gave me a business card from one of these “helpers,” who, according to her, had already been checked. But first I had to make a fundamental decision to take such a sharp turn. The new information looked too fabulous to be true.

What is Karsil?

Karsil is a drug from the group of hepatoprotectors. The active component of the drug is silymarin - a substance contained in milk thistle.

Silymarin has an anti-inflammatory effect that helps reduce liver damage associated with viral infections by mitigating the inflammatory cascade and modulating the immune system.

Carsil has an antioxidant effect, which is detected by inhibiting the penetration of toxins into the liver. Hazardous substances are neutralized physiologically, since the active substance interacts with free radicals, interrupts the process of lipid peroxidation and prevents cell damage.

The drug produces the synthesis of proteins and phospholipids in areas of the liver that have lesions. This way it normalizes lipid metabolism, stabilizes and promotes cell membrane regeneration.

How I decided to take generic treatment

And I took a break. I was observed for about another year at the gastrocenter. During this time, my maintenance treatment changed somewhat: the doctor replaced an expensive hepatoprotector drug with a cheaper drug and additionally prescribed several courses of anticholecystitis therapy to maintain gallbladder function. It turns out that in most cases any pain in the liver area is caused by the gall bladder. I only bought pills - doctor’s consultations and all examinations were free under the compulsory medical insurance policy.

At the same time, at this time I was actively surfing the Internet in search of information about a new treatment. I found out that these revolutionary tablets act as RNA polymerase inhibitors. They inhibit the enzyme necessary for the virus to multiply. I studied a lot of specialized forums with reviews about providers' websites, treatments and results. Everything looked like the treatment was really working.

I understood that something needed to be done about the pain. The viral load continued to grow, the symptoms also caused more and more inconvenience, and it was clear how it would all end.

And in September 2022, I finally made up my mind, saved up money for treatment and went to the doctor again, took a genotype and viral load test. Based on the test results, the hepatologist selected the drug Ledihep for me, an Indian generic of the original drug Harvoni. The active ingredients are two polymerase inhibitors: sofosbuvir and ledipasvir. The course of treatment was 12 weeks, one tablet per day. It was necessary to buy 3 jars of the drug, 28 tablets each.

I read specialized forums and, based on reviews, chose the site where I planned to place an order, but just in case, I also contacted the person on the doctor’s business card. My costs if ordering through him would be $300 higher compared to ordering through the website. I figured I could handle it myself and refused the services of a private contractor.

This is what the main page of the site where I bought medicine looks like. Source: HCV24

Composition and description of tablets "Karsil"

"Karsil" refers to antitoxic drugs that clear the liver of toxins (hepatoprotective effect). It is produced only in the form of tablets - there are 80 pieces in one package. The active ingredient is silymarin: it is an extract of the fruit of the spotted milk thistle plant. Each tablet contains 22.5 mg of this component.

The drug is available without a prescription, but it is recommended to consult a doctor before starting therapy. The tablets are stored under normal conditions (room temperature not higher than 25 degrees, moderate humidity). The shelf life is 2 years from the date of production.

How I bought Indian tablets

Now I catch myself thinking that I was lucky several times in this story. I was lucky to meet a competent hepatologist and lucky with the choice of the supplier’s website. After contacting me through the feedback form, my personal manager contacted me. She accompanied me promptly and competently until the very end of the transaction. In general, the organization of sales on our Russian side was a pleasant surprise.

First of all, in response to my application, I was introduced to the entire available range of medications with the active ingredient I needed. Since I had already initially decided with the doctor about the drug, I did not change anything and confirmed my order for three jars of Ladyhep. In response, they sent me payment details and an invoice - that’s what an invoice for payment is called in international commerce.

The intermediary offered five different generics of Harvoni, which varied slightly in price

This is what the payment details sent to me looked like:

Invoice for my order, the total cost of which was $740

With the invoice, I went to my bank and made a currency transfer. Then I sent a scan of the payment notification to the manager

My new generation drug. Source: LadyHep

I had to wait 12 days for confirmation of funds being credited. But the next day after confirmation, the parcel was sent immediately. I received a tracking code and waited another 12 days. In total, 27 days passed from the moment of application on the website to the moment of receipt of the shipment at the EMC point of issue.

I exhaled, decided to wait six days until the beginning of November, so that it would be easier to count the weeks, and start taking pills from the first.

How to legally import unregistered medicine into Russia

Polina Naydenkova lawyer in the field of pharmacology and medicine

There are two legal ways to buy the drug abroad: simple and complex.

Downtime is when the patient himself brings it in his luggage for his treatment. This option cannot be implemented by power of attorney; only legal representatives - parents and guardians - can transport medications. Obviously, not every patient and does not always have such an opportunity - this is a disadvantage of this method. In addition, this method is only suitable for drugs registered in the Russian Federation - you can check the availability of registration through the State Register of Medicines. However, if the drug is a prescription drug, you will need a prescription from your doctor to transport it.

The difficult way is to import it under a special permit issued by the Russian Ministry of Health. Under this permit, medications can be transported not only in person, but also by post.

To obtain such permission, you need to submit a package of documents to the Russian Ministry of Health:

• Protocol of the consultation of a federal specialized medical organization or institution of the Russian Academy of Medical Sciences or an institution of a constituent entity of the Russian Federation in which medical care is provided to a specific patient. This protocol must indicate the need to prescribe the drug for health reasons, and such a need for which the prescription of a drug registered in the Russian Federation is impossible. The protocol is signed by the chief physician of the institution.
• An appeal from the regional health authority about the need to import an unregistered drug, accompanied by a copy of the council’s conclusion.
• An electronic copy of the passport or birth certificate of the patient who is prescribed the drug, certified not by a notary, but certainly by the medical institution providing medical care.
• Application for obtaining permission to import into the territory of the Russian Federation an unregistered medicinal product necessary to provide medical care for the vital indications of a particular patient. The application form was approved by the Russian Ministry of Health.

All this - both on paper and at the same time in the form of an electronic document - is submitted to the address [email protected] and to the Russian Ministry of Health. The Russian Ministry of Health will review the documents and make a decision within one week. Such an application is not subject to state duty.

Violation of the rules for the import of drugs unregistered in the Russian Federation is subject to administrative and criminal liability. If a medicine is not registered in Russia, and there are no documents confirming the right of a specific individual to receive it, government agencies recognize it as falsified or of poor quality.

According to Art. 6.33 of the Code of Administrative Offenses of the Russian Federation, illegal import of unregistered medicines into the territory of the Russian Federation entails the imposition of an administrative fine on a citizen in the amount of 70,000 to 100,000 RUR.

If the state sees in the actions of an individual a sales goal - this depends on the size of the batch of imported drugs - liability is threatened in the form of imprisonment for a term of 3 to 5 years.

How to take Karsil?

When treating liver diseases, you should stick to a diet and not drink alcohol. Use during pregnancy and lactation.

At the moment, there are no reliable studies on the effect of the drug on intrauterine development of the fetus or lactation. The need for treatment with this drug can only be determined by a doctor after a complete examination. The use of the drug Karsil can only be determined by the fact that the benefit from such therapy for the mother will be higher than the potential risk for the child.

Note!

If you have problems with the functioning of the vestibular apparatus, then take the drug with caution.

How I received treatment

And so it began. One tablet per day, preferably at the same time, with plenty of water. According to the instructions, side effects could appear in the first week of treatment: headache, rash and itching, fatigue and a few other non-serious symptoms. But according to my doctor, none of her patients have encountered them.

And I didn’t feel anything at all. I swallowed the pill like a piece of chalk, following a signal on my phone, and forgot about the treatment for a day. There were so many new sensations that, closer to the two-week mark, the thought began to itch: “Have they really been bred into a dummy?”

Two weeks later I went for the first control test. There are several of them: after 2, 4, 12 weeks, and then, after the end of treatment, after six months and a year. I took a qualitative PCR test, a test that determines the presence of a virus in a blood sample. It is the fact of presence itself, and not its quantity. I would like to note right away that I took all the control tests at my own expense in commercial laboratories, since I did not officially undergo treatment and there were no grounds for prescribing tests under the compulsory medical insurance contract. Depending on the laboratory and current promotions, I paid from 500 to 700 RUR for each sample.

The doctor explained that the first test, two weeks after the start of treatment, can be either positive or negative. The analysis after four weeks should already be negative, like all subsequent ones. If not, you need to supplement the treatment regimen or interrupt it.

And now my first two weeks are over. I really hoped that I would receive confirmation that everything was not in vain. But the analysis turned out to be positive. And although I knew that the virus could still be detected at the first cutoff, after this result I began to openly worry about success. The next two weeks were the hardest. I still spent hours taking pills, dieting, giving up alcohol completely, and dreading the next test. And finally he waited.

For the first time in 17 years, the test did not detect HCV in my body. My “everything is lost” mood instantly changed to “hurray, we are breaking, the Swedes are bending.” And although I knew that sometimes the virus returns several months after treatment, it was at that moment that I believed that everything would work out for me. I already automatically took the therapy and did not feel any side effects. At the end of the course, the test again did not detect the virus in my blood.

The course ended, and I began to get used to living without hepatitis. I still couldn’t believe that the once incurable disease was gone. And I felt that I had left for good, even though there were still two control tests ahead.

By the first half of the year without hepatitis, I began to feel the effect of the treatment. The bitter taste in my mouth stopped bothering me. The feeling of bloating in the right hypochondrium disappeared, sleep improved, and performance increased. I had one last control test left to say with a clear conscience: I had cured hepatitis C.

This is how my epic with the treatment of hepatitis C ended. The legacy of the disease left antibodies in my blood, which are now always with me. Therefore, now it makes no sense for me to carry out ELISA - an antibody test to diagnose hepatitis - and doctors need to be warned about this. At the same time, despite the presence of antibodies, after treatment, immunity to the virus is not developed, so I can catch this infection in the second round. There are also problems with the gallbladder - cholecystitis has not disappeared. But you can live with it, it can be treated, and you can’t infect anyone with it.

My first positive test after two weeks from the start of treatment

The first “minus” four weeks after the start of treatment

12 weeks from the start of treatment - no virus detected

Six months after treatment: still no virus

A year after treatment - no virus, hurray!

Choleretic agents Pharmachim Sopharma KARSIL - reviews

svitulya1305
https://citykey.net/review/mne-pomog-7

Good afternoon I want to share my experience of using this medicine.

I met Karsil as a teenager (I was about 13 years old). And often my liver ached, there was a tingling sensation in my side, and I felt nauseous. It seemed that everything was normal with the gall bladder, and there were no bends, but still, from time to time, unpleasant sensations bothered me. Especially when there was physical activity (for example, a 3 km cross-country race at school, after which my liver hurt so much). My mother always gave me Karsil and it helped me a lot, the unpleasant symptoms subsided and I felt good.

But my mother had problems with her bile ducts, so these pills were and always remain in her medicine cabinet. They help her well. She periodically takes Milk Thistle as an herb to cleanse her liver.

The drug is very good, natural, and always helps us overcome unpleasant symptoms.

Affordable. Karsil is always indispensable in my mother’s first aid kit, since after suffering from hepatitis her liver suffers greatly.

In general, it’s a good drug, I can’t say anything bad.

Brandy

https://citykey.net/review/zamechatelnyy-preparat-dlya-podderzhaniya-pecheni

Probably, many people have periods when the liver is forced to work more actively than usual. We are talking about long feasts during the New Year holidays, summer vacations and other periods when complete culinary and alcoholic relaxation of soul and body sets in, as well as taking antibiotics. It is during such periods that the liver needs support, and Karsil is perfect for these purposes. It is absolutely harmless to the body, since it is a completely natural drug, and therefore it can be taken for quite long periods.

My husband and I have known about this drug for quite some time, and periodically take it to support the liver. Now, even after the stormy holidays, we do not feel any discomfort in the right hypochondrium. I also took it during both of my pregnancies, because the fetus put a lot of pressure on my liver, and it periodically hurt. By the way, the price is quite reasonable, much cheaper than other advertised drugs. I recommend this drug to everyone I know, I have never been dissatisfied.

Anton

https://med-otzyv.ru/lekarstva/153-k/24997-karsil#scomments

A good, affordable hepatoprotector. It helps only with long-term use, at least two months. Has a natural composition. Safe. I have already taken Karsil several times to protect the liver. I didn’t notice any side effects. He tolerated the treatment well. During treatment, you must follow a diet and completely abstain from alcohol.

Roma

https://med-otzyv.ru/lekarstva/153-k/24997-karsil#scomments

Karsil is an excellent medicine for liver prevention. I am prescribed a lot of pills and have to take handfuls of them. The doctor also advised me to take a course of this medicine so that the liver would not be so susceptible to such attacks from the pills. I underwent examinations and tests showed a completely normal condition of the liver under such a load of all sorts of medications. The main thing is that there are no side effects, the capsules are quite suitable for my body. The main thing is to complete the course completely; I take them for one month, twice a year.

hunter852013

https://otzovik.com/review_5376551.html

Advantages:

Helps

Flaws:

No

I have always associated these pills with something inexplicably unpleasant, associated with serious illnesses. I haven’t encountered them yet, but some relatives have. I had to observe live what and how. At first I didn’t believe in these pills because, to be honest, I thought they were weakly effective. The thing is that recently something bad happened - some foods had an effect on the liver, maybe fatty or low quality, or something else... It remained a mystery to me. One of the relatives needed to take the pills, and the sooner the better. At first they wanted to buy an expensive product because it seemed to work faster. But for some reason they refused, even though there was enough money. I was assigned to observe the course of treatment for 3 months. All I had to do was remind and mark taking the pills. 6 tablets each As of today, 4 months have already passed, of course the result was and is still preserved. And this evening I learned that expensive medicines are not always medicines - there is a chance of running into an empty capsule from the package. This is how it also happens - when there is an opportunity to buy, but on the contrary, there is no desire. I recommend purchasing these tablets to those who need results and who want to restore their health. The price is for 1 pack = 80 tablets. For this course of treatment, 6 tablets per day were needed. If there was a miss, then this was followed by doubling the dosage to equalize the number of tablets taken. I needed 540 tablets, which is almost 7 packs. One pack will last on average almost 2 weeks.

oleg898

https://otzovik.com/review_898295.html

Advantages:

price-quality ratio"

Flaws:

They are not here

Considering that I have duodenal ulcer, I have to take special care of my liver. And quite often, when I had to undergo treatment in a hospital, Karsil was prescribed to me, as well as after discharge. A very inexpensive drug, unlike analogues, has an excellent medical effect, smoothes the effect of medications taken that negatively affect the liver. Judging by my impressions from studying the composition, the drug is natural, does not particularly contain chemical additives, so, in my opinion, it is one of the best in its category, especially if you take into account the price-quality ratio. I confidently recommend it to anyone who has liver problems and for prevention purposes. In fact, you can find the drug in most pharmacies, which is also an advantage.

alinahardina

https://otzovik.com/review_3091066.html

Advantages:

Natural composition, effective

Flaws:

didn't find it

Good day. There was a time when I was very sick and had to take antibiotics, thereby harming my liver. Then, after another trip to the doctor, he prescribed me to take the drug Karsil. First of all, before taking an unfamiliar drug, I read reviews about it, which were mostly positive. Then I decided to accept it without any doubt. There are only 80 tablets in a pack. They are small, brown in color, and have a sweet taste. I took them immediately after antibiotics three times a day. After the course of antibiotics ended, I continued to take Karsil for some time on the doctor’s recommendation. Now my liver is fine, despite taking antibiotics. The composition of the tablets is absolutely natural. The price is ridiculous. Thank you for your attention to my review! I wish you not to get sick!

sbuzmakova

https://irecommend.ru/content/pomogaet-pecheni-posle-pogreshnostei-v-pitanii-posle-priema-alkogolya-i-antibiotikov-tak-zhe

I have already written about the benefits of milk thistle meal for our liver here

https://irecommend.ru/content/pomogaet-sbrasyvat-i-…. I took it regularly and am very pleased with the results. I began to recommend it to my loved ones, but as it turned out, not everyone could take it, my mother, mother-in-law and husband said in one voice that they were unable to swallow a spoonful of sawdust with water... And then my husband began to complain of heaviness in the left hypochondrium. You can’t drag him to the hospital, but something needs to be done... I started looking through the information and came across this drug:

Karsil is a hepatoprotector. Contains dry extract of milk thistle fruit (equivalent to silymarin (the active ingredient of the drug Karsil)), which is a mixture of 4 isomers of flavonolignans: silibinin, isosilibinin, silydianin and silicristin. The mechanism of action of the drug is not clear enough. It is known that the hepatoprotective effect is associated with the competitive interaction of silymarin with toxins for the corresponding receptors on the hepatocyte membrane; This is due to the membrane-stabilizing effect.

Since I know and respect milk powder, I bought a pack at the nearest pharmacy and my husband began taking it, 2 tablets 3 times a day..

Instructions for use and dosage regimen:

For adults and children over 12 years of age, for the treatment of severe liver damage, the drug is prescribed in a daily dose of 420 mg - 4 tablets 3 times a day. For the treatment of milder cases and as maintenance therapy, 1-2 tablets are prescribed 3 times a day. For prevention, 2-3 tablets per day are prescribed.

It may be hard to believe, but my husband felt the first results…………20 minutes after taking the first two pills; according to him, the heaviness in the right hypochondrium completely subsided. The holidays were just around the corner, when taking this drug there are no contraindications to alcohol, after a good feast and a little (or maybe a lot) alcohol abuse, the next morning did not seem like a terrible nightmare. I am a person who observed this from the outside and can note that the difference before and after taking the drug is very obvious. My husband did not sleep until lunch as usual and did not ask for water with a weak groan))) He woke up and asked for food!!!

For me, this drug is, of course, more convenient and pleasant to take than milk thistle meal, but the difference in price is due to the latter. But Karsil seemed more effective to me or something... Perhaps these are my personal feelings, it seems to me that this drug speeds up metabolism. I have regular bowel movements, I feel great, my stomach is light, I can’t say anything about my skin since I don’t have any special problems with it (pah-pah).

My mother also wanted to take a course, because everyone knows that the liver needs to be supported, especially in older age. She was just taking a course of antibiotics and began to complain of bitterness in her mouth, nausea and changes in taste. In my opinion, she generally often abuses all sorts of medicines, tablets, etc... But when she took Karsil, she began to experience such an unpleasant effect as bloating and increased gas. However, after taking it for a week, this side effect stopped, along with nausea and other unpleasant issues caused by antibiotics.

To summarize, I would like to note the pros and cons of this drug.

Pros:;

1. Effectively supports the liver
2. Helps after drinking alcohol, antibiotics, fatty and rich foods
3. Natural
4. Adjusts the chair

Minuses:;

1. Price (milk thistle meal with a similar effect is several times more affordable)
2. Sometimes it can cause gas and bloating.
3. Regular appointment. (some may find it difficult to take three times a day)

I wish everyone good health!

Lex-Ta

https://irecommend.ru/content/my-dumali-chto-karsil-s-fermentami-kak-allokhol-ili-mezim

My husband's pills. We once bought Karsil instead of Allochol, we were advised at the pharmacy that it seemed to be an analogue. It costs a penny, is sold without packaging, so we bought it.

My husband takes one with him on business trips, and I found a couple more blisters in the medicine cabinet today when I was sorting through medications to write reviews. I remembered how we read on the Internet about its composition and purposes and laughed for a long time when the pharmacist persuaded us to buy it.

It turned out that there were no heaviness in the stomach or problems with digestion in the direct indications for taking it. But there are: liver damage, hepatitis, cholecystitis.

And it contains no enzymes. Karsil is a herbal preparation, and only its shell, as expected, is made of all sorts of glycerols and hydroxybenzoates. And at the core is pure milk thistle extract.

The plant is known for its hepatoprotective properties and help in liver problems. I also take milk thistle meal from time to time for a comprehensive cleansing of the body. In general, apparently, a positive drug.

The husband decided to drink without fear. Even if there are no enzymes in it, milk thistle is unlikely to do any harm. And you know, Karsil helps him perfectly. With a lifestyle like my husband’s and abusing meat dishes and barbecue, it’s easier for him to live with pills.

Only it is recommended to take it for its main purposes for at least 3 months, but my husband will drink it for a week while on business trips he sits on government food and has lunch at a bistro, and then forgets for a long time. But even in such an incorrect regime, Karsil saves him. Good pills.

Allochol, of course, acts faster, but it contains plant materials, less chemicals, and the drug is inexpensive. We also recommend it to you if your doctor has prescribed it. It is well tolerated, reduces heaviness in the stomach, and regulates stool slightly, but it helps.

How much did hepatitis C treatment cost me?

Now, three years later, the situation with the treatment of hepatitis C in Russia has not changed. The state can only offer interferon therapy as free treatment programs. Generics of modern inhibitors cannot be purchased in pharmacies. The situation with the procurement of patented drugs is extremely confusing. Purchases of small quantities of expensive original drugs are periodically announced, but they are not available either in pharmacies or in programs.

This whole story with the treatment of hepatitis once again convinced me that something is wrong with the world order in general. A huge number of people do not have access to modern medicines only because large corporations decide who and how much to make money from. I also learned that we have many competent doctors, caring specialists who, in the face of this global injustice, help people literally survive. Now I'm used to searching for health-related information on the Internet. This helps, when communicating with a doctor personally, to understand who is in front of me: an expert or simply a “person with a profession” who is ossified in the dogmas of the times of obtaining a medical diploma.

Well, the main lesson, or rather a confirmation of well-known truths: you have to pay for everything and some things are better to prevent than to correct later.

I paid about 51,000 RUR for the treatment of hepatitis C

Remember

Side effects

In most cases, taking the drug is not accompanied by any complications. But sometimes side effects are possible:

• allergic reactions (itching, skin rashes);
• diarrhea;
• nausea;
• alopecia;
• dyspepsia;
• problems with the vestibular apparatus.

In rare cases, other undesirable symptoms appear, but they quickly disappear after stopping the medication.